Now showing items 21-40 of 1596

  • Fagerland, Morten W; Lydersen, Stian; Laake, Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Statistical methods that use the mid-p approach are useful tools to analyze categorical data, particularly for small and moderate sample sizes. Mid-p tests strike a balance between overly ...
  • de Muinck, Eric J; Lagesen, Karin; Afset, Jan E; Didelot, Xavier; Rønningen, Kjersti S; Rudi, Knut; Stenseth, Nils C; Trosvik, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Despite being one of the most intensely studied model organisms, many questions still remain about the evolutionary biology and ecology of Escherichia coli. An important step toward achieving a ...
  • Sikkeland, Jørgen; Saatcioglu, Fahri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Six transmembrane protein of prostate (Stamp) proteins play an important role in prostate cancer cell growth. Recently, we found that Stamp2 has a critical role in the integration of inflammatory and metabolic signals in ...
  • Kuijjer, Marieke L; Peterse, Elisabeth F; van den Akker, Brendy E; Briaire-de Bruijn, Inge H; Serra, Massimo; Meza-Zepeda, Leonardo A; Myklebost, Ola; Hassan, A B; Hogendoorn, Pancras C; Cleton-Jansen, Anne-Marie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background High-grade osteosarcoma is an aggressive tumor most often developing in the long bones of adolescents, with a second peak in the 5th decade of life. Better knowledge on cellular signaling in this ...
  • Mobraten, Kaia; Haug, Trude M; Kleiveland, Charlotte R; Lea, Tor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Omega-3 PUFAs are known to have anti-inflammatory properties, and different mechanisms are involved. GPR120 is a G-protein coupled receptor that has recently received attention because of its ...
  • Andersen, Guri Sogn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    The lack of recovery in Norwegian populations of the kelp Saccharina latissima (Linnaeus) C. E. Lane, C. Mayes, Druehl & G. W. Saunders after a large-scale disturbance that occurred sometime between the late 1990s and early ...
  • Hunsicker, Mary E.; Ciannelli, L; Bailey, Kevin M.; Zador, Stephani; Stige, Leif Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    There is growing evidence that climate and anthropogenic influences on marine ecosystems are largely manifested by changes in species spatial dynamics. However, less is known about how shifts in species distributions might ...
  • Backström, Niclas; Sætre, Glenn-Peter; Ellegren, Hans (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Inference of population and species histories and population stratification using genetic data is important for discriminating between different speciation scenarios and for correct interpretation ...
  • Riyahi, Sepand; Hammer, Øyvind; Arbabi, Tayebeh; Sánchez, Antonio; Roselaar, Cees S; Aliabadian, Mansour; Sætre, Glenn-Peter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background The granivorous house sparrow Passer domesticus is thought to have developed its commensal relationship with humans with the rise of agriculture in the Middle East some 10,000 years ago, and to ...
  • Lyons, Andrew J; Turner, Wendy C; Getz, Wayne M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Advances in GPS technology have created both opportunities in ecology as well as a need for analytical tools that can deal with the growing volume of data and ancillary variables associated with ...
  • Star, Bastiaan; Haverkamp, Thomas H; Jentoft, Sissel; Jakobsen, Kjetill S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background The observation that specific members of the microbial intestinal community can be shared among vertebrate hosts has promoted the concept of a core microbiota whose composition is determined by ...
  • Gregis, Veronica; Andrés, Fernando; Sessa, Alice; Guerra, Rosalinda F; Simonini, Sara; Mateos, Julieta L; Torti, Stefano; Zambelli, Federico; Prazzoli, Gian M; Bjerkan, Katrine N; Grini, Paul E; Pavesi, Giulio; Colombo, Lucia; Coupland, George; Kater, Martin M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background MADS-domain transcription factors play important roles during plant development. The Arabidopsis MADS-box gene SHORT VEGETATIVE PHASE (SVP) is a key regulator of two developmental phases. It ...
  • Mora, Antonio; Michalickova, Katerina; Donaldson, Ian M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Multigenic diseases are often associated with protein complexes or interactions involved in the same pathway. We wanted to estimate to what extent this is true given a consolidated protein ...
  • de Muinck, Eric Jacques (Doctoral thesis / Doktoravhandling, 2013)
    This work is a deep characterization of Escherichia coli (E.coli) colonization of a cohort of infants and their mothers in Trondheim, Norway. E.coli cause ~2 million deaths due to infant diarrhea and ~150 million cases of ...
  • Cui, Yinqiu; Li, Hongjie; Ning, Chao; Zhang, Ye; Chen, Lu; Zhao, Xin; Hagelberg, Erika; Zhou, Hui (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background The West Liao River valley in Northeast China is an ecologically diverse region, populated in prehistory by human populations with a wide range of cultures and modes of subsistence. To help ...
  • Andersen, Jan Terje; Cameron, J; Plumridge, A; Sleep, D; Evans, L; Sandlie, Inger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Albumin has a serum half-life of 3 weeks in humans. This has been utilized to extend the serum persistence of biopharmaceuticals that are fused to albumin. In light of the fact that the neonatal Fc receptor (FcRn) is a key ...
  • Gunnarsen, Kristin Støen; Kristinsson, Solveig Gunn; Justesen, Sune; Frigstad, Terje; Buus, Søren; Bogen, Bjarne; Sandlie, Inger; Løset, Geir Åge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    We here report a novel phage display selection strategy enabling fast and easy selection of thermostabilized proteins. The approach is illustrated with stabilization of an aggregation-prone soluble single chain T cell ...
  • Andersen, Jan Terje; Gonzalez-Pajuelo, Maria; Foss, Stian; Landsverk, Ole J. B.; Pinto, Debora; Szyroki, Alexander; de Haard, Hans J.; Saunders, Michael; Vanlandschoot, Peter; Sandlie, Inger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    FcRn is a key player in several immunological and non-immunological processes, as it mediates maternal-fetal transfer of IgG, regulates the serum persistence of IgG and albumin, and transports both ligands between different ...
  • Harbeck, Michaela; Seifert, Lisa; Hänsch, Stephanie; Wagner, David; Birdsell, Dawn; Parise, Katy L.; Wiechmann, Ingrid; Grupe, Gisela; Thomas, Astrid; Keim, Paul; Zöller, Lothar; Bramanti, Barbara; Riehm, Julia; Scholz, Holger C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Yersinia pestis, the etiologic agent of the disease plague, has been implicated in three historical pandemics. These include the third pandemic of the 19th and 20th centuries, during which plague was spread around the ...
  • Røhr, Åsmund Kjendseth; Hammerstad, Marta; Andersson, K. Kristoffer (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Thioredoxin-like proteins contain a characteristic C-x-x-C active site motif and are involved in a large number of biological processes ranging from electron transfer, cellular red-ox level maintenance, and regulation of ...