• English
    • Norsk
  • English 
    • English
    • Norsk
  • Administration
Search 
  •   Home
  • Det matematisk-naturvitenskapelige fakultet
  • Farmasøytisk institutt
  • Farmasøytisk institutt
  • Search
  •   Home
  • Det matematisk-naturvitenskapelige fakultet
  • Farmasøytisk institutt
  • Farmasøytisk institutt
  • Search
JavaScript is disabled for your browser. Some features of this site may not work without it.

Search

Show Advanced FiltersHide Advanced Filters

Filters

Use filters to refine the search results.

Now showing items 1-100 of 135

  • Sort Options:
  • Relevance
  • Title Asc
  • Title Desc
  • Issue Date Asc
  • Issue Date Desc
  • Results Per Page:
  • 5
  • 10
  • 20
  • 40
  • 60
  • 80
  • 100
Effects of a human-based mixture of persistent organic pollutants on the in vivo exposed cerebellum and cerebellar neuronal cultures exposed in vitro 
Berntsen, Hanne Friis; Duale, Nur; Bjørklund, Cesilie Granum; Rangel-Huerta, Oscar Daniel; Dyrberg, Kine; Hofer, Tim; Rakkestad, Kirsten Eline; Østby, Gunn Charlotte; Halsne, Ruth; Boge, Gudrun Seeberg; Paulsen, Ragnhild Elisabeth; Myhre, Oddvar; Ropstad, Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Exposure to persistent organic pollutants (POPs), encompassing chlorinated (Cl), brominated (Br) and perfluoroalkyl acid (PFAA) compounds is associated with adverse neurobehaviour in humans and animals, and is observed to ...
Exposure to human relevant mixtures of halogenated persistent organic pollutants (POPs) alters neurodevelopmental processes in human neural stem cells undergoing differentiation 
Davidsen, Nichlas; Lauvås, Anna Jacobsen; Myhre, Oddvar; Ropstad, Erik; Carpi, Donatella; Mendoza-de Gyves, Emilio; Berntsen, Hanne Friis; Dirven, Hubert; Paulsen, Ragnhild Elisabeth; Bal-Price, Anna; Pistollato, Francesca (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Halogenated persistent organic pollutants (POPs) like perfluorinated alkylated substances (PFASs), brominated flame retardants (BFRs), organochlorine pesticides and polychlorinated biphenyls (PCBs) are known to cause cancer, ...
A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: A randomized controlled trial 
Monsen, Ragnhild Elisabeth; Herlofson, Bente Brokstad; Gay, Caryl; Fjeld, Katrine Gahre; Hove, Lene Hystad; Malterud, Karl Egil; Saghaug, Elisabeth; Slaaen, Joran; Sundal, Tone; Tollisen, Anita; Lerdal, Anners (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim: This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to ...
Interactions of natural deep eutectic solvents (NADES) with artificial and natural membranes 
Nystedt, Helene Liepelt; Grønlien, Krister Gjestvang; Tønnesen, Hanne Hjorth (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Natural deep eutectic solvents (NADES) are a third type of liquids, apart from water and lipids. NADES show promise as drug carriers in dermal formulations or formulations for local administration in the oral cavity due ...
Cellular signaling and molecular regulation governing motility, biofilm formation, and virulence in the Bacillus cereus group 
Smith, Veronika (Doctoral thesis / Doktoravhandling, 2021)
The bacterium Bacillus cereus is increasingly recognized as a major source of food-borne disease, as well as other severe infections. Biofilms are a common multicellular mode of growth, where bacteria can be protected ...
Regulation and functional studies of the cysteine protease legumain in bone cell biology 
Bosnjak, Tatjana (Doctoral thesis / Doktoravhandling, 2020)
Legumain is an enzyme present in most cells but its dysregulation is associated with several diseases. During stem cell differentiation, legumain stimulates fat cell and inhibits osteoblast differentiation. This thesis ...
Electromembrane extraction: Enhanced theoretical understanding and new applications 
Restan, Magnus Saed (Doctoral thesis / Doktoravhandling, 2020)
Main research findings In the field of bioanalysis, drug molecules and endogenous compounds can be determined and quantified from biological samples such as blood and urine. However, the complexity of such biological ...
Effekt av fotodynamisk terapi på cysteinproteasen legumain og hemmeren cystatin E/M Restricted Access
Olsen, Kristine Løkke (Master thesis / Masteroppgave, 2020)
Paper-based smart sampling for bottom-up protein analysis 
Skjærvø, Øystein (Doctoral thesis / Doktoravhandling, 2020)
Paper-based sample collection has gained increased attention during the past few decades for its simplicity and applicability to a wide range of matrices and analytes. Particularly for sampling of blood. Compared to ...
Circadisk påvirkning på farmakokinetikken til mykofenolat og mykofenolatglukuronid i nyretransplanterte pasienter Restricted Access
Kveim, Hanne Kamilla (Master thesis / Masteroppgave, 2020)
Bakgrunn: Etter en nyretransplantasjon er immunsupprimerende behandling helt nødvendig, og mykofenolatmofetil (MMF) inngår som en del av behandlingen og doseres morgen og kveld. Mykofenolat (MPA) glukuronideres til ...
Effects of feeding mice with different Plin genotypes a methionine-choline-deficient (MCD) diet - a model of nonalcoholic steatohepatitis (NASH) disease. Restricted Access
