• English
    • Norsk
  • English 
    • English
    • Norsk
  • Administration
Search 
  •   Home
  • Det matematisk-naturvitenskapelige fakultet
  • Farmasøytisk institutt
  • Farmasøytisk institutt
  • Search
  •   Home
  • Det matematisk-naturvitenskapelige fakultet
  • Farmasøytisk institutt
  • Farmasøytisk institutt
  • Search
JavaScript is disabled for your browser. Some features of this site may not work without it.

Search

Show Advanced FiltersHide Advanced Filters

Filters

Use filters to refine the search results.

Now showing items 101-200 of 348

  • Sort Options:
  • Relevance
  • Title Asc
  • Title Desc
  • Issue Date Asc
  • Issue Date Desc
  • Results Per Page:
  • 5
  • 10
  • 20
  • 40
  • 60
  • 80
  • 100
Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose—a randomized controlled trial 
Skulberg, Arne Kristian; Åsberg, Anders; Zare, Hasse Khiabani; Røstad, Hilde; Tylleskär, Ida; Dale, Ola (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
Background and aims Intranasal (i.n.) naloxone is an established treatment for opioid overdose. Anyone likely to witness an overdose should have access to the antidote. We aimed to determine whether an i.n. formulation ...
Interpreting non-linear drug diffusion data: Utilizing Korsmeyer-Peppas model to study drug release from liposomes 
Wu, Iren Yeeling; Bala, Sonali; Skalko-Basnet, Natasa; Di Cagno, Massimiliano Pio (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
The aim of this work was to clarify the dynamics behind the influence of ionic strength on the changes in drug release from large unilamellar vesicles (LUVs). For this purpose, we have investigated the transport of two ...
Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward 
Lea, Marianne; Mowe, Morten; Mathiesen, Liv; Kvernrød, Kristin; Skovlund, Eva; Molden, Espen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background Knowledge of risk factors for drug-related hospitalizations (DRHs) is limited. Aim To examine the prevalence of DRHs and the relationships between DRHs and various variables in multimorbid patients admitted ...
Studying the effect of solubilizing agents on drug diffusion through the unstirred water layer (UWL) by localized spectroscopy 
Di Cagno, Massimiliano Pio; Stein, Paul C (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
An experimental/computational approach has been successfully applied in order to study the effect of solubilizing vehicles (cyclodextrins and liposomes) on the passive diffusion of four active pharmaceutical ingredients ...
The EKiTE network (epidemiology in kidney transplantation - a European validated database): an initiative epidemiological and translational European collaborative research 
Lorent, M.; Foucher, Y.; Kerleau, K.; Brouard, S.; Baayen, C.; Lebouter, S.; Naesens, M.; Bestard Matamoros, O.; Åsberg, A.; Giral, M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background Kidney transplantation is considered to be the treatment of choice for people with end-stage renal disease (ESRD). However, due to the shortage of available organs and the increase in the ESRD ...
Risk perception, beliefs about medicines and medical adherence among pregnant and breastfeeding women with migraine: findings from a cross-sectional study in Norway 
Amundsen, Siri; Øvrebø, Torunn Gudmestad; Amble, Netta Marie Skretteberg; Poole, Anne Christine; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Objectives To examine risk perception, beliefs about migraine medications and medical adherence among pregnant and breastfeeding women with migraine. Design and setting Cross-sectional study conducted in Norway from ...
Perceived sensitivity to medicines: a study among chronic medicine users in Norway 
Svensberg, Karin; Nordeng, Hedvig Marie Egeland; Gaffari, Sahar; Faasse, Kate; Horne, Rob; Lupattelli, Angela (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background Little is known about patients’ Perceived Sensitivity to Medicines (PSM), “the belief that one is especially sensitive to the actions and side effects of medicines”. Objective (i) To explore the extent of and ...
Collagen from Turkey (Meleagris gallopavo) tendon: A promising sustainable biomaterial for pharmaceutical use 
Grønlien, Krister Gjestvang; Pedersen, Mona Elisabeth; Sanden, Karen Wahlstrøm; Høst, Vibeke; Karlsen, Jan; Tønnesen, Hanne Hjorth (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Collagen is the major fibrillar component and protein in both human and animal connective tissue. It is applied in medical preparations, e.g. wound dressings and tissue engineering. Meat and poultry production industries ...
