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Predicting outcome 12 months after mild traumatic brain injury in patients admitted to a neurosurgery service

Hellstrøm, Torgeir; Kaufmann, Tobias; Andelic, Nada; Søberg, Helene L.; Sigurdardottir, Solrun; Helseth, Eirik; Andreassen, Ole Andreas; Westlye, Lars Tjelta (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)

Objective: Accurate outcome prediction models for patients with mild traumatic brain injury (MTBI) are key for prognostic assessment and clinical decision-making. Using multivariate machine learning, we tested the unique ...

White matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury

Hellstrøm, Torgeir; Westlye, Lars Tjelta; Kaufmann, Tobias; Doan, Nhat Trung; Søberg, Helene L.; Sigurdardottir, Solrun; Nordhøy, Wibeke; Helseth, Eirik; Andreassen, Ole Andreas; Andelic, Nada (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)

Identifying patients at risk of poor outcome after mild traumatic brain injury (MTBI) is essential to aid prognostics and treatment. Diffuse axonal injury (DAI) may be the primary pathologic feature of MTBI but is normally ...

The impact of immigration and visible minority status on psychosis symptom profile

Berg, Akiah Ottesen; Andreassen, Ole Andreas; Aminoff, Sofie Ragnhild; Romm, Kristin Lie; Hauff, Edvard; Melle, Ingrid (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

Purpose Immigrants have heightened risks of psychotic disorders, and it is proposed that migration influences symptom profiles. The purpose of this study was to investigate if either migration experience and/or visible ...

Childhood trauma mediates the association between ethnic minority status and more severe hallucinations in psychotic disorder

Berg, Akiah Ottesen; Aas, Monica; Larsson, Sara; Nerhus, Mari; Hauff, Edvard; Andreassen, Ole Andreas; Melle, Ingrid (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)

Background Ethnic minority status and childhood trauma are established risk factors for psychotic disorders. Both are found to be associated with increased level of positive symptoms, in particular auditory hallucinations. ...

MicroRNAs enrichment in GWAS of complex human phenotypes

Goulart, Luiz Fernando De Souza; Bettella, Franscesco; Sønderby, Ida Elken; Schork, AJ; Thompson, Kurt Wesley; Mattingsdal, Morten; Steen, Vidar Martin; Zuber, Verena; Wang, Yunpeng; Dale, Anders; Andreassen, Ole Andreas; Djurovic, Srdjan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)

Background: The genotype information carried by Genome-wide association studies (GWAS) seems to have the potential to explain more of the ‘missing heritability’ of complex human phenotypes, given improved statistical ...

The human amygdala encodes value and space during decision making

Ousdal, Olga Therese; Specht, Karsten; Server, Andres; Andreassen, Ole Andreas; Dolan, Ray J; Jensen, Jimmy Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)

Valuable stimuli are invariably localized in space. While our knowledge regarding the neural networks supporting value assignment and comparisons is considerable, we lack a basic understanding of how the human brain ...

Genome-wide analysis of attention deficit hyperactivity disorder in Norway

Zayats, Tetyana; Athanasiu, Lavinia; Sønderby, Ida Elken; Djurovic, Srdjan; Westlye, Lars Tjelta; Tamnes, Christian Krog; Fladby, Tormod; Aase, Heidi; Zeiner, Pål; Reichborn-Kjennerud, Ted; Knappskog, Per; Knudsen, Gun Peggy; Andreassen, Ole Andreas; Johansson, Stefan; Haavik, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)

Background: Attention deficit hyperactivity disorder (ADHD) is a highly heritable neuropsychiatric condition, but it has been difficult to identify genes underlying this disorder. This study aimed to explore genetics of ...