Hellstrand, Ana (Master thesis / Masteroppgave, 2020)
Tools to optimize the immunosuppressive treatment after renal transplantation 
Gustavsen, Marte Theie (Doctoral thesis / Doktoravhandling, 2020)
Livelong immunosuppressive treatment is needed after renal transplantation. Tacrolimus has been the cornerstone in most transplant centers. Its narrow therapeutic window and large inter- and intra-individual variability ...
Lactate receptor HCAR1 in the protection against neuroinflammation in stroke 
Brox, Camilla (Master thesis / Masteroppgave, 2020)
Isolation of bacterial vesicles and characterisation of their genetic cargo 
Langlete, Petter (Doctoral thesis / Doktoravhandling, 2020)
Extracellular vesicles are small round bodies secreted from the membranes of most living cells, including bacteria. The bacterial vesicles contain many of the same components as the mother bacteria and play numerous roles ...
Strekkodeassistert legemiddeladministrering i sykehus – en observasjonsstudie 
Nielsen, Synne Margrethe (Master thesis / Masteroppgave, 2020)
The effect of a pharmacist consultation on pregnant women’s quality of life with a special focus on nausea and vomiting: an intervention study 
Truong, Maria B; Ngo, Elin; Ariansen, Hilde; Tsuyuki, Ross T; Nordeng, Hedvig (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Maternal wellbeing and quality of life (QOL) are increasingly being recognized as important for healthy pregnancies. The aim of this study was to investigate the impact of a pharmacist consultation ...
Medication-related problems among hospitalized pregnant women in a tertiary teaching hospital in Ethiopia: a prospective observational study 
Ahmed, Seid M; Sundby, Johanne; Aragaw, Yesuf A; Nordeng, Hedvig (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Studies on medication-related problems (MRPs) among pregnant women are scarce, despite the potential consequences for both mother and child. This study aimed to describe the prevalence, clinical significance, ...
Immunomodulating polysaccharides, triterpenoids and melanin from the medicinal fungus Inonotus obliquus (Chaga) 
Wold, Christian Winther (Doctoral thesis / Doktoravhandling, 2020)
Inonotus obliquus (Chaga) is a strange-looking fungus growing on birch trees in the Northern Hemisphere. Chaga is perhaps best known for its use in traditional medicine, where the fungus is used as an herbal tea against ...
New concepts for personalized immunosuppression in the transplanted patient 
Klaasen, Rolf Anton (Doctoral thesis / Doktoravhandling, 2020)
After transplantation patients receive individualized immunosuppressive treatment based on drug concentrations to hinder rejection of the transplant. This thesis aimed to develop and apply alternative methods of measuring ...
How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa) 
Cheesman, Rosa; Eilertsen, Espen M; Ahmadzadeh, Yasmin I; Gjerde, Line C; Hannigan, Laurie J; Havdahl, Alexandra; Young, Alexander I; Eley, Thalia C; Njølstad, Pål R; Magnus, Per; Andreassen, Ole A; Ystrom, Eivind; McAdams, Tom A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Many studies detect associations between parent behaviour and child symptoms of anxiety and depression. Despite knowledge that anxiety and depression are influenced by a complex interplay of genetic and environmental ...
Effekter av SERCA-aktivator CDN1163 på regulering av energimetabolismen i humane skjelettmuskelceller 
Ghobadi, Roya (Master thesis, Group thesis / Masteroppgave, Gruppeoppgave, 2020)
Elektromembranekstraksjon av THC-syre 
Vo, Kimmi Thoa (Master thesis / Masteroppgave, 2020)
Elektromembranekstraksjon (EME) har siden den første publiserte artikkelen i 2006, vist seg å være en effektiv prøveopparbeidelsesmetode til ekstraksjon av blant annet sure og basiske legemidler, hvor det foreligger flest ...
Liposomer med nøytrale polymerer i utvikling av legemidler mot tørr munn 
Andresen, Patrick (Master thesis / Masteroppgave, 2020)
Hensikt: Fremstille bioadhesive liposomer med innkapslet glyserol for fukting av slimhinnene i munnhulen. Metode: Liposomer med ulike lipidsammensetninger ble tillaget ved to like metoder og med to nøytrale polymerer hvor ...
Identifying targets for antibiotic stewardship interventions through analysis of the antibiotic prescribing process in hospitals - a multicentre observational cohort study 
Wathne, Jannicke S; Skodvin, Brita; Charani, Esmita; Harthug, Stig; Blix, Hege S; Nilsen, Roy M; Kleppe, Lars K S; Vukovic, Marta; Smith, Ingrid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for antibiotic stewardship interventions in ...
Dendritic localization and exocytosis of NAAG in the rat hippocampus 
Nordengen, Kaja; Morland, C; Slusher, B.S.; Gundersen, V (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
While a lot is known about classical, anterograde neurotransmission, less is known about the mechanisms and molecules involved in retrograde neurotransmission. Our hypothesis is that N-acetylaspartylglutamate (NAAG), the ...
