Now showing items 3064-3083 of 13470

  • Gill, Peter; Hicks, Tacha; Butler, John M.; Connolly, Ed; Gusmão, Leonor; Kokshoorn, Bas; Morling, Niels; H van Oorschot, Roland A; Parson, Walther; Prinz, Mechthild; Schneider, Peter M.; Sijen, Titia; Taylor, Duncan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The value of the evidence depends critically on propositions. In the second of two papers intended to provide advice to the community on difficult aspects of evaluation and the formulation of propositions, we focus primarily ...
  • Gill, Peter; Hicks, Tacha; Butler, John M.; Connolly, Ed; Gusmão, Leonor; Kokshoorn, Bas; Morling, Niels; van Oorschot, Roland A.H.; Parson, Walther; Prinz, Mechthild; Schneider, Peter M.; Sijen, Titia; Taylor, Duncan (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    The interpretation of evidence continues to be one of the biggest challenges facing the forensic community. This is the first of two papers intended to provide advice on difficult aspects of evaluation and in particular ...
  • Hylland, Ketil; Skei, Bjørn Borge; Brunborg, Gunnar; Lang, Thomas; Gubbins, Matthew J.; Le Goff, Jérémie; Burgeot, Thierry (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Dab (Limanda limanda) and haddock (Melanogrammus aeglefinus) were collected from coastal and offshore locations in the Baltic (dab only), North Sea (haddock from one location only) and Iceland. Blood was analysed for DNA ...
  • Gill, Peter (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    DNA analysis has revolutionised forensic science; helping to catch prolific murderers and shining a light on miscarriages of justice that have seen innocent people wrongfully convicted of serious crimes. Such is the power ...
  • de Boer, Hugo; Ghorbani, Abdolbaset; Manzanilla, Vincent; Raclariu, Ancuta Cristina; Kreziou, Anna; Ounjai, Sarawut; Osathanunkul, Maslin; Gravendeel, Barbara (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    In eastern Mediterranean countries orchids continue to be collected from the wild for the production of salep, a beverage made of dried orchid tubers. In this study we used nrITS1 and nrITS2 DNA metabarcoding to identify ...
  • Mewicha, Berihun Gebremedhin; Flagstad, Øystein; Bekele, Afework; Gelete, Desalegn Chala; Bakkestuen, Vegar; Boessenkool, Sanne; Popp, Magnus; Gusarova, Galina; Schrøder-Nielsen, Audun; Nemomissa, Sileshi; Brochmann, Christian; Stenseth, Nils Christian; Epp, Laura (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Human population expansion and associated degradation of the habitat of many wildlife species cause loss of biodiversity and species extinctions. The small Simen Mountains National Park in Ethiopia is one of the last ...
  • Kular, Lara; Liu, Yun; Ruhrmann, Sabrina; Zheleznyakova, Galina; Marabita, Francesco; Gomez-Cabrero, David; James, Tojo; Ewing, Ewoud; Lindén, Magdalena; Górnikiewicz, Bartosz; Aeinehband, Shahin; Stridh, Pernilla; Link, Jenny; Andlauer, Till F.M.; Gasperi, Christiane; Wiendl, Heinz; Zipp, Frauke; Gold, Ralf; Tackenberg, Björn; Weber, Frank; Hemmer, Bernhard; Strauch, Konstantin; Heilmann-Heimbach, Stefanie; Rawal, Rajesh; Schminke, Ulf; Schmidt, Carsten O.; Kacprowski, Tim; Franke, Andre; Laudes, Matthias; Dilthey, Alexander T.; Celius, Elisabeth Gulowsen; Søndergaard, Helle Bach; Tegnér, Jesper; Harbo, Hanne Flinstad; Oturai, Annette B.; Olafsson, Sigurgeir; Eggertsson, Hannes P.; Halldorsson, Bjarni V.; Hjaltason, Haukur; Olafsson, Elias; Jonsdottir, Ingileif; Stefansson, Kari; Olsson, Tomas; Piehl, Fredrik; Ekström, Tomas J.; Kockum, Ingrid; Feinberg, Andrew P.; Jagodic, Maja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    The human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated and predominantly expressed in monocytes among carriers of ...
  • Fleischer, Thomas; Mathelier, Anthony (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Breast cancers exhibit genome-wide aberrant DNA methylation patterns. To investigate how these affect the transcriptome and which changes are linked to transformation or progression, we apply genome-wide expression–methylation ...
  • Fleischer, Thomas; Tekpli, Xavier; Mathelier, Anthony; Wang, Shixiong; Nebdal, Daniel J.H.; Dhakal, Hari Prasad; Sahlberg, Kristine Kleivi; Schlichting, Ellen; Børresen-Dale, Anne-Lise; Borgen, Elin; Naume, Bjørn; Eskeland, Ragnhild; Frigessi, Arnoldo; Tost, Jörg; Rodriguez, Antoni Hurtado; Kristensen, Vessela N. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Breast cancers exhibit genome-wide aberrant DNA methylation patterns. To investigate how these affect the transcriptome and which changes are linked to transformation or progression, we apply genome-wide expression–methylation ...
  • Wikenius, Ellen; Moe, Vibeke; Smith, Lars; Heiervang, Einar; Berglund, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Infants undergo extensive developments during their frst year of life. Although the biological mechanisms involved are not yet fully understood, changes in the DNA methylation in mammals are believed to play a key role. ...
