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Association between genetic variation in the oxytocin receptor gene and emotional withdrawal, but not between oxytocin pathway genes and diagnosis in psychotic disorders

Haram, Marit; Tesli, Martin Steen; Bettella, Franscesco; Djurovic, Srdjan; Andreassen, Ole Andreas; Melle, Ingrid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)

Social dysfunction is common in patients with psychotic disorders. Oxytocin is a neuropeptide with a central role in social behavior. This study aims to explore the relationship between oxytocin pathway genes and symptoms ...

The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data

Thompson, Paul M; Stein, Jason L; Medland, Sarah E; Hibar, Derrek P; Vasquez, Alejandro Arias; Renteria, Miguel E; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J; Martin, Nicholas G; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C; Andreassen, Ole Andreas; Apostolova, Liana G; Appel, Katja; Armstrong, Nicola J; Aribisala, Benjamin; Bastin, Mark E; Bauer, Michael; Bearden, Carrie E; Bergmann, Ørjan; Binder, Elisabeth B; Blangero, John; Bockholt, Henry J; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret I; Booth, Tom; Bowman, Ian J; Bralten, Janita; Brouwer, Rachel M; Brunner, Han G; Brohawn, David G; Buckner, Randy L; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R; Calhoun, Vince D; Cannon, Dara M; Cantor, Rita M; Carless, Melanie A; Caseras, Xavier; Cavalleri, Gianpiero L; Chakravarty, M Mallar; Chang, Kiki D; Ching, Christopher RK; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E; Czisch, Michael; Deary, Ian J; de Geus, Eco JC; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D; Ehrlich, Stefan; Ekman, Carl Johan; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernandez, Guillen; Fisher, Simon E; Foroud, Tatiana; Fox, Peter T; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C; Godlewska, Beata; Goldstein, Rita Z; Gollub, Randy L; Grabe, Hans J; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel E; Gur, Ruben C; Göring, Harald HH; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey B; Hall, Jeremy; Hardy, John; Hartman, Catharina A; Hass, Johanna; Hatton, Sean N; Haukvik, Unn Kristin H.; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian B; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter J; Hollinshead, Marisa; Holmes, Avram J; Homuth, Georg; Hoogman, Martine; Hong, LElliot; Hosten, Norbert; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E; Hwang, Kristy S; Jack Jr, Clifford R; Jenkinson, Mark; Johnston, Caroline; Jönsson, Erik Gunnar; Kahn, Rene S; Kasperaviciute, Dalia; Kelly, Sinead; Kim, Sungeun; Kochunov, Peter; Koenders, Laura; Krämer, Bernd; Kwok, John BJ; Lagopoulos, Jim; Laje, Gonzalo; Landen, Mikael; Landman, Bennett A; Lauriello, John; Lawrie, Stephen M; Lee, Phil H; Le Hellard, Stephanie; Lemaitre, Herve; Leonardo, Cassandra D; Li, Chiang-shan; Liberg, Benny; Liewald, David C; Liu, Xinmin; Lopez, Lorna M; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise WJ; MacQueen, Glenda M; Malt, Ulrik Fredrik; Mandl, Rene; Manoach, Dara S; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen A; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; McIntosh, Andrew M; McMahon, Francis J; McMahon, Katie L; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant W; Morris, Derek W; Moses, Eric K; Mueller, Bryon A; Munoz Maniega, Susana; Muhleisen, Thomas W; Muller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas E; Nilsson, Lars-Göran; Nugent, Allison C; Nyberg, Lars; Olvera, Rene L; Oosterlaan, Jaap; Ophoff, Roel A; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey D; Penninx, Brenda W; Peterson, Charles P; Pfennig, Andrea; Phillips, Mary; Pike, GBruce; Poline, Jean-Baptiste; Potkin, Steven G; Putz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon L; Roffman, Joshua L; Roiz-Santianez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma J; Royle, Natalie A; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder S; Salami, Alireza; Satterthwaite, Theodore D; Savitz, Jonathan; Saykin, Andrew J; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo G; Schork, Andrew J; Schulz, SCharles; Schur, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody M; Simmons, Andrew; Sisodiya, Sanjay M; Smith, Colin; Smoller, Jordan W; Soares, Jair C; Sponheim, Scott R; Sprooten, Emma; Starr, John M; Steen, Vidar Martin; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Sämann, Philipp G; Teumer, Alexander; Toga, Arthur W; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van den Heuvel, Martijn; van der Wee, Nic J; van Eijk, Kristel; van Erp, Theo GM; van Haren, Neeltje EM; van 't Ent, Dennis; van Tol, Marie-Jose; Valdes Hernandez, Maria C; Veltman, Dick J; Versace, Amelia; Völzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna M; Weale, Michael E; Weiner, Michael W; Wen, Wei; Westlye, Lars Tjelta; Whalley, Heather C; Whelan, Christopher D; White, Tonya; Winkler, Anderson M; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel P; Thalamuthu, Anbupalam; Schofield, Peter R; Freimer, Nelson B; Lawrence, Natalia S; Drevets, Wayne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. ...

