Browsing Institutt for biovitenskap by Title
Now showing items 109-128 of 2884
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AlkB homologs in metazoans – an applied bioinformatics and experimental DNA/RNA repair studyRestricted Access (Master thesis / Masteroppgave, 2015)Abstract E. coli AlkB protein was discovered three decades ago and is known to be involved in direct damage reversal of methylation lesions in DNA and RNA through oxidative demethylation. The protein belongs to the superfamily ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)ABSTRACT Establishment of the pluripotency regulatory network in somatic cells by introducing four transcription factors [octamer binding transcription factor 4 (OCT4; also known as POU5F1), sex determining region ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Polycyclic aromatic compounds (PACs) and metals are important contaminants in road runoff. Vital mitigation measures against aquatic contamination from road runoff include the use of sedimentation ponds. However, it has ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract Glycosylation of multiple proteins via O-linkage is well documented in bacterial species of Neisseria of import to human disease. Recent studies of protein glycosylation (pgl) gene distribution established ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Freshwater colonization by threespine stickleback has led to divergence in morphology between ancestral marine and derived freshwater populations, making them ideal for studying natural selection on phenotypes. In an open ...
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Allopatric speciation and multi-trait variation in the common chaffinch (Fringilla coelebs) complex (Master thesis / Masteroppgave, 2013)The common chaffinch (Fringilla coelebs) is a widespread passerine species in the West Palearctic, and is a common breeder in most of Europe, western Asia, northern Africa, and the Macaronesian islands in the Atlantic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Among the major unresolved questions in ecosystem evolution are whether coevolving multispecies communities are dominated more by biotic or by abiotic factors, and whether evolutionary stasis affects performance as well ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Genome-wide association studies have implicated many ion channels in schizophrenia pathophysiology. Although the functions of these channels are relatively well characterized by single-cell studies, the contributions of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Studies on the consequences of ocean acidification for the marine ecosystem have revealed behavioural changes in coral reef fishes exposed to sustained near-future CO2 levels. The changes have been linked to altered function ...
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(Journal article / Tidsskriftartikkel; Peer reviewed, 2019)Puwainaphycins (PUWs) and minutissamides (MINs) are structurally analogous cyclic lipopeptides possessing cytotoxic activity. Both types of compound exhibit high structural variability, particularly in the fatty acid (FA) ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)KRAS mutation is a well‐known marker for poor response to targeted treatment and patient prognosis in microsatellite stable (MSS) colorectal cancer (CRC). However, variation in clinical outcomes among patients wild‐type ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)Many plant and animal species are changing their latitudinal and/or altitudinal distributions in response to climate change, but whether fungi show similar changes is largely unknown. Here, we use historical fungal fruit ...
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Amyloid-beta treated organotypic hippocampal slices as a model system of Alzheimer´s diseaseRestricted Access (Master thesis / Masteroppgave, 2022)
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(Master thesis / Masteroppgave, 2022)The accumulation of pathogenic amyloid proteins is a common theme of many neurodegenerative diseases, including Alzheimer's disease, the most common form of dementia. One of the main hallmarks of the disease is the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Genomic assignment tests can provide important diagnostic biological characteristics, such as population of origin or ecotype. Yet, assignment tests often rely on moderate- to high-coverage sequence data that can be difficult ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Individual trait variation is essential for populations to cope with multiple stressors and continuously changing environments. The immense number of possible stressor combinations and the influence of phenotypic variation ...
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(Master thesis / Masteroppgave, 2017)In Antarctica, the failure to establish international agreement on regulations caused an overexploitation which reduced the number of blue whales from about 240 000 to less than 500. I have here taken a closer look at the ...
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(Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2021)Isobaric peptide termini labeling (IPTL) is an approach for quantitative proteomics based on crosswise isotopic labeling of peptides at the N- and C-terminus. The labeling reagents are chosen in isotopic variations that ...
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(Master thesis / Masteroppgave, 2022)Red helleborine (Cephalanthera rubra) is an endangered orchid in Norway. The Norwegian populations are part of the northernmost distribution of red helleborine and has been given a prioritized status in Norway, to ensure ...