The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data

Thompson, Paul M; Stein, Jason L; Medland, Sarah E; Hibar, Derrek P; Vasquez, Alejandro Arias; Renteria, Miguel E; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J; Martin, Nicholas G; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C; Andreassen, Ole Andreas; Apostolova, Liana G; Appel, Katja; Armstrong, Nicola J; Aribisala, Benjamin; Bastin, Mark E; Bauer, Michael; Bearden, Carrie E; Bergmann, Ørjan; Binder, Elisabeth B; Blangero, John; Bockholt, Henry J; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret I; Booth, Tom; Bowman, Ian J; Bralten, Janita; Brouwer, Rachel M; Brunner, Han G; Brohawn, David G; Buckner, Randy L; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R; Calhoun, Vince D; Cannon, Dara M; Cantor, Rita M; Carless, Melanie A; Caseras, Xavier; Cavalleri, Gianpiero L; Chakravarty, M Mallar; Chang, Kiki D; Ching, Christopher RK; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E; Czisch, Michael; Deary, Ian J; de Geus, Eco JC; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D; Ehrlich, Stefan; Ekman, Carl Johan; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernandez, Guillen; Fisher, Simon E; Foroud, Tatiana; Fox, Peter T; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C; Godlewska, Beata; Goldstein, Rita Z; Gollub, Randy L; Grabe, Hans J; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel E; Gur, Ruben C; Göring, Harald HH; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey B; Hall, Jeremy; Hardy, John; Hartman, Catharina A; Hass, Johanna; Hatton, Sean N; Haukvik, Unn Kristin H.; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian B; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter J; Hollinshead, Marisa; Holmes, Avram J; Homuth, Georg; Hoogman, Martine; Hong, LElliot; Hosten, Norbert; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E; Hwang, Kristy S; Jack Jr, Clifford R; Jenkinson, Mark; Johnston, Caroline; Jönsson, Erik Gunnar; Kahn, Rene S; Kasperaviciute, Dalia; Kelly, Sinead; Kim, Sungeun; Kochunov, Peter; Koenders, Laura; Krämer, Bernd; Kwok, John BJ; Lagopoulos, Jim; Laje, Gonzalo; Landen, Mikael; Landman, Bennett A; Lauriello, John; Lawrie, Stephen M; Lee, Phil H; Le Hellard, Stephanie; Lemaitre, Herve; Leonardo, Cassandra D; Li, Chiang-shan; Liberg, Benny; Liewald, David C; Liu, Xinmin; Lopez, Lorna M; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise WJ; MacQueen, Glenda M; Malt, Ulrik Fredrik; Mandl, Rene; Manoach, Dara S; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen A; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; McIntosh, Andrew M; McMahon, Francis J; McMahon, Katie L; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant W; Morris, Derek W; Moses, Eric K; Mueller, Bryon A; Munoz Maniega, Susana; Muhleisen, Thomas W; Muller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas E; Nilsson, Lars-Göran; Nugent, Allison C; Nyberg, Lars; Olvera, Rene L; Oosterlaan, Jaap; Ophoff, Roel A; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey D; Penninx, Brenda W; Peterson, Charles P; Pfennig, Andrea; Phillips, Mary; Pike, GBruce; Poline, Jean-Baptiste; Potkin, Steven G; Putz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon L; Roffman, Joshua L; Roiz-Santianez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma J; Royle, Natalie A; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder S; Salami, Alireza; Satterthwaite, Theodore D; Savitz, Jonathan; Saykin, Andrew J; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo G; Schork, Andrew J; Schulz, SCharles; Schur, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody M; Simmons, Andrew; Sisodiya, Sanjay M; Smith, Colin; Smoller, Jordan W; Soares, Jair C; Sponheim, Scott R; Sprooten, Emma; Starr, John M; Steen, Vidar Martin; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Sämann, Philipp G; Teumer, Alexander; Toga, Arthur W; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van den Heuvel, Martijn; van der Wee, Nic J; van Eijk, Kristel; van Erp, Theo GM; van Haren, Neeltje EM; van 't Ent, Dennis; van Tol, Marie-Jose; Valdes Hernandez, Maria C; Veltman, Dick J; Versace, Amelia; Völzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna M; Weale, Michael E; Weiner, Michael W; Wen, Wei; Westlye, Lars Tjelta; Whalley, Heather C; Whelan, Christopher D; White, Tonya; Winkler, Anderson M; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel P; Thalamuthu, Anbupalam; Schofield, Peter R; Freimer, Nelson B; Lawrence, Natalia S; Drevets, Wayne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. ...

