Browsing Institutt for klinisk medisin by Author "Yaddehi Gamage, Thilini Hansamali Gamage"

Now showing items 1-1 of 1

  • STIM1 R304W causes muscle degeneration and impaired platelet activation in mice 
    Yaddehi Gamage, Thilini Hansamali Gamage; Gunnes, Gjermund; Lee, Robert Hugh; Louch, William Edward; Holmgren, Asbjørn; Bruton, Joseph D.; Lengle, Emma; Kolstad, Terje R Selnes; Revold, Tobias; Amundsen, Silja Svanstrøm; Dalen, Knut Tomas; Holme, Pål Andre; Tjønnfjord, Geir Erland; Christensen, Geir Arve; Westerblad, Håkan; Klungland, Arne; Bergmeier, Wolfgang; Misceo, Doriana; Frengen, Eirik (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    STIM1 and ORAI1 regulate store-operated Ca2+ entry (SOCE) in most cell types, and mutations in these proteins have deleterious and diverse effects. We established a mouse line expressing the STIM1 R304 W gain-of-function ...