Browsing CRIStin høstingsarkiv by Title
Now showing items 2841-2860 of 8292
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Pathogenic bacteria continuously encounter multiple forms of stress in their hostile environments, which leads to DNA damage. With the new insight into biology offered by genome sequences, the elucidation of the gene content ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)When plastids are transferred between eukaryote lineages through series of endosymbiosis, their environment changes dramatically. Comparison of dinoflagellate plastids that originated from different algal groups has revealed ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing commercial fisheries and incipient aquaculture. Here we present the genome sequence of Atlantic cod, showing evidence for complex ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Porphyromonas gingivalis is considered a major etiologic agent in adult periodontitis. Gingipains are among its most important virulence factors, but their release is unique in strain HG66. We present the genome sequence ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Despite the major role of genome size for physiology, ecology, and evolution, there is still mixed evidence with regard to proximate and ultimate drivers. The main causes of large genome size are proliferation of noncoding ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background: Attention deficit hyperactivity disorder (ADHD) is a highly heritable neuropsychiatric condition, but it has been difficult to identify genes underlying this disorder. This study aimed to explore genetics of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background & Aims: Liver fibrogenesis – scarring of the liver that can lead to cirrhosis and liver cancer – is characterized by hepatocyte impairment, capillarization of liver sinusoidal endothelial cells (LSECs) and hepatic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)There is considerable variability in the susceptibility of smokers to develop chronic obstructive pulmonary disease (COPD). The only known genetic risk factor is severe deficiency of α1-antitrypsin, which is present in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The volume of the lateral ventricles (LV) increases with age and their abnormal enlargement is a key feature of several neurological and psychiatric diseases. Although lateral ventricular volume is heritable, a comprehensive ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome-wide association study (GWAS) have yielded significant and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Borderline personality disorder (BOR) is determined by environmental and genetic factors, and characterized by affective instability and impulsivity, diagnostic symptoms also observed in manic phases of bipolar disorder ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Brachial circumference (BC), also known as upper arm or mid arm circumference, can be used as an indicator of muscle mass and fat tissue, which are distributed differently in men and women. Analysis of anthropometric ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background: The current epidemic of obesity and associated diseases calls for swift actions to better understand the mechanisms by which genetics and environmental factors affect metabolic health in humans. Monozygotic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Aim: We performed an epigenome-wide association study within the Finnish Health in Teens cohort to identify differential DNA methylation and its association with BMI in adolescents. Materials & methods: Differential DNA ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Sertoli cells have dual roles during the cells’ lifetime. In the juvenile mammal, Sertoli cells proliferate and create the structure of the testis, and during puberty they cease to proliferate and take on the adult role ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Louse-borne relapsing fever was one of the major diseases affecting Western human populations, with its last major pandemic killing millions after World War I. Despite the major role fevers have played in epidemic events ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)A variety of sex determination mechanisms can be observed in evolutionary divergent teleosts. Sex determination is genetic in Atlantic cod (Gadus morhua), however the genomic location or size of its sex-locus is unknown. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Hybridization is increasingly recognized as a potent evolutionary force. Although additive genetic variation and novel combinations of parental genes theoretically increase the potential for hybrid species to adapt, few ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Recent developments in the field of genomics have provided new and powerful insights into population structure and dynamics that are essential for the conservation of biological diversity. As a commercially highly valuable ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Many species, including humans, have emerged via complex reticulate processes involving hybridisation. Under certain circumstances, hybridisation can cause distinct lineages to collapse into a single lineage with an admixed ...