Biological insights from 108 schizophrenia-associated genetic loci

Ripke, Stephan; Neale, B; Corvin, A; Walters, JTR; Farh, KH; Holmans, PA; Lee, P; Bulik-Sullivan, B; Collier, DA; Huang, H; Pers, TH; Agartz, Ingrid; Agerbo, E; Albus, M; Alexander, M; Amin, F; Bacanu, SA; Begemann, M; Belliveau, RA; Bene, J; Bergen, SE; Bevilacqua, E; Bigdeli, TB; Black, DW; Bruggeman, R; Buccola, NG; Buckner, RL; Byerley, W; Cahn, W; Cai, G; Campion, D; Cantor, RM; Carr, VJ; Carrera, N; Catts, SV; Chambert, KD; Chan, RCK; Chen, RYL; Chen, EYH; Cheng, W; Cheung, EFC; Chong, SA; Cloninger, CR; Cohen, D; Cohen, N; Cormican, P; Craddock, N; Crowley, JJ; Curtis, D; Davidson, M; Davis, KL; Degenhardt, F; Del Favero, J; Demontis, D; Dikeos, D; Dinan, T; Djurovic, Srdjan; Donohoe, G; Drapeau, E; Duan, J; Dudbridge, F; Durmishi, N; Eichhammer, P; Eriksson, J; Escott-Price, V; Essioux, L; Fanous, AH; Farrell, MS; Frank, J; Franke, L; Freedman, R; Freimer, NB; Friedl, M; Friedman, JI; Fromer, M; Genovese, G; Georgieva, L; Giegling, I; Giusti-Rodriguez, P; Godard, S; Goldstein, JI; Golimbet, V; Gopal, S; Gratten, J; De Haan, L; Hammer, C; Hamshere, ML; Hansen, M; Hansen, T; Haroutunian, V; Hartmann, AM; Henskens, FA; Herms, S; Hirschhorn, JN; Hoffmann, P; Hofman, A; Hollegaard, MV; Hougaard, DM; Ikeda, M; Joa, Inge; Julia, A; Kahn, RS; Kalaydjieva, L; Karachanak-Yankova, S; Karjalainen, J; Kavanagh, D; Keller, MC; Kennedy, JL; Khrunin, A; Kim, Y; Klovins, J; Knowles, JA; Konte, B; Kucinskas, V; Kucinskiene, ZA; Kuzelova-Ptackova, H; Kahler, AK; Laurent, C; Keong, JLC; Lee, SH; Legge, SE; Lerer, B; Li, M; Li, T; Liang, KY; Lieberman, J; Limborska, S; Loughland, CM; Lubinski, J; Lonnqvist, J; Macek, M; Magnusson, PKE; Maher, BS; Maier, W; Mallet, J; Marsal, S; Mattheisen, M; Mattingsdal, Morten; McCarley, RW; McDonald, C; McIntosh, AM; Meier, S; Meijer, CJ; Melegh, B; Melle, Ingrid; Mesholam-Gately, RI; Metspalu, A; Michie, PT; Milani, L; Milanova, V; Mokrab, Y; Morris, DW; Mors, O; Murphy, KC; Murray, RM; Myin-Germeys, I; Muller-Myhsok, B; Nelis, M; Nenadic, I; Nertney, DA; Nestadt, G; Nicodemus, KK; Nikitina-Zake, L; Nisenbaum, L; Nordin, A; O'Callaghan, E; O'Dushlaine, C; O'Neill, FA; Oh, SY; Olincy, A; Olsen, L; Van Os, J; Pantelis, C; Papadimitriou, GN; Papiol, S; Parkhomenko, E; Pato, MT; Paunio, T; Pejovic-Milovancevic, M; Perkins, DO; Pietilainen, O; Pimm, J; Pocklington, AJ; Powell, J; Price, A; Pulver, AE; Purcell, SM; Quested, D; Rasmussen, HB; Reichenberg, A; Reimers, MA; Richards, AL; Roffman, JL; Roussos, P; Ruderfer, DM; Salomaa, V; Sanders, AR; Schall, U; Schubert, CR; Schulze, TG; Schwab, SG; Scolnick, EM; Scott, RJ; Seidman, LJ; Shi, J; Sigurdsson, E; Silagadze, T; Silverman, JM; Sim, K; Slominsky, P; Smoller, JW; So, HC; Spencer, CCA; Stahl, EA; Stefansson, H; Steinberg, S; Stogmann, E; Straub, RE; Strengman, E; Strohmaier, J; Stroup, TS; Subramaniam, M; Suvisaari, J; Svrakic, DM; Szatkiewicz, JP; Soderman, E; Thirumalai, S; Toncheva, D; Tosato, S; Veijola, J; Waddington, J; Walsh, D; Wang, D; Wang, Q; Webb, BT; Weiser, M; Wildenauer, DB; Williams, NM; Williams, S; Witt, SH; Wolen, AR; Wong, EHM; Wormley, BK; Xi, HS; Zai, CC; Zheng, X; Zimprich, F; Wray, NR; Stefansson, K; Visscher, PM; Adolfsson, R; Andreassen, Ole Andreas; Blackwood, DHR; Bramon, E; Buxbaum, JD; Børglum, AD; Cichon, S; Darvasi, A; Domenici, E; Ehrenreich, H; Esko, T; Gejman, PV; Gill, M; Gurling, H; Hultman, CM; Iwata, N; Jablensky, AV; Jönsson, Erik Gunnar; Kendler, KS; Kirov, G; Knight, J; Lencz, T; Levinson, DF; Li, QS; Liu, J; Malhotra, AK; McCarroll, SA; McQuillin, A; Moran, JL; Mortensen, PB; Mowry, BJ; Nothen, MM; Ophoff, RA; Owen, MJ; Palotie, A; Pato, CN; Petryshen, TL; Posthuma, D; Rietschel, M; Riley, BP; Rujescu, D; Sham, PC; Sklar, P; St Clair, D; Weinberger, DR; Wendland, JR; Werge, T; Daly, MJ; Sullivan, PF; O'Donovan, MC (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide association studies. Here we report a ...

