Browsing Molekylærbiologi by Title
Now showing items 1-20 of 186
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Aberrant m6A regulation in Alkbh5 deficient mice results in increased DNA methylation and altered gene expressionRestricted Access (Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2014)
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(Master thesis / Masteroppgave, 2014)Staphylococcus epidermidis has developed from a skin and mucus commensal to an opportunistic pathogen, and is frequently causing infections in medical implants. Its ability to form biofilm on implant surfaces makes these ...
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(Master thesis / Masteroppgave, 2013)Cytokinesis is the final step of cell division that leads to the physical separation of two daughter cells by abscission. It is now well established that several components of endosomal machineries are involved in cytokinesis ...
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AlkB homologs in metazoans – an applied bioinformatics and experimental DNA/RNA repair studyRestricted Access (Master thesis / Masteroppgave, 2015)Abstract E. coli AlkB protein was discovered three decades ago and is known to be involved in direct damage reversal of methylation lesions in DNA and RNA through oxidative demethylation. The protein belongs to the superfamily ...
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An investigation of the functional role of the MADS-box γ and MADS-box α type I transcription factors: AGAMOUS-LIKE 28 and AGAMOUS-LIKE 36Restricted Access (Master thesis / Masteroppgave, 2014)
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Analysis of the role of four members of the NEDD4 family of E3 ubiquitin ligases in the modulation of growth characteristics of LoVo colon cancer cellsRestricted Access (Master thesis / Masteroppgave, 2017)
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Atg8 Proteins in Autophagy and Death Receptor-Induced Apoptosis in Prostate Cancer CellsRestricted Access (Master thesis / Masteroppgave, 2015)Autophagy and apoptosis are two important cellular processes, whose dysfunctions are involved in many severe diseases, including cancer. Bulk autophagy is typically mediated by the sequestration of cytoplasmic material ...
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(Master thesis / Masteroppgave, 2014)Lungekreft representerer den hyppigste årsaken til kreft-dødsfall i Norge. Ikke-småcellet lungekreft (NSCLC) er den viktigste under typen av lungekreft. Det er ca 2500 pasienter diagnostisert med NSCLC og 2100 dødsfall i ...
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(Master thesis / Masteroppgave, 2013)The Casitas B-lineage lymphoma (Cbl) family of ubiquitin ligases has been studied for years regarding their important role in downregulation of ligand bound epidermal growth factor receptor (EGFR). The two isoforms c-Cbl ...
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(Master thesis / Masteroppgave, 2015)
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CD4+ TH-cell epitope discovery by combinatorial phage display of MHC class II A proof of principle studyRestricted Access (Master thesis / Masteroppgave, 2014)The interaction between a CD4+ TH cell and an antigen presenting cell (APC) is a finely tuned event in adaptive immunity. The affinity is dictated by the T cell receptor (TCR) and the characteristics of antigenic peptide ...
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(Master thesis / Masteroppgave, 2014)The formation of the pre-RC is an important event during DNA replication initiation. It occurs from late M phase until early G1 phase and is required to license the replication origin before the binding of other initiation ...
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(Master thesis / Masteroppgave, 2018)In recent years, environmental concerns and global temperature increase has attracted a wide interest. Global temperature has increased in the recent years, and will continue to do so in the near future. How organisms, ...
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(Master thesis / Masteroppgave, 2014)
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(Master thesis / Masteroppgave, 2015)
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(Master thesis / Masteroppgave, 2018)Purpose: The purpose and aim of this project was to investigate immune contexture according to tumour molecular subtype, and ER status. To find the interrelationship between serum cytokine levels and specific tumour cell ...
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(Master thesis / Masteroppgave, 2013)Prostate cancer (PCa) is the most common type of cancer among men in Western countries. An approach to better PCa diagnosis, prognosis and management is to identify genes that are prostate-specific and differentially ...
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Characterization and in vitro differentiation of iPS cells to investigate DNA glycosylase Neil3Restricted Access (Master thesis / Masteroppgave, 2015)DNA glycosylases play an important role in DNA repair, keeping at bay the accumulation of DNA damage. Neil3 has been shown to be a functional DNA glycosylase in vitro with a proliferative tissue-specific expression, highly ...
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(Master thesis / Masteroppgave, 2017)Methylation is the transfer of a methyl group from a methyl donor to a substrate, and such reactions are catalyzed by enzymes called methyltransferases (MTases). The methyl donor for cellular methylation reactions is most ...