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Now showing items 201-300 of 360
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Infections caused by the facultative intracellular bacterial pathogen Piscirickettsia salmonis remains an unsolved problem for the aquaculture as no efficient treatments have been developed. As a result, substantial amounts ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Objective: To assess communication skills training at Nordic pharmacy schools and explore ways for improvement.
Methods: E-mail questionnaires were developed and distributed with the aim to explore current practice and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder (ADHD). The mechanism by which paracetamol ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Traditionally, drug prescription and follow up have been the sole responsibility of physicians. However, interprofessional medication reviews (IMRs) have been developed to prevent drug discrepancies ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
There is increasing evidence of clinically relevant antiinflammatory effects of monoaminergic antidepressants. PubMed and Ovid databases were searched systematically for the use and efficacy of antidepressants in association ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
There are limited data on the differences in the impact of psoriasis between various countries with respect to quality of life (QoL). The aim of this study was to explore the psychosocial health of patients with psoriasis ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Introduction: Good communication skills are essential for pharmacy students to help patients with their medicines. Students' attitudes towards communication skills learning will influence their willingness to engage in ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Two decades of research into the ligand‐dependent modulation of the activity of the peroxisome proliferator‐activated receptor γ (PPARγ) have demonstrated the heterogeneous modes of action of PPARγ ligands, in terms of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
A stereodivergent total synthesis has been executed based on the plausibly misassigned structure of the unusual marine hydrindane mucosin (1). The topological connectivity of the four contiguous all-carbon stereocenters ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The resolution of inflammation is an active process orchestrated by specialized proresolving lipid mediators (SPM) that limit the host response within the affected tissue; failure of effective resolution may lead to tissue ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Molecularly imprinted polymers (MIPs) have been used as useful sorbents in solid-phase extraction for a wide range of molecules and sample matrices. Their unique selectivity can be fine-tuned in the imprinting process and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
A concept integrating sampling and protein digestion is introduced here combining fast and simple fabrication by wax printing on filter paper with trypsin immobilized polymer beads. The paper reactors showed promising ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Lipid droplet (LD) coating proteins are essential for the formation and stability of intracellular LDs. Plin2 is an abundant LD coating protein in skeletal muscle, but its importance for muscle function is unclear. We show ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The dynamics of marine populations are usually forced by biotic and abiotic factors occurring at different intensity levels and time scales. Deriving the time frame within which each factor has a causal influence is important ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Immunocapture-based bottom-up LC–MS is a promising technique for the quantification of low abundant proteins. Magnetic immunocapture beads provide efficient enrichment from complex samples through the highly specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Type 2 diabetes (T2D) is manifested by progressive metabolic impairments in tissues such as skeletal muscle and liver, and these tissues become less responsive to insulin, leading to hyperglycemia. In the present study, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Modulation of complement activity and inhibition of nitric oxide (NO) production by macrophages and dendritic cells may have therapeutic value in inflammatory diseases. Elderberry and elderflower extracts, constituents, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Though nausea and vomiting is very common during pregnancy, no studies have investigated the impact of this condition on the women’s daily lives in a Scandinavian population. The aim of this study ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background: Patients with end-stage renal disease (ESRD) are in need of renal replacement therapy as dialysis and/or transplantation. The prevalence of ESRD and, thus, the need for dialysis are constantly growing. The ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Polypharmacy and inappropriate drug use is associated with negative health outcomes among older people. Various interventions for improving drug treatment have been evaluated, but the majority ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Purpose: To describe the risk of early- and late-onset preeclampsia across pregnancies exposed to antidepressants and to evaluate the impact of timing and length of gestational exposure to antidepressants, particularly ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The major virulence factor of enterotoxigenic Escherichia coli is the heat-labile enterotoxin (LT), an AB5 toxin closely related to the cholera toxin. LT consists of six subunits, the catalytically active A-subunit and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Resolvins, protectins and maresins are individual families of specialized pro-resolving mediators biosynthesized from the dietary n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid. These ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Robust biomarker quantification is essential for the accurate diagnosis of diseases and is of great value in cancer management. In this paper, an innovative diagnostic platform is presented which provides automated molecularly ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Parallel artificial liquid membrane extraction (PALME) is a miniaturized version of liquid–liquid extraction (LLE) and is based on two 96-well plates in a sandwich-like configuration. With a very simple workflow, 96 samples ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Vaginal infections are associated with high recurrence, which is often due to a lack of efficient treatment of complex vaginal infections comprised of several types of pathogens, especially fungi and bacteria. Chitosan, a ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The aim of this work was to prepare and test different pharmaceutical formulations in respect of their potential in relieving dry mouth symptom. Since many of the products available on the market provide only temporary ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Few studies have investigated the drug utilization patterns and factors predicting drug use in pregnant women with migraine. This longitudinal drug utilization study aimed to describe patterns ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”. This ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Vaccine development against extracellular bacteria has been important for the sustainability of the aquaculture industry. In contrast, infections with intracellular pathogens remain largely an unresolved problem. Francisella ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Introduction: Yerba Mate (YM) is a South American plant, rich in polyphenols, saponins, and xanthines, of growing scientific interest because of its metabolic effects. YM has been shown to increase fat utilization during ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
