Background Vacc-4x, a Gag p24-based therapeutic HIV vaccine, has been shown to reduce viral load set-points after intradermal administration. In this randomized controlled pilot study we investigate intranasal administration ...

Natural killer (NK) cells hold potential as a source of allogeneic cytotoxic effector cells for chimeric antigen receptor (CAR)-mediated therapies. Here, we explored the feasibility of transfecting CAR-encoding mRNA into ...

The gut absorbs dietary nutrients and provides a barrier to xenobiotics and microbiome metabolites. To cope with toxin exposures, the intestinal epithelium is one of the most rapidly proliferating tissues in the body. The ...

This paper argues that the common practice of benchmarking is inadequate as a scientific evaluation methodology. It further attempts to introduce the empirical tradition of the physical sciences by using techniques from ...

The idea for this little dossier spécial emerged from a workshop, held in Berlin in December 2016 to discuss the possibilities of fundraising for projects related to the study of the etymology of Arabic. The workshop came ...

In this introduction, we aim to demystify the concept of wealth, too entangled in financial discourses, which have generally reduced it to ‘accumulated assets’. This is at odds with the intricate cultural history of wealth ...

The climate research community uses atmospheric reanalysis data sets to understand a wide range of processes and variability in the atmosphere, yet different reanalyses may give very different results for the same diagnostics. ...

This introduction provides an overview and analysis of key scientific data regarding air pollution in China. It constitutes a reference for understanding how policymakers, media and population in China make sense of and ...