Now showing items 1736-1755 of 11607

  • Jettestuen, Espen; Nermoen, Anders; Hestmark, Geir; Timdal, Einar; Mathiesen, Joachim (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Crustose lichen communities on rocks exhibit fascinating spatial mosaics resembling political maps of nations or municipalities. Although the establishment and development of biological populations are important themes in ...
  • Barratt-Due, Andreas; Fløisand, Yngvar; Lang, Hilde Elisabeth; Kvam, Ann Kristin; Holme, Pål Andre; Bergseth, Grete; Tjønnfjord, Geir Erland; Mollnes, Tom Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Research suggests that the complement system plays a role in the pathophysiology of APS, and experimental studies have revealed a requirement for C5 in APS-induced thrombus formation [1]. However, limited data are available ...
  • Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen; Bergseth, Grete; Nymo, Stig Haugset; Lappegård, Knut Tore; Woodruff, T. M.; Espevik, Terje; Mollnes, Tom Eirik; Brekke, Ole-Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    There is a close cross‐talk between complement, Toll‐like receptors (TLRs) and coagulation. The role of the central complement component 5 (C5) in physiological and pathophysiological hemostasis has not, however, been fully ...
  • Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje; Nilsson, Per; Mollnes, Tom Eirik; Barratt-Due, Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Heme is a critical danger molecule liberated from hemeproteins in various conditions, including from hemoglobin in hemolytic diseases. Heme may cause thromboinflammatory damage by activating inflammatory and hemostatic ...
  • Pischke, Søren Erik; Gustavsen, Alice; Orrem, HL; Egge, Kjetil Hagene; Courivaud, Fredric A A; Fontenelle, Hugues; Despont, Alain; Bongoni, Anjan K.; Rieben, Robert; Tønnessen, Tor Inge; Nunn, Miles A.; Scott, Helge; Skulstad, Helge; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Inhibition of complement factor 5 (C5) reduced myocardial infarction in animal studies, while no benefit was found in clinical studies. Due to lack of cross-reactivity of clinically used C5 antibodies, different inhibitors ...
  • Johansen, Wenche; Grove, Søren; Anonsen, Jan Haug; Moen, Anders; Agusti-Ridaura, Celia; Azar, Amir Sefidmouy; Strætkvern, Knut Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Complement component 5 (C5) is an essential factor of the defensive complement system in all vertebrates. We report the characterization of C5 cDNA and protein from Atlantic salmon (Salmo salar), a teleost fish species of ...
  • Ricklin, Daniel; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Research during past decades made it evident that complement is involved in more tasks than fighting infections, but has important roles in other immune surveillance and housekeeping functions. If the balance between ...
  • Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore; Espevik, Terje; Mollnes, Tom Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Despite recent medical advances, atherosclerosis is a global burden accounting for numerous deaths and hospital admissions. Immune-mediated inflammation is a major component of the atherosclerotic process, but earlier ...
  • Sokołowska, A.; Babul, A.; Mayer, L.; Shen, Sijing; Madau, Piero (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    We use high-resolution cosmological hydrodynamical simulations of Milky-Way-sized galaxies with varying supernova feedback strengths and merger histories to investigate the formation of their gaseous halos and especially ...
  • Khranovskyy, V.; Shtepliuk, I.; Vines, Lasse; Yakimova, R. (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    We have studied the photoluminescence and electrical properties of ZnO films grown epitaxially by atmospheric pressure MOCVD on 4H-SiC substrates. The dominating D°X line on the low temperature PL spectrum is attributed ...
  • Hu, Hua; Roth, Fabian Christoph; Vandael, David; Jonas, Peter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Fast-spiking, parvalbumin-expressing GABAergic interneurons (PV+-BCs) express a complex machinery of rapid signaling mechanisms, including specialized voltage-gated ion channels to generate brief action potentials (APs). ...
  • Silva, Daniel; Rikvold, Per Arne (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The ground states of the general three-state lattice-gas (equivalently, S = 1 Ising) model with nearest-neighbor interactions on a square lattice are explored in the full, five-dimensional parameter space of three interaction ...
  • Taiaroa, George; Samuelsen, Ørjan; Kristensen, Tom; Økstad, Ole Andreas; Heikal, Adam (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Carbapenem-resistant Pseudomonas aeruginosa is defined as a “critical” priority pathogen for the development of new antibiotics. Here we report the complete genome sequence of an extensively drug-resistant, Verona ...
  • Anmarkrud, Jarl Andreas; Lifjeld, Jan Terje (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Natural history museum collections represent a vast source of ancient and historical DNA samples from extinct taxa that can be utilized by high-throughput sequencing tools to reveal novel genetic and phylogenetic information ...
  • Tveten, Gry Merete; Spyrou, A; Schwengner, R; Naqvi, F; Larsen, Ann-Cecilie; Eriksen, Tomas Kvalheim; Bello Garrote, Frank Leonel; Bernstein, LA; Bleuel, DL; Crespo Campo, Lucia; Guttormsen, Magne Sveen; Giacoppo, Francesca; Görgen, Andreas; Hagen, Trine Wiborg; Hadynska-Klek, Katarzyna; Klintefjord, Malin; Meyer, BS; Nyhus, Hilde-Therese; Renstrøm, Therese; Rose, Sunniva Johanne; Sahin, Eda; Siem, Sunniva; Tornyi, Tamas Gabor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    One of the greatest questions for modern physics to address is how elements heavier than iron are created in extreme astrophysical environments. A particularly challenging part of that question is the creation of the ...
  • Berges, Natalia; Nawaz, Meh Sameen; Dahl, Tuva Børresdatter; Hagen, Lars; Bjørås, Magnar; Lærdahl, Jon Kristen; Alseth, Ingrun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Endonuclease V (ENDOV) is a ribonuclease with affinity for inosine which is the deamination product of adenosine. The genomes of most organisms, including human, encode ENDOV homologs, yet knowledge about in vivo functions ...
  • Naliboff, John B.; Buiter, Susanne; Péron-Pinvidic, Gwenn; Osmundsen, Per Terje; Tetreault, Joya (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Rifted margins mark a transition from continents to oceans and contain in their architecture a record of their rift history. Recent investigations of rift architecture have suggested that multiphase deformation of the crust ...
  • Lysdahl, Kristin Bakke; Hofmann, Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Complexity entails methodological challenges in assessing health care interventions. In order to address these challenges, a series of characteristics of complexity have been identified in the Health Technology Assessment ...
  • Astrup, Elisabeth; Lekva, Tove; Davi, Giovanni; Otterdal, Kari; Santilli, Francesca; Øie, Erik; Halvorsen, Bente; Damås, Jan Kristian; Raoult, Didier; Vitale, Giustina; Olano, Juan P; Ueland, Thor; Aukrust, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    The pathophysiological hallmark of spotted fever group rickettsioses comprises vascular inflammation. Based on the emerging importance of the wingless (Wnt) pathways in inflammation and vascular biology, we hypothesized ...
  • Salvatore, Stefania; Domanska, Diana Ewa; Wood, Mollie; Nordeng, Hedvig Marie Egeland; Sandve, Geir Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Studies on medication safety in pregnancy often rely on an oversimplification of medication use into exposed or non-exposed, without considering intensity and timing of use in pregnancy, or concomitant medication ...