The role of clusterin in amyloid-β-associated neurodegeneration

Desikan, RS; Thompson, WK; Holland, D; Hess, CP; Brewer, JP; Zetterberg, H; Blennow, K; Andreassen, Ole Andreas; McEvoy, LK; Hyman, BT; Dale, AM (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

Importance Converging evidence indicates that clusterin, a chaperone glycoprotein, influences Alzheimer disease neurodegeneration. However, the precise role of clusterin in Alzheimer disease pathogenesis is still not well ...

Biological insights from 108 schizophrenia-associated genetic loci

Ripke, Stephan; Neale, B; Corvin, A; Walters, JTR; Farh, KH; Holmans, PA; Lee, P; Bulik-Sullivan, B; Collier, DA; Huang, H; Pers, TH; Agartz, Ingrid; Agerbo, E; Albus, M; Alexander, M; Amin, F; Bacanu, SA; Begemann, M; Belliveau, RA; Bene, J; Bergen, SE; Bevilacqua, E; Bigdeli, TB; Black, DW; Bruggeman, R; Buccola, NG; Buckner, RL; Byerley, W; Cahn, W; Cai, G; Campion, D; Cantor, RM; Carr, VJ; Carrera, N; Catts, SV; Chambert, KD; Chan, RCK; Chen, RYL; Chen, EYH; Cheng, W; Cheung, EFC; Chong, SA; Cloninger, CR; Cohen, D; Cohen, N; Cormican, P; Craddock, N; Crowley, JJ; Curtis, D; Davidson, M; Davis, KL; Degenhardt, F; Del Favero, J; Demontis, D; Dikeos, D; Dinan, T; Djurovic, Srdjan; Donohoe, G; Drapeau, E; Duan, J; Dudbridge, F; Durmishi, N; Eichhammer, P; Eriksson, J; Escott-Price, V; Essioux, L; Fanous, AH; Farrell, MS; Frank, J; Franke, L; Freedman, R; Freimer, NB; Friedl, M; Friedman, JI; Fromer, M; Genovese, G; Georgieva, L; Giegling, I; Giusti-Rodriguez, P; Godard, S; Goldstein, JI; Golimbet, V; Gopal, S; Gratten, J; De Haan, L; Hammer, C; Hamshere, ML; Hansen, M; Hansen, T; Haroutunian, V; Hartmann, AM; Henskens, FA; Herms, S; Hirschhorn, JN; Hoffmann, P; Hofman, A; Hollegaard, MV; Hougaard, DM; Ikeda, M; Joa, Inge; Julia, A; Kahn, RS; Kalaydjieva, L; Karachanak-Yankova, S; Karjalainen, J; Kavanagh, D; Keller, MC; Kennedy, JL; Khrunin, A; Kim, Y; Klovins, J; Knowles, JA; Konte, B; Kucinskas, V; Kucinskiene, ZA; Kuzelova-Ptackova, H; Kahler, AK; Laurent, C; Keong, JLC; Lee, SH; Legge, SE; Lerer, B; Li, M; Li, T; Liang, KY; Lieberman, J; Limborska, S; Loughland, CM; Lubinski, J; Lonnqvist, J; Macek, M; Magnusson, PKE; Maher, BS; Maier, W; Mallet, J; Marsal, S; Mattheisen, M; Mattingsdal, Morten; McCarley, RW; McDonald, C; McIntosh, AM; Meier, S; Meijer, CJ; Melegh, B; Melle, Ingrid; Mesholam-Gately, RI; Metspalu, A; Michie, PT; Milani, L; Milanova, V; Mokrab, Y; Morris, DW; Mors, O; Murphy, KC; Murray, RM; Myin-Germeys, I; Muller-Myhsok, B; Nelis, M; Nenadic, I; Nertney, DA; Nestadt, G; Nicodemus, KK; Nikitina-Zake, L; Nisenbaum, L; Nordin, A; O'Callaghan, E; O'Dushlaine, C; O'Neill, FA; Oh, SY; Olincy, A; Olsen, L; Van Os, J; Pantelis, C; Papadimitriou, GN; Papiol, S; Parkhomenko, E; Pato, MT; Paunio, T; Pejovic-Milovancevic, M; Perkins, DO; Pietilainen, O; Pimm, J; Pocklington, AJ; Powell, J; Price, A; Pulver, AE; Purcell, SM; Quested, D; Rasmussen, HB; Reichenberg, A; Reimers, MA; Richards, AL; Roffman, JL; Roussos, P; Ruderfer, DM; Salomaa, V; Sanders, AR; Schall, U; Schubert, CR; Schulze, TG; Schwab, SG; Scolnick, EM; Scott, RJ; Seidman, LJ; Shi, J; Sigurdsson, E; Silagadze, T; Silverman, JM; Sim, K; Slominsky, P; Smoller, JW; So, HC; Spencer, CCA; Stahl, EA; Stefansson, H; Steinberg, S; Stogmann, E; Straub, RE; Strengman, E; Strohmaier, J; Stroup, TS; Subramaniam, M; Suvisaari, J; Svrakic, DM; Szatkiewicz, JP; Soderman, E; Thirumalai, S; Toncheva, D; Tosato, S; Veijola, J; Waddington, J; Walsh, D; Wang, D; Wang, Q; Webb, BT; Weiser, M; Wildenauer, DB; Williams, NM; Williams, S; Witt, SH; Wolen, AR; Wong, EHM; Wormley, BK; Xi, HS; Zai, CC; Zheng, X; Zimprich, F; Wray, NR; Stefansson, K; Visscher, PM; Adolfsson, R; Andreassen, Ole Andreas; Blackwood, DHR; Bramon, E; Buxbaum, JD; Børglum, AD; Cichon, S; Darvasi, A; Domenici, E; Ehrenreich, H; Esko, T; Gejman, PV; Gill, M; Gurling, H; Hultman, CM; Iwata, N; Jablensky, AV; Jönsson, Erik Gunnar; Kendler, KS; Kirov, G; Knight, J; Lencz, T; Levinson, DF; Li, QS; Liu, J; Malhotra, AK; McCarroll, SA; McQuillin, A; Moran, JL; Mortensen, PB; Mowry, BJ; Nothen, MM; Ophoff, RA; Owen, MJ; Palotie, A; Pato, CN; Petryshen, TL; Posthuma, D; Rietschel, M; Riley, BP; Rujescu, D; Sham, PC; Sklar, P; St Clair, D; Weinberger, DR; Wendland, JR; Werge, T; Daly, MJ; Sullivan, PF; O'Donovan, MC (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide association studies. Here we report a ...

