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Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study 
Dumeaux, Vanessa; Børresen-Dale, Anne-Lise; Frantzen, Jan-Ole; Kumle, Merethe; Kristensen, Vessela N; Lund, Eiliv (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)
Introduction The introduction of high-throughput technologies, also called -omics technologies, into epidemiology has raised the need for high-quality observational studies to reduce several sources of ...
Correction: Discovery and validation of breast cancer subtypes 
Kapp, Amy V; Jeffrey, Stefanie S; Langerød, Anita; Børresen-Dale, Anne-Lise; Han, Wonshik; Noh, Dong-Young; Bukholm, Ida R; Nicolau, Monica; Brown, Patrick O; Tibshirani, Robert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Following the publication of our recent article (Kapp et al., BMC Genomics 2006, 7:231), we (the authors) regrettably found several errors in the published Table 5. This correction article not only describes what makes the ...
Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence 
Edvardsen, Hege; Tefre, Toril; Jansen, Laila; Vu, Phuong; Haffty, Bruce G; Fosså, Sophie D; Kristensen, Vessela N; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background The ATM protein is activated as a result of ionizing radiation, and genetic variants of the ATM gene may therefore affect the level of radiation-induced damage. Individuals heterozygous for ATM ...
Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas 
Chanock, Stephen J; Burdett, Laurie; Yeager, Meredith; Llaca, Victor; Langerød, Anita; Presswalla, Shafaq; Kaaresen, Rolf; Strausberg, Robert L; Gerhard, Daniela S; Kristensen, Vessela; Perou, Charles M; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Introduction Genomic alterations have been observed in breast carcinomas that affect the capacity of cells to regulate proliferation, signaling, and metastasis. Re-sequence studies have investigated candidate ...
TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer 
Langerød, Anita; Zhao, Hongjuan; Borgan, Ørnulf; Nesland, Jahn M; Bukholm, Ida R; Ikdahl, Tone; Kåresen, Rolf; Børresen-Dale, Anne-Lise; Jeffrey, Stefanie S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Introduction Gene expression profiling of breast carcinomas has increased our understanding of the heterogeneous biology of this disease and promises to impact clinical care. The aim of this study was to ...
Discovery and validation of breast cancer subtypes 
Kapp, Amy V; Jeffrey, Stefanie S; Langerød, Anita; Børresen-Dale, Anne-Lise; Han, Wonshik; Noh, Dong-Young; Bukholm, Ida R; Nicolau, Monica; Brown, Patrick O; Tibshirani, Robert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background Previous studies demonstrated breast cancer tumor tissue samples could be classified into different subtypes based upon DNA microarray profiles. The most recent study presented evidence for the ...
Evaluation of MetriGenix custom 4D™ arrays applied for detection of breast cancer subtypes 
Aamodt Muggerud, Aslaug; Johnsen, Hilde; Barnes, Debra A; Steel, Adam; Eystein Lønning, Per; Naume, Bjørn; Sørlie, Therese; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background Previously, a total of five breast cancer subtypes have been identified based on variation in gene expression patterns. These expression profiles were also shown to be associated with different ...
ATM variants and cancer risk in breast cancer patients from Southern Finland 
Tommiska, Johanna; Jansen, Laila; Kilpivaara, Outi; Edvardsen, Hege; Kristensen, Vessela; Tamminen, Anitta; Aittomäki, Kristiina; Blomqvist, Carl; Børresen-Dale, Anne-Lise; Nevanlinna, Heli (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background Individuals heterozygous for germline ATM mutations have been reported to have an increased risk for breast cancer but the role for ATM genetic variants for breast cancer risk has remained unclear. ...
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms 
Sørlie, Therese; Wang, Yulei; Xiao, Chunlin; Johnsen, Hilde; Naume, Bjørn; Samaha, Raymond R; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background Gene expression profiling has been used to define molecular phenotypes of complex diseases such as breast cancer. The luminal A and basal-like subtypes have been repeatedly identified and validated ...
Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters 
Baumbusch, Lars O; Myhre, Simen; Langerød, Anita; Bergamaschi, Anna; Geisler, Stephanie B; Lønning, Per E; Deppert, Wolfgang; Dornreiter, Irene; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background The tumor suppressor gene p53 (TP53) controls numerous signaling pathways and is frequently mutated in human cancers. Novel p53 isoforms suggest alternative splicing as a regulatory feature of ...
Multilocus analysis of SNP and metabolic data within a given pathway 
Kristensen, Vessela N; Tsalenko, Anya; Geisler, Jurgen; Faldaas, Anne; Grenaker, Grethe I; Lingjærde, Ole C; Fjeldstad, Ståle; Yakhini, Zohar; Lønning, Per E; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges facing ...
Early detection of breast cancer based on gene-expression patterns in peripheral blood cells 
Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Urdal, Petter; Berghagen, Hege; Jensen, Marianne; Kristiansen, Lena; Moen, Cecilie; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Akslen, Lars A; Schlichting, Ellen; Børresen-Dale, Anne-Lise; Lönneborg, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
Introduction Existing methods to detect breast cancer in asymptomatic patients have limitations, and there is a need to develop more accurate and convenient methods. In this study, we investigated whether ...
Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients 
Schaner, Marci E; Davidson, Ben; Skrede, Martina; Reich, Reuven; Flørenes, Vivi A; Risberg, Björn; Berner, Aasmund; Goldberg*, Iris; Givant-Horwitz, Vered; Tropè, Claes G; Kristensen, Gunnar B; Nesland, Jahn M; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
Background While numerous studies have characterized primary ovarian tumors, little information is available regarding expression patterns of metastatic sites of this cancer. To define sets of genes that ...
Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer 
Yoshimura, Noriko; Harada, Nobuhiro; Bukholm, Ida; Kåresen, Rolf; Børresen-Dale, Anne-Lise; Kristensen, Vessela N (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2003)
Introduction The expression of the oestrogen receptor (ER) is one of the more important clinical parameters of breast cancer. However, the relationship between the ER and its ligand, oestradiol, and the ...
Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis 
Zhao, Hongjuan; Hastie, Trevor; Whitfield, Michael L; Børresen-Dale, Anne-Lise; Jeffrey, Stefanie S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2002)
Background T7 based linear amplification of RNA is used to obtain sufficient antisense RNA for microarray expression profiling. We optimized and systematically evaluated the fidelity and reproducibility ...
 
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Date Issued2008 (1)2007 (4)2006 (6)2005 (2)2003 (1)2002 (1)Document TypeTidsskriftartikkel (15)Author
Børresen-Dale, Anne-Lise (15)
Langerød, Anita (5)Jeffrey, Stefanie S (4)Kristensen, Vessela N (4)Bukholm, Ida R (3)... View MorePeer ReviewedPeer reviewed (15)
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