  • Xu, Cheng-Jian; Söderhäll, Cilla; Bustamante, Mariona; Baïz, Nour; Gruzieva, Olena; Gehring, Ulrike; Mason, Dan; Chatzi, Leda; Basterrechea, Mikel; Llop, Sabrina; Torrent, Maties; Forastiere, Francesco; Fantini, Maria Pia; Carlsen, Karin C. Lødrup; Haahtela, Tari; Morin, Andréanne; Kerkhof, Marjan; Merid, Simon Kebede; van Rijkom, Bianca; Jankipersadsing, Soesma A.; Bonder, Marc Jan; Ballereau, Stephane; Vermeulen, Cornelis J.; Aguirre-Gamboa, Raul; De Jongste, Johan C.; Smit, Henriëtte A.; Kumar, Ashish; Pershagen, Göran; Guerra, Stefano; Garcia-Aymerich, Judith; Greco, Dario; Reinius, Lovisa; McEachan, Rosemary R.C.; Azad, Raf; Hovland, Vegard; Mowinckel, Petter; Alenius, Harri; Fyhrquist, Nanna; Lemonnier, Nathanael; Pellet, Johann; Auffray, Charles; van der Vlies, Pieter; van Diemen, Cleo C.; Li, Yang; Wijmenga, Cisca; Netea, Mihai G.; Moffatt, Miriam F.; Cookson, William O.C.M; Anto, Josep M.; Bousquet, Jean; Laatikainen, Tiina; Laprise, Catherine; Carlsen, Kai-Håkon; Gori, Davide; Porta, Daniela; Iñiguez, Carmen; Bilbao, Jose Ramon; Kogevinas, Manolis; Wright, John; Brunekreef, Bert; Kere, Juha; Nawijn, Martijn C.; Annesi-Maesano, Isabella; Sunyer, Jordi; Melén, Erik; Koppelman, Gerard H. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Background DNA methylation profiles associated with childhood asthma might provide novel insights into disease pathogenesis. We did an epigenome-wide association study to assess methylation profiles associated with ...
  • Guo, Yichen; Zhang, Ruyang; Shen, Sipeng; Wei, Yongyue; Salama, Sebastian Moran; Fleischer, Thomas; Bjaanæs, Maria Moksnes; Karlsson, Anna; Planck, Maria; Su, Li; Zhu, Zhaozhong; Staaf, Johan; Helland, Åslaug; Esteller, Manel; Christiani, David C. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Background: Previous studies support a tumor-suppressor role for LRRC3B across various types of cancers. We aimed to investigate the association between DNA methylation of LRRC3B and overall survival (OS) for patients with ...
  • Keller, Maria; Klos, Matthias; Rohde, Kerstin; Krüger, Jacqueline; Kurze, Tabea; Dietrich, Arne; Schön, Michael R.; Gärtner, Daniel; Lohmann, Tobias; Dressler, Miriam; Stumvoll, Michael; Bluher, Matthias; Kovacs, Peter; Böttcher, Yvonne (Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)
    DNA methylation is a crucial epigenetic mechanism in obesity and fat distribution. We explored the Sarcospan (SSPN) gene locus by using genome-wide data sets comprising methylation and expression data, pyrosequencing ...
  • Narud, Birgitte; Stenseth, Else-Berit; Johannisson, Anders; Myromslien, Frøydis Deinboll; Gaustad, Ann Helen; Wilson, Robert Charles; Lyle, Robert; Morrell, Jane; Kommisrud, Elisabeth; Ahmad, Rafi (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Sperm DNA integrity is considered essential for successful transmission of the paternal genome, fertilization and normal embryo development. DNA fragmentation index (DFI, %) has become a key parameter in the ...
  • Njølstad, Tormund Salvesen; Trovik, Jone; Hveem, Tarjei Sveinsgjerd; Kjæreng, Marna Lill; Kildal, Wanja; Pradhan, Manohar; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Haugland, Hans Kristian; Eraker, Runar; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik; Amant, Frédéric; Werner, Henrica Maria Johanna; Salvesen, Helga; Danielsen, Håvard Emil (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
    Background: Preoperative risk stratification is essential in tailoring endometrial cancer treatment, and biomarkers predicting lymph node metastasis and aggressive disease are aspired in clinical practice. DNA ploidy ...
  • Kistenich, Sonja; Halvorsen, Rune; Schrøder-Nielsen, Audun; Thorbek, Birgitte Lisbeth Graae; Timdal, Einar; Bendiksby, Mika (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Biological specimens in natural history collections worldwide are increasingly being used in biogeographical, environmental, and taxonomic studies. For their meaningful use, correct species identification is crucial. For ...
  • Andersen, Tor Kristian; Zhou, Fan; Cox, Rebecca Jane; Bogen, Bjarne; Grødeland, Gunnveig (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Zoonotic influenza H7 viral infections have a case fatality rate of about 40%. Currently, no or limited human to human spread has occurred, but we may be facing a severe pandemic threat if the virus acquires the ability ...
  • Løvås, Tom-Ole; Bruusgaard, Jo C.; Øynebråten, Inger; Gundersen, Kristian; Bogen, Bjarne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Vaccination with naked DNA holds great promise but immunogenicity needs to be improved. DNA constructs encoding bivalent proteins that bind antigen-presenting cells (APC) for delivery of antigen have been shown to enhance ...
  • Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background: Cross-sectional studies suggest associations between abnormal lipid levels and prevalence of low back pain (LBP), but it is not known if there is any causal relationship. Objective: The objective was to ...
  • Teigset, Charlotte; Mohn, Christine; Brunborg, Cathrine; Juuhl-Langseth, Monica; Holmen, Aina; Rund, Bjørn Rishovd (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Background Being in a period with extensive brain maturation, adolescents with early‐onset schizophrenia‐spectrum disorders (EOS) provide unique neurodevelopmental data that may contribute to a better understanding of ...