Common variant at 16p11.2 conferring risk of psychosis

Steinberg, Stacy; de Jong, S; Mattheisen, M; Costas, J; Demontis, D; Jamain, S; Pietilainen, OPH; Lin, K; Papiol, S; Huttenlocher, J; Sigurdsson, E; Vassos, E; Giegling, I; Breuer, R; Fraser, G; Walker, N; Melle, Ingrid; Djurovic, Srdjan; Agartz, Ingrid; Tuulio-Henriksson, A; Suvisaari, J; Lonnqvist, J; Paunio, T; Olsen, L; Hansen, T; Ingason, A; Pirinen, M; Strengman, E; Hougaard, DM; Orntoft, T; Didriksen, M; Hollegaard, MV; Nordentoft, M; Abramova, L; Kaleda, V; Arrojo, M; Sanjuan, J; Arango, C; Etain, B; Bellivier, F; Meary, A; Schurhoff, F; Szoke, A; Ribolsi, M; Magni, V; Siracusano, A; Sperling, S; Rossner, M; Christiansen, C; Kiemeney, LA; Franke, B; van den Berg, LH; Veldink, J; Curran, S; Bolton, P; Poot, M; Staal, W; Rehnstrom, K; Kilpinen, H; Freitag, CM; Meyer, J; Magnusson, P; Saemundsen, E; Martsenkovsky, I; Bikshaieva, I; Martsenkovska, I; Vashchenko, O; Raleva, M; Paketchieva, K; Stefanovski, B; Durmishi, N; Milovancevic, MP; Tosevski, DL; Silagadze, T; Naneishvili, N; Mikeladze, N; Surguladze, S; Vincent, JB; Farmer, A; Mitchell, PB; Wright, A; Schofield, PR; Fullerton, JM; Montgomery, GW; Martin, NG; Rubino, IA; van Winkel, R; Kenis, G; De Hert, M; Rethelyi, JM; Bitter, I; Terenius, L; Jonsson, EG; Bakker, S; van Os, J; Jablensky, A; Leboyer, M; Bramon, E; Powell, J; Murray, R; Corvin, A; Gill, M; Morris, D; O'Neill, FA; Kendler, K; Riley, B; Craddock, N; Owen, MJ; O'Donovan, MC; Thorsteinsdottir, U; Kong, A; Ehrenreich, H; Carracedo, A; Golimbet, V; Andreassen, Ole Andreas; Borglum, AD; Mors, O; Mortensen, PB; Werge, T; Ophoff, RA; Nothen, MM; Rietschel, M; Cichon, S; Ruggeri, M; Tosato, S; Palotie, A; St Clair, D; Rujescu, D; Collier, DA; Stefansson, H; Stefánsson, Kári (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as many as 18 206 ...