Extending balance assessment for the generalized propensity score under multiple imputation 
Frank, Anna-Simone; Matteson, David S.; Solvang, Hiroko Kato; Lupattelli, Angela; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
This manuscript extends the definition of the Absolute Standardized Mean Difference (ASMD) for binary exposure (M = 2) to cases for M > 2 on multiple imputed data sets. The Maximal Maximized Standardized Difference (MMSD) ...
Miniatyrisering av terapeutisk legemiddelmonitorering av psykofarmaka basert på Volumetric Absorptive Microsampling og Parallell artifical liquid membrane extraction 
Truong, Hoai Thi My (Master thesis / Masteroppgave, 2020)
Psykofarmaka omfatter antipsykotika, antidepressiva, anxiolytika (angstdempende legemidler), sedativa (beroligende legemidler) og hypnotika (sovemidler). Det er vanskelig å vurdere effekt av psykofarmaka, og behandlingen ...
Pediatrisk dosetilpasning av prednisolon – manipulering av tablett eller apotekfremstilt mikstur? Restricted Access
Svendsen, Randi Maria Hamre (Master thesis / Masteroppgave, 2020)
Rheumatoid Arthritis Patients, Both Newly Diagnosed and Methotrexate Treated, Show More DNA Methylation Differences in CD4+ Memory Than in CD4+ Naïve T Cells 
Guderud, Kari; Sunde, Line Hagen; Flåm, Siri Tennebø; Mæhlen, Marthe Thoresen; Mjaavatten, Maria Dahl; Lillegraven, Siri; Aga, Anna-Birgitte; Evenrød, Ida Marie; Norli, Ellen Sauar; Andreassen, Bettina Kulle; Franzenburg, Sören; Franke, Andre; Haavardsholm, Espen Andre; Rayner, Simon; Gervin, Kristina; Lie, Benedicte Alexandra (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background: Differences in DNA methylation have been reported in B and T lymphocyte populations, including CD4+ T cells, isolated from rheumatoid arthritis (RA) patients when compared to healthy controls. CD4+ T cells are ...
Apotekets intervensjoner under reseptekspedisjonen Restricted Access
Sparby, Karoline (Master thesis / Masteroppgave, 2020)
Bakgrunn: Apotekfarmasøytene bidrar til riktig legemiddelbruk i befolkningen og er siste skanse før pasienten mottar legemidlene sine. Før utlevering av legemidlene utføres farmasøytkontroll der det kan avdekkes feil eller ...
Medication use challenges among immigrants originating from Syria living in Norway - with focus on antibiotics Restricted Access
Deeb, George (Master thesis / Masteroppgave, 2020)
Antibiotikabruk hos barn og nyfødte innlagt ved Akershus Universitetssykehus Restricted Access
Ahmed, Sanya (Master thesis / Masteroppgave, 2020)
Bakgrunn: Økende antibiotikaresistens er i dag en velkjent utfordring og en alvorlig trussel for global helse. Forekomsten av antibiotikaresistens er foreløpig relativt lavt i Norge, men for å unngå økning har de norske ...
Management of Type 2 Diabetes in Non-Western Patient Groups: Results from Pakistani and Kurdish immigrant populations in Norway and from the native population in the United Arab Emirates 
Abuelmagd, Walaa (Doctoral thesis / Doktoravhandling, 2020)
In this thesis, it has been shown that the management of Type 2 diabetes mellitus (T2DM) in the immigrant women in Norway and the native Emirati women in the United Arab Emirates was largely suboptimal in terms of lifestyle ...
Diagnostic tests and treatment procedures performed prior to cardiovascular death in individuals with severe mental illness 
Heiberg, Ina Heidi; Nesvåg, Ragnar; Balteskard, Lise; Bramness, Jørgen Gustav; Hultman, Christina M.; Næss, Øyvind; Reichborn-Kjennerud, Ted; Ystrøm, Eivind; Jacobsen, Bjarne K.; Høye, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Objective To examine whether severe mental illnesses (i.e., schizophrenia or bipolar disorder) affected diagnostic testing and treatment for cardiovascular diseases in primary and specialized health care. Methods We ...
Reuse of Magnetic Molecularly Imprinted Polymers An Evaluation of Polymers Targeting the Signature Peptide of ProGastrin Releasing Peptide 
Petrovic, Jasna (Master thesis / Masteroppgave, 2020)
Molecularly Imprinted Polymers (MIPs) are tailor-made polymers with high affinity for a specific target. They can be used for selective sample preparation prior to liquid chromatography mass spectrometry determination of ...
Akutte effekter av kuldeeksponering på smertemodulering Restricted Access
Velle, Therese (Master thesis / Masteroppgave, 2020)
Bacterial protein systems at the membrane interface: Structural and biophysical studies of the E.coli adhesion receptor intimin and the magnesium transporter MgtA 
Weikum, Julia Anna (Doctoral thesis / Doktoravhandling, 2020)
Pathogenic Escherichia coli, such as EPEC and EHEC, remain a global threat, responsible for millions of acute diseases worldwide. The dissertation by Julia Weikum investigates two E. coli proteins, which are involved with ...
Impact of the deletion of syntrophins and AQP4 on the prevalence of astrocytic gap junctions Restricted Access
Jovanovic, Nenad (Master thesis / Masteroppgave, 2020)
Forlikelighet av TPN og legemidler som parallellinfusjon til nyfødte Restricted Access
Vidas, Liv (Master thesis / Masteroppgave, 2020)