This paper studies the dynamics and stability of a stage-structured (immature/mature) population. The emphasis is on how resource available to the immature stage indirectly regulates the dynamics of the mature stage, where ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Lysine methylation is an important and much-studied posttranslational modification of nuclear and cytosolic proteins but is present also in mitochondria. However, the responsible mitochondrial lysine-specific methyltransferases ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
PD1n-3 DPA is a specialized pro-resolving lipid mediator that displays potent anti-inflammatory properties and pro-resolving bioactivities. Such naturally occurring compounds are of current interest in biomolecular chemistry ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Nanoparticulate systems with an uncharged hydrophilic surface may have a great potential in mucosal drug delivery. In the present study liposomes were coated with hydrophobically modified hydroxyethyl cellulose (HM-HEC) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Secretion of extracellular vesicles (EVs) is a common feature of both eukaryotic and prokaryotic cells. Isolated EVs have been shown to contain different types of molecules, including proteins and nucleic acids, and are ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Keywords: Atlantic cod, Francisella noatunensis, Francisellosis, ClpB, Immunization, Zebrafish
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Several novel oxygenated polyunsaturated lipid mediators biosynthesized from n-3 docosapentaenoic acid were recently isolated from murine inflammatory exudates and human primary cells. These compounds belong to a distinct ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The regioselective synthesis of estrogens and their derivatives continues to be of interest. Most reported syntheses require multistep protocols associated with poor overall yield and lack of regioselectivity. New preparative ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Artemisia afra (Jacq. Ex. Willd), is an indigenous plant in South Africa and other parts of the African continent, where it is used as traditional medicine mostly for respiratory conditions. The objective of this study was ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Although pregnancy is known to cause changes in drug pharmacokinetics, little is known about its impact on serum levels of antipsychotics. In this study we retrospectively assessed 201 routine serum antipsychotic therapeutic ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Background
Maternal alcohol use during pregnancy has repeatedly been associated with development of attention-deficit hyperactivity disorder (ADHD) in the offspring. It is, however not known whether this reflects a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The development of vaccines for aquaculture has been an important milestone in providing a continuous and sustainable production. Most of the vaccines currently on the market for aquaculture include oil as adjuvant. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background: Mycophenolic acid (MPA) is the active immunosuppressive substance in both mycophenolate mofetil and mycophenolate sodium, and it is widely used after organ transplantation. In women, taking MPA is teratogenic ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
A serum test called T50 assesses the overall propensity for calcification of the blood and is associated with cardiovascular outcomes. We aimed to examine T50 over time in kidney transplant recipients and also address any ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background and objective: A comparison of sick leave in pregnancy between countries is difficult as most studies have been conducted in single countries in Scandinavia. The objective of this study was to explore patterns ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Interstitial fibrosis and tubular atrophy (IFTA) associated with interstitial inflammation in non scarred areas (IFTA+i) is associated with poorer graft outcome than inflammation without IFTA or IFTA without inflammation. ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Background: Cardiovascular disease is the leading cause of death in renal transplant recipients. An association between haptoglobin genotype 2-2 and cardiovascular disease has been found in patients with diabetes mellitus ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background: Assessment of glomerular filtration rate (GFR) is important in kidney transplantation. The aim was to develop a kidney transplant specific equation for estimating GFR and evaluate against published equations ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Background: Knowledge about the long-term stability of tablets outside the original container, e.g. as unit-doses, is limited. This leaves the pharmacist with the dilemma of seeking improved patient safety by use of ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Understanding the safety of medication use during pregnancy relies on observational studies: However, confounding in observational studies poses a threat to the validity of estimates obtained from observational data. Newer ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background: Exercise-induced rhabdomyolysis denotes the exertional damage of myocytes with leakage of sarcoplasmic content into the circulation. The purpose of this study was to determine important risk factors for the ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The aim of this paper was to perform a comprehensive characterization of polysaccharides isolated from the interior (IOI) and exterior (IOE) parts of the fungus Inonotus obliquus. Pre-extraction with DCM and MeOH, followed ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Background: Patients with high tacrolimus clearance eliminate more drug within a dose interval compared to those with low clearance. Delays in dosing time will result in transient periods of lower concentrations in high- ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Purpose: To investigate the ability of the propensity score (PS) to reduce confounding bias in the presence of nondifferential misclassification of treatment, using simulations.
