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The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy 
Jonsson, Maria Karolina; Hensvold, Aase Haj; Hansson, Monika; Aga, Anna-Birgitte; Sexton, Joseph; Mathsson-Alm, Linda; Cornillet, Martin; Serre, Guy; Lillegraven, Siri; Fevang, Bjørg-Tilde Svanes; Catrina, Anca Irinel; Haavardsholm, Espen A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background: Anti-citrullinated protein antibody (ACPA) reactivities precede clinical onset of rheumatoid arthritis (RA), and it has been suggested that ACPA reactivities towards distinct target proteins may be associated ...
Efficient parameter estimation enables the prediction of drug response using a mechanistic pan-cancer pathway model 
Fröhlich, Fabian; Kessler, Thomas; Weindl, Daniel; Shadrin, Alexey A.; Schmiester, Leonard; Hache, Hendrik; Muradyan, Artur; Schutte, Moritz; Lim, Ji-Hyun; Heinig, Matthias; Theis, Fabian J.; Lehrach, Hans; Wierling, Christoph; Lange, Bodo; Hasenauer, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Mechanistic models are essential to deepen the understanding of complex diseases at the molecular level. Nowadays, high-throughput molecular and phenotypic characterizations are possible, but the integration of such data ...
Proteomic analysis of Zika virus infected primary human fetal neural progenitors suggests a role for doublecortin in the pathological consequences of infection in the cortex 
Jiang, Xuan; Dong, Xiao; Li, Shi-Hua; Zhou, Yue-Peng; Rayner, Simon; Xia, Hui-Min; Gao, George F.; Yuan, Hui; Tang, Ya-Ping; Luo, Min-Hua (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Zika virus (ZIKV) infection is associated with severe neurological defects in fetuses and newborns, such as microcephaly. However, the underlying mechanisms remain to be elucidated. In this study, proteomic analysis on ...
Defining and categorizing outcomes of Moral Case Deliberation (MCD): concept mapping with experienced MCD participants 
De Snoo Trimp, Janine; Molewijk, Albert Christiaan; De Vet, Henrica CW (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background: To support healthcare professionals in dealing with ethically difficult situations, Clinical Ethics Support (CES) services like Moral Case Deliberation (MCD) are increasingly implemented. To assess the impact ...
Polypectomy techniques among gastroenterologists in Norway – a nationwide survey 
Pedersen, Ina Borgenheim; Løberg, Magnus; Hoff, Geir; Kalager, Mette; Bretthauer, Michael; Holme, Øyvind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background and study aims Incomplete polyp removal has been estimated to cause 27 % of all colorectal cancers detected soon after colonoscopy. There is limited information regarding polypectomy techniques among endoscopists. ...
The molecular basis for specificity at the level of the protein kinase a catalytic subunit 
Søberg, Kristoffer; Skålhegg, Bjørn Steen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Assembly of multi enzyme complexes at subcellular localizations by anchoring- and scaffolding proteins represents a pivotal mechanism for achieving spatiotemporal regulation of cellular signaling after hormone receptor ...
Fecal microbiota transplantation for primary Clostridium difficile infection 
Juul, Frederik Emil; Garborg, Kjetil Kjeldstad; Bretthauer, Michael; Skudal, Hilde Kristin; Oines, Mari N.; Wiig, Håvard; Rose, Øystein; Seip, Birgitte Karen Berggreen; Thomas Lamont, J.; Midtvedt, Tore; Valeur, Jørgen; Kalager, Mette; Holme, Øyvind; Helsingen, Lise M.; Løberg, Magnus; Adami, Hans Olov (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
ESCRTs in membrane sealing 
Radulovic, Maja; Stenmark, Harald (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
The multisubunit endosomal sorting complex required for transport (ESCRT) machinery is a key regulator of cellular membrane dynamics. Initially characterized in the budding yeast Saccharomyces cerevisiae for its involvement ...
Spectroscopy of 25,65/67Mn: Strong coupling in the N = 40 "island of inversion" 
Liu, XY; Liu, Zhong; Ding, B; Doornenbal, P; Obertelli, A; Lenzi, SM; Walker, PM; Chung, LX; Linh, BD; Authelet, G; Baba, H; Calvet, D; Chateau, F; Corsi, A; Delbart, A; Gheller, JM; Gillibert, A; Isobe, T; Lapoux, V; Matsushita, M; Momiyama, S; Motobayashi, T; Niikura, M; Nowacki, F; Otsu, H; Péron, C; Peyaud, A; Pollacco, EC; Roussé, JY; Sakurai, H; Sasano, M; Shiga, Y; Takeuchi, S; Taniuchi, R; Uesaka, T; Wang, H; Yoneda, K; Lam, YH; Huang, TH; Sun, MD; Zhang, WQ; Lu, HY; Hou, DS; Browne, F; Dombradi, Zs; Franchoo, S; Giacoppo, Francesca; Gottardo, A; Hadynska-Klek, Katarzyna; Korkulu, Z; Koyama, S; Kubota, Y; Lee, J; Lettmann, M; Lozeva, R; Matsui, K; Miyazaki, T; Nishimura, S; Louchart, C; Olivier, L; Ota, S; Patel, Z; Sahin, Eda; Santamaria, C; Shand, C; Söderstrom, PA; Stefan, GL; Steppenbeck, D; Sumikama, T; Suzuki, D; Vajta, Zs; Werner, V; Wu, J; Xu, Z; Zhou, XH; Zhang, YH; Xu, HS; Zhang, FS (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Excited states in 63,65,67Mn were studied via in-beam γ -ray spectroscopy following knockout reactions from 68Fe. Similar level schemes, consisting of the 11/2−, 9/2−, 7/2− and 5/2− g.s. level sequence, connected by I → I ...
Relaxation to equilibrium and EOS in ultra-relativistic heavy-ion collisions 
Zabrodin, Evgeny; Bravina, Larissa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
We study relaxation to equilibrium of hot and dense hadron-string matter produced in the central zone of central heavy-ion collisions at energies 11.6AGeV ≤ Elab ≤ 160AGeV. Two microscopic transport models, UrQMD and QGSM, ...
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