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Now showing items 1-10 of 13
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
We hypothesised that skeletal muscles of healthy young people have a large variation in oxidative capacity and fibre-type composition, and aimed therefore to investigate glucose metabolism in biopsies and myotubes isolated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Ablation of glycosylated lysosomal membrane protein (GLMP, formerly known as NCU-G1) has been shown to cause chronic liver injury which progresses into liver fibrosis in mice. Both lysosomal dysfunction and chronic liver ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
About 80% of patients with type 2 diabetes are classified as overweight. However, only about 1/3 of severely obese subjects have type 2 diabetes. This indicates that several severely obese individuals may possess certain ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Human kidney predominant protein, NCU-G1, is a highly conserved protein with an unknown biological function. Initially described as a nuclear protein, it was later shown to be a bona fide lysosomal integral membrane protein. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Lipid droplet (LD) coating proteins are essential for the formation and stability of intracellular LDs. Plin2 is an abundant LD coating protein in skeletal muscle, but its importance for muscle function is unclear. We show ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background and aims
Physical activity has preventive as well as therapeutic benefits for overweight subjects. In this study we aimed to examine effects of in vivo exercise on in vitro metabolic adaptations by studying ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Metabolic alterations occurring in cancer cells have been seen to also occur in other tissues than cancerous tissue. For instance, cachexia, peripheral insulin resistance, or both are commonly seen in patients with cancer. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Abstract
Background
Recent studies have highlighted that uncoupling of sarco-/endoplasmic reticulum Ca 2+ -ATPase (SERCA) by sarcolipin (SLN) increases ATP consumption and contributes to heat liberation. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
It has previously been shown that pretreatment of differentiated human skeletal muscle cells (myotubes) with eicosapentaenoic acid (EPA) promoted increased uptake of fatty acids and increased triacylglycerol accumulation, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
In this study we compared fatty acid (FA) metabolism in myotubes established from athletic and sedentary young subjects. Six healthy sedentary (maximal oxygen uptake (VO2max)≤ 46 ml/kg/min) and six healthy athletic ...