Kritisk syke nyfødte og prematurt fødte spedbarn innlagt på nyfødtintensivavdeling trenger ofte kontinuerlig tilførsel av total parenteral næring (TPN) og mange legemidler. De fleste legemidlene må gis intravenøst, og på ...
Sleep problems and depressive symptoms in toddlers and 8-year-old children: A longitudinal study 
Sivertsen, Børge; Harvey, Allison G.; Reichborn-Kjennerud, Ted; Ystrøm, Eivind; Hysing, Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Sleep and depression are interlinked throughout the lifespan, but very few studies have examined the directionality of the sleep–depression link in children. The aim of the current study was to prospectively examine the ...
Betydningen av kombinasjonsbruk med valproat for metabolismen av klozapin in vivo Restricted Access
Tran, Thu Thuy Anh (Master thesis / Masteroppgave, 2020)
Bakgrunn: Klozapin er det mest effektive legemiddelet for behandling av schizofreni, men er samtidig assosiert med alvorlig bivirkningsrisiko. Hos pasienter med bipolare tilleggssymptomer, såkalt schizoaffektiv lidelse, ...
Effekter av kuldeeksponering på smerte 
Boutakhrit, Amal (Master thesis / Masteroppgave, 2020)
3D printing of pharmaceuticals: From printed product variability study to direct powder 3D printing Restricted Access
Hosseini, Navid (Master thesis / Masteroppgave, 2020)
This study aims to investigate the variation of the 3D printers Ultimaker 3 and ZMorph VX by printing 80 cylindrical products from the same model on different positions on the build plate and comparing the diameter, height ...
Synthetic Studies Towards Benzo-RvD1n-3 DPA 
Lerstad, Nora Dotterud (Master thesis / Masteroppgave, 2020)
The focus of this thesis has been to develop a total synthesis of benzo-RvD1n-3 DPA, which is an analog of the specialized pro-resolving lipid mediator (SPM) named RvD1n-3 DPA. The synthetic methods towards the α-fragment ...
Optimization of electromembrane extraction with a prototype commercial device 
Drobnjak, Milena (Master thesis / Masteroppgave, 2020)
Electromembrane extraction (EME) is a principle for sample preparation, evolved from the principle of liquid-liquid extraction. In EME an electrical field facilitates the extraction of target analytes from an aqueous sample, ...
Tilpassing av legemiddelkommunikasjon på sykehuset til pasientens helsekompetanse 
Bengtsson, Kajsa Rebecka (Master thesis / Masteroppgave, 2020)
Innledning: Helsekompetanse beskriver personers evne til å ta kunnskapsbaserte beslutninger om egen helse. Når pasienter skrives ut fra sykehus pålegges de et ansvar å mestre egen sykdom og legemiddelinformasjonen må derfor ...
Studier av teriparatid på differensiering av stamceller til osteoblaster og regulering av cysteinproteasene legumain og cathepsin B Restricted Access
Ciyow, Nasra Yusuf (Master thesis / Masteroppgave, 2020)
Osteoporose er en sykdom i skjelettet hvor nedbrytningen av bein går raskere enn nydannelsen. De viktigste cellene som inngår i beinhomeostasen er osteoklaster som bryter ned bein og osteoblaster som bygger opp bein. ...
The lactate receptor HCAR1 in the regulation of neurogenesis and angiogenesis during stroke Restricted Access
Phan, Kimberly Dungdung (Master thesis / Masteroppgave, 2020)
Millions of people suffer from stroke every year, being a leading cause of morbidity and mortality worldwide. The current pharmacological and endovascular therapies in stroke aim to restore cerebral blood flow, but are not ...
Comparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes 
Seljetun, Kristin Opdal; Sandvik, Morten; Vindenes, Vigdis; Eliassen, Elin; Øiestad, Elisabeth Leere; Madslien, Knut Ivar Engesæter; Moe, Lars (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Exposure of wildlife and domestic animals to anticoagulant rodenticides (ARs) is a worldwide concern, but few methods exist to determine residue levels in live animals. Traditional liver detection methods preclude determining ...
Betyding av polymorfismer i kandidatgen for variasjon i serumkonsentrasjon av klozapin 
Mæland, Sondre (Master thesis / Masteroppgave, 2020)
Effects of different antibiotic treatment lengths on gut microbiota and development of resistance : a PCR and qPCR approach 
Ek, Ahmed Nahil Yasen (Master thesis / Masteroppgave, 2020)
Thyroid hormone replacement therapy patterns in pregnant women and perinatal outcomes in the offspring 
Frank, Anna-Simone; Lupattelli, Angela; Matteson, David S.; Meltzer, Helle Margrete; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Purpose It remains unknown to what degree thyroid hormone replacement therapy (THRT) during and initiation after pregnancy determines pregnancy outcomes. The present study primarily aimed to quantify the impact of THRT ...
Treatment of human skeletal muscle cells with inhibitors of diacylglycerol acyltransferases 1 and 2 to explore isozyme-specific roles on lipid metabolism. 
Thoresen, Hege; Kase, Eili Tranheim; Skagen, Christine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Diacylglycerol acyltransferases (DGAT) 1 and 2 catalyse the final step in triacylglycerol (TAG) synthesis, the esterification of fatty acyl-CoA to diacylglycerol. Despite catalysing the same reaction and being present in ...