Methods: Using an example from the pregnancy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Secreted factors are a key component of stem cell niche and their dysregulation compromises stem cell function. Legumain is a secreted cysteine protease involved in diverse biological processes. Here, we demonstrate that ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Human cytomegalovirus (CMV) infection is a substantial cause of morbidity and mortality in immunocompromised hosts and globally is one of the most important congenital infections. The nucleoside analogue ganciclovir (GCV), ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Electromembrane extraction (EME) is an analytical microextraction technique, where charged analytes (such as drug substances) are extracted from an aqueous sample (such as a biological fluid), through a supported liquid ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
The aim was to evaluate the relationship between maintenance immunosuppression, subclinical tubulo-interstital inflammation and interstitial fibrosis/tubular atrophy (IF/TA) in surveillance biopsies performed in low ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Aims: Tacrolimus is a cornerstone in modern immunosuppressive therapy after kidney transplantation. Tacrolimus dosing is challenged by considerable pharmacokinetic variability, both between patients and over time after ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The decapeptide gonadotropin-releasing hormone, also referred to as luteinizing hormone-releasing hormone with the sequence (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) plays an important role in regulating the reproductive ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Aim: Interleukin-27 (IL-27) is involved in different inflammatory diseases; however, its role in atherosclerosis is unclear. In this study we investigated the expression of IL-27 and its receptor in patients with carotid ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objective: The aim of the study was to explore how home-dwelling elderly who use fall-risk-increasing drugs (FRIDs) perceive their fall risk and how they relate this to their drug use.
Design, setting and subjects: A ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The Bacillus cereus group of bacteria includes seven closely related species, three of which, B. anthracis, B. cereus and B. thuringiensis, are pathogens of humans, animals and/or insects. Preliminary investigations into ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objectives: Pregnancy may cause changes in drug disposition, dose requirements and clinical response. For lithium, changes in disposition during pregnancy have so far been explored in a single-dose study on 4 participants ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background and aims
Physical activity has preventive as well as therapeutic benefits for overweight subjects. In this study we aimed to examine effects of in vivo exercise on in vitro metabolic adaptations by studying ...
Use of medicines, adherence and attitudes to medicines among persons with chronic spinal cord injury
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Objectives: To describe the use of medicines and adherence among persons with spinal cord injury (SCI). Further, to examine the influence of pain, spasms and beliefs about medicines on adherence.
