Now showing items 4454-4473 of 12637

  • Hadjineophytou, Chris; Anonsen, Jan Haug; Wang, Nelson; Ma, Kevin; Viburiene, Raimonda; Vik, Åshild; Harrison, Odile B; Maiden, Martin CJ; Grad, Yonatan H.; Koomey, John Michael (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The human pathogens N. gonorrhoeae and N. meningitidis display robust intra- and interstrain glycan diversity associated with their O-linked protein glycosylation (pgl) systems. In an effort to better understand the evolution ...
  • Norderhaug, K. M.; Angles d'Auriac, M. B.; Fagerli, C. W.; Gundersen, H.; Christie, H.; Dahl, K.; Hobæk, A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    We compared the genetic differentiation in the green sea urchin Strongylocentrotus droebachiensis from discrete populations on the NE Atlantic coast. By using eight recently developed microsatellite markers, genetic structure ...
  • Devor, Anna; Andreassen, Ole Andreas; Wang, Yunpeng; Mäki-Marttunen, Tuomo; Smeland, Olav Bjerkehagen; Fan, Chun Chieh; Schork, Andrew J.; Holland, Dominic; Thompson, Wesley Kurt; Witoelar, Aree; Chen, Chi-Hua; Desikan, Rahul S.; McEvoy, Linda K.; Djurovic, Srdjan; Greengard, Paul; Svenningsson, Per; Einevoll, Gaute; Dale, Anders (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    The most recent genome-wide association studies (GWAS) of schizophrenia (SCZ) identified hundreds of risk variants potentially implicated in the disease. Further, novel statistical methodology designed for polygenic ...
  • Olsen, Ingar; Chen, Tsute; Tribble, Gena D (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Porphyromonas gingivalis is considered a keystone pathogen in adult periodontitis but has also been associated with systemic diseases. It has a myriad of virulence factors that differ between strains. Genetic exchange and ...
  • Chen, Haitao; Ewing, Charles M; Zheng, Sigun; Grindedaal, Eli M; Cooney, Kathleen A.; Djurovic, Srdjan; Andreassen, Ole Andreas; Axcrona, Karol; Mills, Ian Geoffrey; Xu, Jianfeng; Mæhle, Lovise Olaug; Fossa, Sophie D.; Isaacs, William B. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Norway has one of the highest rates of death due to prostate cancer (PCa) in the world. To assess the contribution of both common and rare single nucleotide variants (SNPs) to the prostate cancer burden in Norway, we ...
  • Evankow, Ann; Christie, Hartvig C; Hancke, Kasper; Brysting, Anne Krag; Junge, Claudia; Fredriksen, Stein; Thaulow, Jens (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Knowledge of genetic diversity among wild populations is becoming increasingly important as more species are recognized for their bioeconomic value. Industrialization of natural resources, such as kelp in the marine shallow ...
  • Drange, Ole Kristian; Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Finseth, Per Ivar; Witoelar, Aree; Frei, Oleksandr; Psychiatric Genomic Consortium, Bipolar Disorder Working Group; Wang, Yunpeng; Hassani, Sahar; Srdjan, Djurovic; Dale, Anders; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background: Alzheimer’s disease (AD) and bipolar disorder (BIP) are complex traits influenced by numerous common genetic variants, most of which remain to be detected. Clinical and epidemiological evidence suggest that AD ...
  • Haddeland, Peter Jørgen Tønnessen; Junge, Claudia; Serbezov, Dimitar; Vøllestad, Leif Asbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Knowing the breeding system of a species is important in order to understand individual variation in reproductive success. Large variation in reproductive success and thus reproductive skew strongly impacts on the effective ...
  • Andreassen, Ole Andreas; Harbo, Hanne Flinstad; Wang, Yunpeng; Thompson, WK; Schork, AJ; Mattingsdal, Morten; Zuber, Verena; Bettella, Franscesco; Ripke, S; Kelsoe, JR; Kendler, KS; O'Donovan, MC; Sklar, P; McEvoy, LK; Desikan, RS; Lie, Benedicte Alexandra; Djurovic, Srdjan; Dale, Anders M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Converging evidence implicates immune abnormalities in schizophrenia (SCZ), and recent genome-wide association studies (GWAS) have identified immune-related single-nucleotide polymorphisms (SNPs) associated with SCZ. Using ...