Effekter av kuldeeksponering på nevropsykologisk funksjon 
Rafiq, Sana (Master thesis / Masteroppgave, 2020)
Legumain in Acute Coronary Syndromes: A Substudy of the PLATO (Platelet Inhibition and Patient Outcomes) Trial 
Gregersen, Ida; Michelsen, Annika; Lunde, Ngoc Nguyen; Åkerblom, Axel; Lakic, Tatevik G.; Skjelland, Mona; Skagen, Karolina Ryeng; Becker, Richard C.; Lindbäck, Johan; Himmelmann, Anders; Solberg, Rigmor; Johansen, Harald Thidemann; James, Stefan K.; Siegbahn, Agneta; Storey, Robert F.; Kontny, Frederic; Aukrust, Pål; Ueland, Thor; Wallentin, Lars; Halvorsen, Bente (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background The cysteine protease legumain is increased in patients with atherosclerosis, but its causal role in atherogenesis and cardiovascular disease is still unclear. The aim of the study was to investigate the ...
Plantebaserte legemidler og doping: En litteraturundersøkelse om plantebaserte legemidler kan inneholde forbudte stoffer i idretten Restricted Access
Puventhiran, Nithuja (Master thesis / Masteroppgave, 2020)
Sammendrag Bakgrunn: Hovedhensikten med denne studien var å utføre en litteraturstudie for å undersøke om plantene fra de plantebaserte legemidlene som er markedsført i Norge har kjent innhold av stoffer som står på ...
Association of coincident self-reported mental health problems and alcohol intake with all-cause and cardiovascular disease mortality: A Norwegian pooled population analysis 
Degerud, Eirik Magnus Meek; Høiseth, Gudrun; Mørland, Jørg Gustav; Ariansen, Inger; Graff-Iversen, Sidsel; Ystrøm, Eivind; Zuccolo, Luisa; Næss, Øyvind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background The disease burden attributable to mental health problems and to excess or harmful alcohol use is considerable. Despite a strong relationship between these 2 important factors in population health, there are ...
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice 
Kvello, Anne Marte Sjursen; Andersen, Jannike Mørch; Boix, Fernando; Mørland, Jørg; Bogen, Inger Lise (Journal article / Tidsskriftartikkel / SubmittedVersion, 2020)
We have previously demonstrated that heroin's first metabolite, 6‐acetylmorphine (6‐AM), is an important mediator of heroin's acute effects. However, the significance of 6‐AM to the rewarding properties of heroin still ...
Polyfenoler i Hypericum maculatum og Hypericum perforatum. Isolasjon, antioksidant og lipoksygenasehemmende effekter. Oversikt over polyfenolenes effekter på mekanismer assosiert med Alzheimers sykdom Restricted Access
Jensen, Mari-Ann Håkonsrud (Master thesis / Masteroppgave, 2020)
Motilitetsrepressoren MogR i Bacillus cereus-gruppen – Ekspresjonsanalyser og kloning av mogR-FLAG for global kartlegging av DNA-bindingsseter Restricted Access
Samari, Kouros Andre (Master thesis / Masteroppgave, 2020)
Medlemmer av Bacillus cereus-gruppen (B. cereus sensu lato) er Gram-positive, stavformede, aerobe eller fakultativt anaerobe, sporedannende bakterier med en vid utbredelse i det naturlige miljøet. Alle etablerte arter i ...
Prenatal exposure to methadone or buprenorphine alters µ-opioid receptor binding and downstream signaling in the rat brain 
Kongstorp, Mette; Bogen, Inger Lise; Steinsland, Synne; Nerem, Elisabeth; Salih, Triske Woshyar; Stiris, Tom; Andersen, Jannike Mørch (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
There is a growing concern related to the use of opioid maintenance treatment during pregnancy. Studies in both humans and animals have reported reduced cognitive functioning in offspring prenatally exposed to methadone ...
The cure model in perinatal epidemiology 
Stoltenberg, Emil Aas; Nordeng, Hedvig Marie Egeland; Ystrøm, Eivind; Samuelsen, Sven Ove (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
In the statistical literature, the class of survival analysis models known as cure models has received much attention in recent years. Cure models seem not, however, to be part of the statistical toolbox of perinatal ...
Effekten av høy-dose omega-3-fettsyrer på farmakokinetikken til takrolimus og mykofenolat i nyretransplanterte pasienter Restricted Access
Gence, Berfin (Master thesis / Masteroppgave, 2020)
Measured GFR by Utilizing Population Pharmacokinetic Methods to Determine Iohexol Clearance 
Åsberg, Anders; Bjerre, Anna Kristina; Almaas, Runar; Luis-Lima, Sergio; Robertsen, Ida; Salvador, Cathrin Lytomt; Porrini, Esteban; Schwartz, George; Hartmann, Anders; Bergan, Stein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Introduction There is an increasing demand for accurately measured glomerular filtration rate (GFR). Iohexol serum clearance has become a new gold standard, but it is challenging when GFR is low and 24-hour sampling is ...
Phenotypic Characterization of Larval Zebrafish (Danio rerio) with Partial Knockdown of the cacna1a Gene 
Gawel, Kinga Aurelia; Turski, Waldemar A.; van der Ent, Wietske; Mathai, Benan John; Kirstein-Smardzewska, Karolina Joanna; Simonsen, Anne; Esguerra, Camila V. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The CACNA1A gene encodes the pore-forming α1 subunit of voltage-gated P/Q type Ca2+ channels (Cav2.1). Mutations in this gene, among others, have been described in patients and rodents suffering from absence seizures and ...
