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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Once activated, the intracellular receptor NLRP3 assembles an inflammasome protein complex that facilitates the caspase-1-mediated maturation of IL-1β and IL-18. Inactive NLRP3 is guarded by a protein complex containing ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Purpose: The cornea is continually exposed to highly energetic solar UV-B (280-320 nm). Our aim was to investigate whether UV-B triggers the activation of NLRP3 inflammasomes and the production of IL-1β and/or IL-18 in ...