Common variant at 16p11.2 conferring risk of psychosis

Steinberg, Stacy; de Jong, S; Mattheisen, M; Costas, J; Demontis, D; Jamain, S; Pietilainen, OPH; Lin, K; Papiol, S; Huttenlocher, J; Sigurdsson, E; Vassos, E; Giegling, I; Breuer, R; Fraser, G; Walker, N; Melle, Ingrid; Djurovic, Srdjan; Agartz, Ingrid; Tuulio-Henriksson, A; Suvisaari, J; Lonnqvist, J; Paunio, T; Olsen, L; Hansen, T; Ingason, A; Pirinen, M; Strengman, E; Hougaard, DM; Orntoft, T; Didriksen, M; Hollegaard, MV; Nordentoft, M; Abramova, L; Kaleda, V; Arrojo, M; Sanjuan, J; Arango, C; Etain, B; Bellivier, F; Meary, A; Schurhoff, F; Szoke, A; Ribolsi, M; Magni, V; Siracusano, A; Sperling, S; Rossner, M; Christiansen, C; Kiemeney, LA; Franke, B; van den Berg, LH; Veldink, J; Curran, S; Bolton, P; Poot, M; Staal, W; Rehnstrom, K; Kilpinen, H; Freitag, CM; Meyer, J; Magnusson, P; Saemundsen, E; Martsenkovsky, I; Bikshaieva, I; Martsenkovska, I; Vashchenko, O; Raleva, M; Paketchieva, K; Stefanovski, B; Durmishi, N; Milovancevic, MP; Tosevski, DL; Silagadze, T; Naneishvili, N; Mikeladze, N; Surguladze, S; Vincent, JB; Farmer, A; Mitchell, PB; Wright, A; Schofield, PR; Fullerton, JM; Montgomery, GW; Martin, NG; Rubino, IA; van Winkel, R; Kenis, G; De Hert, M; Rethelyi, JM; Bitter, I; Terenius, L; Jonsson, EG; Bakker, S; van Os, J; Jablensky, A; Leboyer, M; Bramon, E; Powell, J; Murray, R; Corvin, A; Gill, M; Morris, D; O'Neill, FA; Kendler, K; Riley, B; Craddock, N; Owen, MJ; O'Donovan, MC; Thorsteinsdottir, U; Kong, A; Ehrenreich, H; Carracedo, A; Golimbet, V; Andreassen, Ole Andreas; Borglum, AD; Mors, O; Mortensen, PB; Werge, T; Ophoff, RA; Nothen, MM; Rietschel, M; Cichon, S; Ruggeri, M; Tosato, S; Palotie, A; St Clair, D; Rujescu, D; Collier, DA; Stefansson, H; Stefánsson, Kári (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as many as 18 206 ...

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