Preterm birth and risk for language delays before school entry: A sibling-control study 
Zambrana, Imac Maria; Vollrath, Margarete Erika Maria Torgerse; Jacobsson, Bo; Sengpiel, Verena; Ystrøm, Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
We investigated whether children born preterm are at risk for language delay using a sibling-control design in the Norwegian Mother and Child Cohort Study (MoBa), conducted by the Norwegian Institute of Public Health. ...
ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo 
Samuelsen, Ørjan; Åstrand, Ove Alexander Høgmoen; Frøhlich, Christopher; Heikal, Adam; Skagseth, Susann; Carlsen, Trine Josefine Olsen; Leiros, Hanna-Kirsti S.; Bayer, Annette; Schnaars, Christian; Kildahl-andersen, Geir; Lauksund, Silje; Finke, Sarah; Huber, Sandra; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Økstad, Ole Andreas; Rongved, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Carbapenem-resistant Gram-negative pathogens are a critical public health threat and there is an urgent need for new treatments. Carbapenemases (β-lactamases able to inactivate carbapenems) have been identified in both ...
Synthesis and Biological Evaluation of Analogs of Didehydroepiandrosterone as Potential New Anticancer Agents 
J Solum, Eirik; Liekens, Sandra; Hansen, Trond Vidar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The synthesis, cytotoxicity and inhibition of CDK8 by thirteen analogs of cortistatin A are reported. These efforts revealed that the analogs with either a 6- or 7-isoquinoline or 5-indole side chain in the 17-position are ...
Comparing Two Methods of Tablet Manipulation to Adjust the Warfarin Dose in Paediatric Care 
Brustugun, Jørgen; Aas, Elisabeth Birkedal; Tho, Ingunn; Bjerknes, Kathrin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Tablets containing prescribed doses are not always available, and this is of particular importance in paediatric care where suitable age-appropriate formulations are generally lacking. To obtain a child-adjusted dose, ...
Effekter av β2-adrenerge agonister på glukoseopptak og proteinsyntese i dyrkede humane skjelettmuskeceller 
Ehsani, Mehrdad (Master thesis / Masteroppgave, 2020)
Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages 
Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi; Michelsen, Annika; Otterdal, Kari; Yndestad, Arne; Broch, Kaspar; Gullestad, Lars; Nyman, Tuula Anneli; Bendz, Bjørn; Eritsland, Jan; Hoffmann, Pavel; Skagen, Karolina Ryeng; Gonçalves, Isabel; Nilsson, Jan; Grenegård, Magnus; Poreba, Marcin; Drag, Marcin; Seljeflot, Ingebjørg; Sporsheim, Bjørnar; Espevik, Terje; Skjelland, Mona; Johansen, Harald Thidemann; Solberg, Rigmor; Aukrust, Pål; Björbacka, Harry; Andersen, Geir Øystein; Halvorsen, Bente (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background and aims We have previously found increased levels of the cysteine protease legumain in plasma and plaques from patients with carotid atherosclerosis. This study further investigated legumain during acute ...
Mechanisms linking parental educational attainment with child ADHD, depression, and academic problems: a study of extended families in The Norwegian Mother, Father and Child Cohort Study 
Torvik, Fartein Ask; Eilertsen, Espen Moen; McAdams, Tom A.; Gustavson, Kristin; Zachrisson, Henrik Daae; Brandlistuen, Ragnhild Eek; Gjerde, Line C.; Havdahl, Alexandra; Stoltenberg, Camilla; Ask, Helga; Ystrøm, Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Low educational attainment in parents is associated with child psychopathology. It is not clear whether the associations are due to risk factors that family members share or due to effects of maternal or ...
Fordeling av og nevronal utvikling etter opioider administrert i kyllingembryo Studier utført in vivo og i nevronkulturer 
Khoder, Ala Zaim (Master thesis / Masteroppgave, 2020)
Legemiddelkommunikasjon mellom helsepersonell og pasient på sykehus og betydningen for etterlevelse etter utskriving - en kvalitativ studie 
Lie, Helene Berg (Master thesis / Masteroppgave, 2020)
Innledning: Studier har vist at bare 50 prosent av kronisk syke pasienter etterlever legemiddelbehandlingen. I følge WHO sin modell for etterlevelse påvirkes etterlevelse av fem faktorer: pasientrelaterte, sosioøkonomiske, ...
Paracetamol og mulige nevrotoksiske effekter - in vitro studier i kyllingkornceller og optimalisering av studier i humane cellelinjemodeller; SH-SY5Y og NTERA2 Restricted Access
Houdaifi, Nora (Master thesis / Masteroppgave, 2020)
Paracetamol er førstevalget ved behov for smertestillende og/eller febernedsettende effekt hos gravide. Legemiddelet har vært brukt i 70 år og har vært ansett som trygt å bruke under svangerskap. Nyere epidemiologiske ...
Pharmacological Validation of the Prepulse Inhibition of Startle Response in Larval Zebrafish using a Commercial Automated System and Software 
Banono, Nancy Saana; Esguerra, Camila (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
