Browsing Institutt for klinisk medisin by Author "Haaf, Thomas"

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  • Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals 
    Haertle, Larissa; Maierhofer, Anna; Bock, Julia; Lehnen, Harald; Böttcher, Yvonne; Blüher, Matthias; Schorsch, Martin; Potabattula, Ramya; El Hajj, Nady; Appenzeller, Silke; Haaf, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Imprinted genes show parent-specific activity (functional haploidy), which makes them particularly vulnerable to epigenetic dysregulation. Here we studied the methylation profiles of oppositely imprinted genes at single ...