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Now showing items 1-10 of 11
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background: Results showing that sera from double vaccinated individuals have minimal neutralizing activity against Omicron have been interpreted as indicating the need for a third vaccine dose for protection. However, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background
Based on their essential role in concerting immunological and inflammatory responses we hypothesized that the homeostatic chemokines CCL19 and CCL21 may play a pathogenic role in rickettsiae ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Aim Cardiac inflammation is important in the pathogenesis of heart failure. However, the consequence of systemic inflammation on concomitant established heart failure, and in particular diastolic heart failure, is less ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background: Obesity is an increasingly prevalent metabolic disorder in the modern world and is associated with structural and functional changes in the heart. The NLRP3 inflammasome is an innate immune sensor that can be ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Aim. Inflammation is important in heart failure (HF). The role of the immune receptor toll-like receptor 9 (TLR9) in HF is not understood and not investigated in diastolic HF. We investigated the role of TLR9 in a murine ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2022)
Background: Although coronavirus disease 2019 (COVID-19) is primarily a respiratory infection, mounting evidence suggests that the gastrointestinal (GI) tract is involved in the disease, with gut barrier dysfunction and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Purpose
Triglycerides (TG) and their major transport lipoprotein in the circulation (VLDL) appear to be related to inflammation. Patients with common variable immunodeficiency (CVID) have ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The aetiology of thoracic aortic aneurysm (TAA) is largely unknown, but inflammation is likely to play a central role in the pathogenesis. In this present study, we aim to investigate the complement receptors in TAA.Aortic ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Metabolic and immune systems are among the most fundamental requirements for survival. Many metabolic and immune response pathways or nutrient- and pathogen-sensing systems are evolutionarily conserved throughout species. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Obesity-related diseases (e.g. type 2 diabetes mellitus and cardiovascular disorders) represent an increasing health problem worldwide. NLRP3 inflammasome activation may underlie obesity-induced inflammation and ...