While there is an abundance of commercial and standardized automated systems and software for performing the prepulse inhibition (PPI) assay in rodents, to the best of our knowledge, all PPI assays performed in the zebrafish ...
Y-site physical compatibility of Numeta G13E with drugs frequently used at Neonatal Intensive Care 
Nezvalova-henriksen, Katerina; Østerberg, Camilla Tomine; Nilsson, Niklas; Staven Berge, Vigdis; Tho, Ingunn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Preterm neonates require parenteral nutrition (PN) in addition to intravenous drug therapy. Due to limited venous access, drugs are often co-administered with PN via the same lumen. If incompatible, precipitation and ...
The PPAR Ω Pocket: Renewed Opportunities for Drug Development 
Kaupang, Åsmund; Hansen, Trond Vidar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The past decade of PPARγ research has dramatically improved our understanding of the structural and mechanistic bases for the diverging physiological effects of different classes of PPARγ ligands. The discoveries that lie ...
Non-prescription purchase of antibiotics during travel abroad among a general adult population in Norway: Findings from the seventh Tromsø Study 
Gravningen, Kirsten Midttun; Field, Nigel; Blix, Hege Salvesen; Asfeldt, anne mette; Småbrekke, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Non-prescription purchase of antibiotics is undesirable and has not recently been investigated in a representative population in a high-income low-use country during travel abroad. This study examined ...
New CDK8 inhibitors as potential anti-leukemic agents – Design, synthesisand biological evaluation 
Solum, Eirik Johansson; Hansen, Trond Vidar; Aesoy, Reidun; Herfindal, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Cyclin-dependent kinase 8 (CDK8) plays a vital role in regulating cell transcription either through its association with the mediator complex or by the phosphorylation of transcription factors. CDK8-mediated activation of ...
Antibiotikabruk hos pasienter som legges inn på sykehus med samfunnservervet pneumoni og KOLS-eksaserbasjon Restricted Access
Flatebø, Trude Eline (Master thesis / Masteroppgave, 2020)
The Impact of ion balance in electromembrane extraction 
Jaghl, Mohamad Fadi Mohamad (Master thesis / Masteroppgave, 2020)
Antibiotikabruk ved samfunnservervet pneumoni og KOLS eksaserbasjon Effekt av en sammensatt intervensjon på etterlevelse av nasjonal faglig retningslinje og forskrivningspraksis Restricted Access
Seljeflot, Liv Marit (Master thesis / Masteroppgave, 2020)
Hensikt Hensikten med denne studien var å kartlegge antibiotikabruk hos pasienter i sykehus med samfunnservervet pneumoni eller KOLS eksaserbasjon, samt å undersøke hvorvidt gjeldende retningslinje for behandling følges. ...
Kan legemiddelgjennomgang i sykehus forbedre legemiddelbehandlingen i kommunehelsetjenesten? En prospektiv undersøkelse i seks kommuner på Vestlandet 
Nyhammer-Taklo, Randi Elisabeth (Master thesis / Masteroppgave, 2020)
Hensikt: Hensikten med denne studien var å kartlegge oppfølgingen av anbefalte legemiddelintervensjoner etter legemiddelgjennomgang i sykehus når pasienten var tilbake i kommunehelsetjenesten, herunder hvilke legemiddelrelaterte ...
Studie av hvordan barn aksepterer medisiner Restricted Access
Ivanovic, Ivana (Master thesis / Masteroppgave, 2020)
Phytochemical analysis of Tragopogon floccosus (Compositae) Restricted Access
Nguyen, Teresa Thanh Truc Huynh (Master thesis / Masteroppgave, 2020)
Determination of anticoagulant rodenticides in faeces of exposed dogs and in a healthy dog population 
Seljetun, Kristin O; Vindenes, Vigdis; Øiestad, Elisabeth L; Brochmann, Gerd-Wenche; Eliassen, Elin; Moe, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Exposure to anticoagulant rodenticides (ARs) in dogs is among the most common causes of poisoning in small animal practice, but information about toxicokinetic of these rodenticides in dogs is lacking. We ...
Potentially inappropriate prescribing to older patients receiving multidose drug dispensing 
Josendal, Anette V; Bergmo, Trine S; Granas, Anne G (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Multidose drug dispensing (MDD) is an adherence aid that provides patients with machine-dispensed medicines in disposable unit bags, usually for a 14 day period. Previous studies have suggested that the quality ...
Effekten av SENP2 på glukose- og oljesyremetabolismen i humane myotuber Restricted Access
Sistek, Medina (Master thesis / Masteroppgave, 2020)
Bakgrunn: Overvekt, fedme og diabetes mellitus type 2 er et voksende problem i det globale perspektiv. Økt fettvevsmasse er sterkt assosiert med utvikling av insulinresistens og diabetes mellitus type 2. I mus er ...
Fertility treatment and oral contraceptive discontinuation for identification of pregnancy planning in routinely collected health data – an application to analgesic and antibiotic utilisation 