Methods: Persons (18 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objective: To assess the relative effectiveness and cost-effectiveness of seven new drugs (cobimetinib, dabrafenib, ipilimumab, nivolumab, pembrolizumab, trametinib and vemurafenib) used for treatment of patients with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objective: To estimate associations of progestin-only contraceptives with persistent pelvic girdle pain 18 months after delivery. Methods Prospective population based cohort study during the years 2003–2011. We included ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The overall aim of the present paper was to develop fluoride loaded nanoparticles based on the biopolymers chitosan, pectin, and alginate, for use in dental delivery. First, the preparation of nanoparticles in the presence ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The efficacy of treatments for oral ailments is often challenged by a low residence time of the conventional pharmaceutical formulations in the oral cavity. The residence time in the oral cavity could be improved by using ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The efficacy of treatments of oral ailments is often challenged by a low residence time of the conventional pharmaceutical formulations in the oral cavity, which could be improved by using bioadhesive formulations. This ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Context: Recreational drug toxicity is frequent. Availability of new psychoactive substances is steadily increasing. However, data with verified analyses from clinical settings are limited. To evaluate the impact of novel ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Purpose of Review: Administrative claims databases, which collect reimbursement-related information generated from healthcare encounters, are increasingly used to evaluate medication safety in pregnancy. We reviewed the ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2016)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
The use of herbal medicines for health prevention and ailments is an increasing trend worldwide. Women in pregnancy are no exception; the reported prevalence of herbal medicine use in pregnancy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
There is no standardized procedure or consensus to which tests should be performed to judge compatibility/incompatibility of intravenous drugs. The purpose of this study was to establish and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Specialized pro-resolving lipid mediators are biosynthesized during the resolution phase of acute inflammation from n-3 polyunsaturated fatty acids. Recently, the isolation and identification of the four novel mediators ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Several studies have reported age-associated changes in DNA methylation in the first few years of life and in adult populations, but the extent of such changes during childhood is less well ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Background/Objectives: Cardiovascular (CV) disease is the leading cause of death after renal transplantation. Marine n-3 polyunsaturated fatty acids (PUFAs) exert potential cardio-protective metabolic effects and might ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The neuropeptide oxytocin (OT) is associated with a plethora of social behaviors, and is a key topic at the intersection of psychology and biology. However, tools for measuring OT are still not fully developed. We describe ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Zanthoxylum heitzii (Rutaceae) (olon) is used in traditional medicine in Central and West Africa to treat malaria. To identify novel compounds with anti-parasitic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Mental disorders strongly influence work capability in young adults, but it is not clear which disorders that are most strongly associated with sick leave, and which diagnoses that are stated on the sick leave ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Objective This study sought to determine whether changes in neurodevelopmental outcomes between 18 and 36 months of age were associated with prenatal exposure to triptan medications, a class of 5-HT receptor agonists used ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Social welfare support runs in families. Recent studies using Nordic registry data have found individual differences in genetic factors to be of substantial importance for medical benefits. However, to date there has been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Perivascular cells (PC) were recently implied as regulators of metastasis and immune cell activity. Perivascular heterogeneity in clinical samples, and associations with other tumor features and outcome, remain largely ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Bradykinin is an important mediator in blood pressure regulation, ischemic precondition and capillary leakage, allergy, anaphylaxis, inflammation, and nociception, at least partly via the generation of nitric oxide (NO). ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Nature Index analysis 2014 rates India at the 13th place for its high-quality scientific publications. Despite this achievement, several studies have revealed that India is also among the major contrib-utors of articles ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The aim of the present study was to develop a LC-MS/MS-based proteomic analysis method of urinary exosomal proteins that has the potential to discover disease biomarkers. In short, urinary exosomes from healthy subjects ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Phage display screening readily allows for the identification of a multitude of antibody specificities, but to identify optimal lead candidates remains a challenge. Here, we direct the antibody-capsid fusion away from the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Objectives Three studies so far have investigated the effect of prenatal non-steroidal anti-inflammatory drug (NSAID) exposure on birth weight and gestational age. The aim in this study was to evaluate the association of ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Pharmaceutical formulations intended for treatment of xerostomia (dry mouth) should be able to keep the oral mucosa hydrated for a prolonged period of time. The products already existing on the market contain water-soluble ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Drug delivery to the oral cavity poses a significant challenge due to the short residence time of the formulations at the site of action. From this point of view, nanoparticulate drug delivery systems with ability to adhere ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Membrane vesicles (MVs) are spherical particles naturally released from the membrane of Gram-negative bacteria. Bacterial MV production is associated with a range of phenotypes including biofilm formation, horizontal gene ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)
Body composition after kidney transplantation is linked to glucose metabolism, and impaired glucose metabolism is associated with increased risk of cardiovascular events and death. One year after transplantation, we examined ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The use of antibodies in “bottom-up “LC-MS workflows to determine low abundant biological active proteins in complex human samples has increased in recent years: immuno-capture analysis combines the workflow of conventional ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Tacrolimus and sirolimus are important immunosuppressive drugs used in human islet transplantation; however, they are linked to detrimental effects on islets and reduction of long-term graft function. Few studies investigate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
With increased development of medical technology (MT), new challenges emerge related to education and training of pharmacists and other healthcare specialists. Currently, only a few universities in the EU promote MT education ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Mucoadhesive drug therapy destined for localized drug treatment is gaining increasing importance in today’s drug development. Chitosan, due to its known biodegradability, bioadhesiveness and excellent safety profile offers ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)