  • Vrbanec, Jurica; Lederer-Dembic, Petra; Bulat-Kardum, Ljiljana; Balen, Sanja; Eftedal, Randi Krog; Dembic, Zlatko (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Regarding genetic predisposition to tuberculosis, we suggest that the maximal risk for clinical manifestation requires complementation of sub-risks divided among the hallmarks of the disease. Clinical tuberculosis would ...
  • Reppe, Sjur; Wang, Yunpeng; Thompson, WK; McEvoy, LK; Schork, AJ; Zuber, Verena; LeBlanc, Marissa; Bettella, Franscesco; Mills, Ian Geoffrey; Desikan, Rahul S.; Djurovic, Srdjan; Gautvik, Kaare M; Dale, AM; Andreassen, Ole Andreas; GEFOS, Consortium (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, ...
  • Wondimu, Tigist; Gizaw, Abel; Tusiime, Felly Mugizi; Masao, Catherine; Abdi, Ahmed Abdikhadir; Hou, Yan; Nemomissa, Sileshi; Brochmann, Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The scattered eastern African high mountains harbor a renowned and highly endemic flora, but the taxonomy and phylogeographic history of many plant groups are still insufficiently known. The high-alpine populations of the ...
  • Bjerkan, Katrine; Hornslien, Karina Stensland; Johannessen, Ida Marie; Krabberød, Anders Kristian; van Ekelenburg, Yuri Stephan; Kalantarian, Maryam; Shirzadi, Reza; Comai, Luca; Brysting, Anne Krag; Bramsiepe, Jonathan; Grini, Paul Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Genomic imprinting regulates parent‐specific transcript dosage during seed development and is mainly confined to the endosperm. Elucidation of the function of many imprinted genes has been hampered by the lack of corresponding ...
  • Stokowy, Tomasz; Polushina, Tatiana; Sønderby, Ida Elken; Karlsson, Robert; Giddaluru, Sudheer; Le Hellard, Stephanie; Bergen, Sarah E; Sullivan, Patrick F; Andreassen, Ole Andreas; Djurovic, Srdjan; Hultman, Christina M.; Steen, Vidar Martin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Schizophrenia is a serious psychotic disorder with high heritability. Several common genetic variants, rare copy number variants and ultra-rare gene-disrupting mutations have been linked to disease susceptibility, but there ...
  • Kambur, Oleg; Kaunisto, Mari A; Winsvold, Bendik K S; Wilsgaard, Tom; Stubhaug, Audun; Zwart, John-Anker; Kalso, Eija; Nielsen, Christopher Sivert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    P2X7 is a nonselective cation channel activated by extracellular ATP. P2X7 activation contributes to the proinflammatory response to injury or bacterial invasion and mediates apoptosis. Recently, P2X7 function has been ...
  • Rohde, Kerstin; Keller, Maria; La Cour Poulsen, Lars; Blüher, Matthias; Kovacs, Peter; Böttcher, Yvonne (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Obesity is among the most threatening health burdens worldwide and its prevalence has markedly increased over the last decades. Obesity maybe considered a heritable trait. Identifications of rare cases of monogenic obesity ...
  • Gustafsson, A Lovisa S; Skrede, Inger; Rowe, Heather C.; Gussarova, Galina; Borgen, Liv; Rieseberg, Loren; Brochmann, Christian; Parisod, Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Crossing experiments indicate that hybrid sterility barriers frequently have developed within diploid, circumpolar plant species of the genus Draba. To gain insight into the rapid evolution of postzygotic reproductive ...
  • Cole, John W.; Kanse, Sandip; Authors, Other; Mitchell, Braxton (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background and purpose Polymorphisms in coagulation genes have been associated with early-onset ischemic stroke. Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the ...
  • Røysamb, Espen; Nes, Ragnhild Bang; Czajkowski, Nikolai Olavi; Vassend, Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Human wellbeing is influenced by personality traits, in particular neuroticism and extraversion. Little is known about which facets that drive these associations, and the role of genes and environments. Our aim was to ...
  • Skage, Morten; Barth, Julia Maria Isis; Jentoft, Sissel; Øverli, Øyvind; Jakobsen, Kjetill Sigurd (Research report / Forskningsrapport / PublishedVersion, 2017)
    Formålet med denne undersøkelsen var å identifisere mulige krysninger mellom hund og ulv i dagens skandinaviske ulvebestand. I tillegg ønsket vi å finne ut i hvor stor grad det er mulig å gjenkjenne innblanding av hund i ...