Hjorth, Sarah; Wood, Mollie; Tauqeer, Fatima; Nordeng, Hedvig (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Women with unplanned pregnancies use folic acid less frequently, and more often use potentially teratogenic medications in the first trimester. Yet most studies based on routinely collected data lack information ...
Prenatal eksponering for metadon eller buprenorfin og tilbøyelighet for senere rusbruk - Kinetikk- og atferdsstudier i mus 
Kumarasamy, Sandra Trones (Master thesis / Masteroppgave, 2020)
Gravide kvinner i legemiddelassistert rehabilitering (LAR) anbefales å opprettholde behandlingen i svangerskapet på tross av manglende kunnskap om mulige negative korttids- og langtidseffekter i deres fostre og barn. En ...
A natural deep eutectic solvent (NADES) as potential excipient in collagen-based products 
Grønlien, Krister Gjestvang; Pedersen, Mona Elisabeth; Tønnesen, Hanne Hjorth (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Natural deep eutectic solvents (NADES) have previously shown antibacterial properties alone or in combination with photosensitizers and light. In this study, we investigated the behavior of the structural protein collagen ...
Correlation of body weight and composition with hepatic activities of cytochrome P450 enzymes 
Krogstad, Veronica; Peric, Alexandra; Robertsen, Ida; Kringen, Marianne K.; Vistnes, Maria; Hjelmesæth, Jøran; Sandbu, Rune; Johnson, Line Kristin; Angeles, Philip Carlo Soriano; Jansson-Löfmark, Rasmus; Karlsson, Cecilia; Andersson, Shalini; Åsberg, Anders; Andersson, Tommy B.; Christensen, Hege Staaland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Obesity is associated with comorbidities of which pharmacological treatment is needed. Physiological changes associated with obesity may influence the pharmacokinetics of drugs, but the effect of body weight on drug ...
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients—a genome-wide association study adjusting for smoking habits 
Smith, Robert Løvsletten; O’Connell, Kevin; Athanasiu, Lavinia; Djurovic, Srdjan; Kringen, Marianne K.; Andreassen, Ole Andreas; Molden, Espen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study ...
Use of Antidepressants in Older People during a 10-Year Period: An Observational Study on Prescribed Doses and Serum Levels 
Tveit, Kristine; Hermann, Monica; Waade, Ragnhild Birkeland; Nilsen, Roy Miodini; Wallerstedt, Susanna M.; Molden, Espen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background According to previous studies, older patients frequently have serum concentrations of antidepressant medication above the recommended reference range. Objective The aim of this study was to investigate ...
Impact of mucin on drug diffusion: Development of a straightforward in vitro method for the determination of drug diffusivity in the presence of mucin 
Falavigna, Margherita; Stein, Paul C.; Flaten, Gøril Eide; Di Cagno, Massimiliano Pio (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Mucosal drug delivery accounts for various administration routes (i.e., oral, vaginal, ocular, pulmonary, etc.) and offers a vast surface for the permeation of drugs. However, the mucus layer which shields and lubricates ...
Maternal characteristics and use of medications in pregnant women that sought medical help due to infertility – a European, cross-sectional web-based study Restricted Access
Ilic, Miljana (Master thesis / Masteroppgave, 2020)
The lactate receptor HCAR1 at the brain-cerebrospinal fluid interface and its role in stroke Restricted Access
Nguyen, Teresa Dang (Master thesis / Masteroppgave, 2020)
Solid lipid nanoparticle-loaded mucoadhesive buccal films – Critical quality attributes and in vitro safety & efficacy 
Tzanova, Martina; Hagesaether, Ellen; Tho, Ingunn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The objective of this work was to develop and characterize solid lipid nanoparticle (SLN)-loaded mucoadhesive films to reveal their potential as successful drug formulations. SLNs based on lipid (Lipoid S100) and surfactant ...
Substrate oxidation in primary human skeletal muscle cells is influenced by donor age 
Aas, Vigdis; Thoresen, G. Hege; Rustan, Arild; Lund, Jenny (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Primary human myotubes represent an alternative system to intact skeletal muscle for the study of human diseases related to changes in muscle energy metabolism. This work aimed to study if fatty acid and glucose ...
  • «
  • 1
  • 2
  • »
 
Responsible for this website 
University of Oslo Library


Contact Us 
duo-hjelp@ub.uio.no


Privacy policy
 

 

For students / employeesSubmit master thesisAccess to restricted material

Browse

All of DUOCommunities & CollectionsBy Issue DateAuthorsTitlesThis CollectionBy Issue DateAuthorsTitles

For library staff

Login

Discover

Date Issued2021 (5)2020 (130)Document TypeTidsskriftartikkel (68)Masteroppgave (56)Doktoravhandling (11)Gruppeoppgave (1)AuthorMolden, Espen (7)Ystrøm, Eivind (6)Paulsen, Ragnhild Elisabeth (5)Berntsen, Hanne Friis (4)Hansen, Trond Vidar (4)... View MorePeer ReviewedPeer reviewed (67)
RSS Feeds
feedRSS 2.0
 
Responsible for this website 
University of Oslo Library


Contact Us 
duo-hjelp@ub.uio.no


Privacy policy