Now showing items 1147-1166 of 1310

  • McAdam, Stephen N.; Fleckenstein, Burkhard; Rasmussen, Ingunn B; Sandlie, Inger; Bogen, Bjarne; Vinter, N.J.; Sollid, Ludvig Magne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)
    Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to I-A(k) in different conformations. ...
  • Tørresen, Ole K.; Star, Bastiaan; Mier, Pablo; Andrade-Navarro, Miguel A.; Bateman, Alex; Jarnot, Patryk; Gruca, Aleksandra; Grynberg, Marcin; Kajava, Andrey V.; Promponas, Vasilis J.; Anisimova, Maria; Jakobsen, Kjetill Sigurd; Linke, Dirk (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for sequencing, genome assembly, and automated annotation of genes and proteins. This ...
  • Norum, Jens Henrik; Skarpen, Ellen; Brech, Andreas; Kuiper, Raoul; Waaler, Jo; Krauss, Stefan; Sørlie, Therese (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: The WNT pathway regulates intestinal stem cells and is frequently disrupted in intestinal adenomas. The pathway contains several potential biotargets for interference, including the poly-ADP ribosyltransferase ...
  • Hauge, Sissel (Doctoral thesis / Doktoravhandling, 2020)
    Targeting the DNA damage response to selectively kill cancer cells is a topic of great interest in the field of cancer research. Inhibitors of the cell cycle checkpoint kinases WEE1, CHK1 and ATR have been developed, and ...
  • Vikan, Aurora Karlsen (Master thesis / Masteroppgave, 2019)
  • Wu, Hua; Chen, Yuyuan; Li, Bin; Li, Chun; Guo, Jun; You, Jia; Hu, Xian; Kuang, Dong; Qi, Shibo; Pin, Liu; Li, Lei; Xu, Chuanrui (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Background Rho-Associated kinases ROCK1 and ROCK2 have been extensively investigated in the pathogenesis of cardiovascular disease. However, their roles are not fully understood in carcinogenesis. In this study, we ...
  • Høydahl, Lene Støkken; Frick, Rahel; Sandlie, Inger; Løset, Geir Åge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Monoclonal antibodies (mAbs) are valuable as research reagents, in diagnosis and in therapy. Their high specificity, the ease in production, favorable biophysical properties and the opportunity to engineer different ...
  • Dahal-Koirala, Shiva; Risnes, Louise Fremgaard; Christophersen, Asbjørn; Sarna, Vikas Kumar; Lundin, Knut Erik Aslaksen; Sollid, Ludvig Magne; Qiao, Shuo Wang (Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)
    CD4+ T cells recognizing dietary gluten epitopes in the context of disease-associated human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 molecules are the key players in celiac disease pathogenesis. Here, we conducted a large-scale ...
  • Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Risnes, Louise Fremgaard; Dahal-Koirala, Shiva; Neumann, Ralf Stefan; Bergseng, Elin; Frigstad, Terje; Frick, Rahel; du Pré, Marie Fleur; Dalhus, Bjørn; Lundin, Knut Erik Aslaksen; Qiao, Shuo Wang; Sollid, Ludvig Magne; Sandlie, Inger; Løset, Geir Åge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Selection of biased T cell receptor (TCR) repertoires across individuals is seen in both infectious diseases and autoimmunity, but the underlying molecular basis leading to these shared repertoires remains unclear. Celiac ...
  • Kaarbø, Mari; Storm, Margrethe; Qu, Su; Wæhre, Haakon; Risberg, Bjørn Åke; Danielsen, Håvard Emil; Saatcioglu, Fahri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    TCTP has been implicated in a plethora of important cellular processes related to cell growth, cell cycle progression, malignant transformation and inhibition of apoptosis. In addition to these intracellular functions, ...
  • Andersen, Guri Sogn; Foldager Pedersen, Morten; Nielsen, Søren L. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2013)
    Kelps, seaweeds and seagrasses provide important ecosystem services in coastal areas, and loss of these macrophytes is a global concern. Recent surveys have documented severe declines in populations of the dominant kelp ...
  • Freitas, Carla; Olsen, Esben Moland; Knutsen, Halvor; Albretsen, Jon; Moland, Even (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    1. Habitat selection is a complex process, which involves behavioural decisions guided by the multiple needs and constraints faced by individuals. Climate-induced changes in environmental conditions may alter those trade-offs ...
  • Mutinova, Petra Thea; Kulichova, Jana; Ugland, Karl Inne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    This study was conducted to simultaneously investigate the spatial and temporal dynamics of diatom communities inhabiting two microhabitat types (Sphagnum periphyton and epipelon) in a peatland area of the Czech Republic. ...
  • Valseth, Karoline; Nesbø, Camilla L; Easterday, W. R; Turner, Wendy C; Olsen, Jaran S; Stenseth, Nils C; Haverkamp, Thomas H A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Anthrax is a globally distributed disease affecting primarily herbivorous mammals. It is caused by the soil-dwelling and spore-forming bacterium Bacillus anthracis. The dormant B. anthracis spores ...
  • Durant, Joel Marcel; Skern-Mauritzen, Mette; Krasnov, Yuri V.; Nikolaeva, Natalia G.; Lindstrøm, Ulf; Dolgov, Andrey V. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The Barents Sea system is often depicted as a simple food web in terms of number of dominant feeding links. The most conspicuous feeding link is between the Northeast Arctic cod Gadus morhua, the world's largest cod stock ...
  • Hertel, Anne Gabriela; Zedrosser, Andreas; Mysterud, Atle; Støen, Ole-Gunnar; Steyaert, Sam; Swenson, Jon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Avoiding predators most often entails a food cost. For the Scandinavian brown bear (Ursus arctos), the hunting season coincides with the period of hyperphagia. Hunting mortality risk is not uniformly distributed throughout ...
  • Qviller, Lars; Grøva, Lise; Viljugrein, Hildegunn; Klingen, Ingeborg; Mysterud, Atle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background: Climate change can affect the activity and distribution of species, including pathogens and parasites. The densities and distribution range of the sheep tick (Ixodes ricinus) and it’s transmitted pathogens ...
  • Aasebø, Ida E. J.; Lepperød, Mikkel Elle; Stavrinou, Maria; Nøkkevangen, Sandra; Einevoll, Gaute; Hafting, Torkel; Fyhn, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The activity pattern and temporal dynamics within and between neuron ensembles are essential features of information processing and believed to be profoundly affected by anesthesia. Much of our general understanding of ...
  • Poste, Amanda; Hoel, Cathrine Skaar; Andersen, Tom; Arts, Michael T.; Færøvig, Per-Johan; Borgå, Katrine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Increases in terrestrial organic matter (tOM) transport from catchments to boreal lakes can affect methylmercury (MeHg) accumulation in aquatic biota both directly by increasing concentrations of aqueous MeHg, and indirectly ...