The c-Myb transcription factor is a key regulator of haematopoiesis. Its activity is regulated by a large network of protein interactions and post-translational modifications. ATF7IP is a transcriptional cofactor previously ...

Lyme borreliosis (LB) is the most frequent human tick-borne disease in Scandinavia. This master thesis is focusing on the Borrelia burgdorferi sensu lato (s.l.) complex, which is the causative agent of LB. Today, the B. ...

Protein methylation is a post-translational modification best studied in regards to histones and the histone code. In recent years, more studies have begun to unearth non-histone protein methylation, in most cases however, ...

Transcription of genes is controlled by a highly tuned machinery regulated by transcription factors, histone modifications and chromatin remodelers. CHD3, as a member of the chromatin remodelers, has an important role in ...

Chondroitin Sulfate (CS) glycosaminoglycan (GAG) is a modification carried by proteoglycans (PGs) that have important physiological functions in cartilage and bone formation, the immune system and the central nervous system. ...

It is known that elderly people suffering from heart disease can have memory problems. The hippocampus is the part of the brain that is essential for memory formation and is one of the areas that is most vulnerable to ...

Abstract The conserved oligomeric Golgi (COG) complex is a hetero-octameric complex involved in retrograde transport of Golgi resident enzymes along the secretory pathway. Its presumed function is in the tethering of ...

Staphylococcus epidermidis has developed from a skin and mucus commensal to an opportunistic pathogen, and is frequently causing infections in medical implants. Its ability to form biofilm on implant surfaces makes these ...

The formation of the pre-RC is an important event during DNA replication initiation. It occurs from late M phase until early G1 phase and is required to license the replication origin before the binding of other initiation ...