A genome-wide association study of anorexia nervosa

Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy; Andreassen, Ole Andreas; Espeseth, Thomas; Lundervold, Astri; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie; Mattingsdal, Morten; Boraske, V; Franklin, CS; Floyd, James A. B.; Thornton, Laura M; Huckins, L. M.; Southam, L; Rayner, NW; Tachmazidou, I; Klump, KL; Treasure, Jim; Lewis, C. M.; Schmidt, U; Tozzi, F; Kiezebrink, K; Hebebrand, J.; Gorwood, P.; Adan, R. A. H.; Kas, M. J. H.; Favaro, A; Santonastaso, P; Fernández-Aranda, Fernando; Gratacòs, Mònica; Rybakowski, Finn; Dmitrzak-Weglarz, M.; Kaprio, J; Keski-Rahkonen, A; Raevuori, A.; Van Furth, E. F.; Slof-Op 't Landt, M. C. T.; Hudson, JI; Monteleone, P.; Kaplan, AS; Karwautz, A; Hakonarson, H; Berrettini, W. H.; Guo, Y; Li, D; Schork, NJ; Komaki, G; Ando, T; Inoko, H. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome-wide association study (GWAS) have yielded significant and ...

Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: A report from the Cognitive Genomics consorTium (COGENT)

Lencz, T; Knowles, Emily; Davies, G; Guha, S; Liewald, DC; Starr, JM; Djurovic, Srdjan; Melle, Ingrid; Sundet, Kjetil Søren; Christoforou, Andrea; Reinvang, Ivar; Mukherjee, Sayan; Derosse, P; Lundervold, Arvid; Steen, Vidar Martin; Espeseth, Thomas; John, M.; Räikkönen, K; Widen, E; Palotie, A; Eriksson, JG; Giegling, I; Konte, B; Ikeda, M; Roussos, P; Giakoumaki, S; Burdick, KE; Payton, A.; Ollier, W; Horan, M.; Donohoe, G; Morris, D; Corvin, A; Gill, M; Pendleton, N; Iwata, N; Darvasi, A; Bitsios, P; Rujescu, D; Lahti, J; Le Hellard, Stephanie; Keller, MC; Andreassen, Ole Andreas; Deary, IJ; Glahn, DC; Malhotra, AK (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)

It has long been recognized that generalized deficits in cognitive ability represent a core component of schizophrenia (SCZ), evident before full illness onset and independent of medication. The possibility of genetic ...

Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder

Haukvik, Unn Kristin H.; McNeil, Thomas; Lange, Elisabeth; Melle, Ingrid; Dale, AM; Andreassen, Ole Andreas; Agartz, Ingrid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)

Background Pre- and perinatal adversities may increase the risk for schizophrenia and bipolar disorder. Hypoxia-related obstetric complications (OCs) are associated with brain anatomical abnormalities in schizophrenia, but ...

Association analysis between suicidal behaviour and candidate genes of bipolar disorder and schizophrenia

Finseth, Per Ivar; Sønderby, Ida Elken; Djurovic, Srdjan; Agartz, Ingrid; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Andreassen, Ole Andreas; Vaaler, Arne Einar; Tesli, Martin Steen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)

Background The present study investigated associations between the strongest joint genetic risk variants for bipolar disorder (BD) and schizophrenia (SCZ) and a history of suicide attempt in patients with BD, SCZ and related ...

Increased amygdala and visual cortex activity and functional connectivity towards stimulus novelty is associated with state anxiety

Ousdal, Olga Therese; Andreassen, Ole Andreas; Server, Andres; Jensen, Jimmy Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)

Novel stimuli often require a rapid reallocation of sensory processing resources to determine the significance of the event, and the appropriate behavioral response. Both the amygdala and the visual cortex are central ...

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