CalY is a major virulence factor and a biofilm matrix protein 
Candela, Thomas; Fagerlund, Annette; Buisson, Christophe; Gilois, Nathalie; Kolstø, Anne-Brit; Økstad, Ole Andreas Løchen; Aymerich, Stephane; Nielsen-LeRoux, Christina; Lereclus, Didier; Gohar, Michel (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
The extracellular biofilm matrix often contains a network of amyloid fibers which, in the human opportunistic pathogen Bacillus cereus , includes the two homologous proteins TasA and CalY. We show here, in the closely ...
Identification of potential carcinogenic and chemopreventive effects of prescription drugs: A protocol for a Norwegian registry-based study 
Kulle, Bettina; Støer, Nathalie Charlotte; Martinsen, Jan Ivar; Ursin, Giske; Weiderpass, Elisabete; Thoresen, G. Hege; Debernard, Karen A. Boldingh; Karlstad, Øystein; Pottegard, Anton; Friis, Søren (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Surveillance of unintended effects of pharmaceuticals (pharmacovigilance or drug safety) is crucial, as knowledge of rare or late side effects is limited at the time of the introduction of new medications into the market. ...
Experiences of Kurdish immigrants with the management of type 2 diabetes: a qualitative study from Norway 
Abuelmagd, Walaa Metwally Ali Abdalaah; Osman, Bavi Botan; Håkonsen, Helle; Jenum, Anne Karen; Toverud, Else-Lydia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Objective: To explore the experiences of immigrant Kurdish patients in Oslo, Norway, related to the management of type 2 diabetes mellitus (T2DM). Design: A qualitative study with focus group interviews. Setting: ...
Immunocapture sample clean-up in determination of low abundant protein biomarkers-a feasibility study of peptide capture by anti-protein antibodies 
Levernæs, Maren Christin Stillesby; Farhat, Bassem; Oulie, Inger; Abdullah, Sazan S.; Paus, Elisabeth; Reubsaet, Leon; Halvorsen, Trine Grønhaug (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Immunocapture in mass spectrometry based targeted protein analysis using a bottom-up workflow is nowadays mainly performed by target protein extraction using anti-protein antibodies followed by tryptic digestion. Already ...
Efficacy and Safety of Empagliflozin in Renal Transplant Recipients With Posttransplant Diabetes Mellitus 
Strøm Halden, Thea Anine; Kvitne, Kine Eide; Midtvedt, Karsten; Rajakumar, Laavanyaah; Robertsen, Ida; Brox, Jan; Bollerslev, Jens; Hartmann, Anders; Åsberg, Anders; Jenssen, Trond Geir (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
OBJECTIVE Sodium–glucose cotransporter 2 (SGLT2) inhibitors have lately become the recommended treatment in patients with type 2 diabetes and high cardiovascular risk. Patients with posttransplant diabetes mellitus (PTDM) ...
Bacillus thuringiensis CbpA is a collagen binding cell surface protein under c-di-GMP control 
Finke, Sarah; Fagerlund, Annette; Smith, Veronika; Krogstad, Veronica; Zhang, Mimmi; Saragliadis, Athanasios; Linke, Dirk; Nielsen-Leroux, Christina; Økstad, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Cyclic diguanylate (c-di-GMP) signalling affects several cellular processes in Bacillus cereus group bacteria including biofilm formation and motility, and CdgF was previously identified as a diguanylate cyclase promoting ...
Mucoadhesive buccal films based on a graft co-polymer – A mucin-retentive hydrogel scaffold 
Alopaeus, Julia Fredrika; Hellfritzsch, Marie; Gutowski, Tobias; Scherließ, Regina; Almeida, Andreia F; Sarmento, Bruno; Skalko-Basnet, Natasa; Tho, Ingunn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
From a patient-centric perspective, oromucosal drug delivery is highly attractive due to the ease of administration without the need of swallowing, and improved patient safety. The aim of the presented work was to prepare ...
Analyzing Missing Data in Perinatal Pharmacoepidemiology Research: Methodological Considerations to Limit the Risk of Bias 
Lupattelli, Angela; Wood, Mollie; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Pharmacoepidemiological studies on the safety of medication during pregnancy are all susceptible to missing data (ie, data that should have been recorded but for some reason were not). Missing data are ubiquitous, irrespective ...
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model 
Pischke, Søren; Hestenes, Siv Merete; Johansen, Harald Thidemann; Fure, Hilde; Bugge, Jan F; Espinoza, Andreas Westenvik; Skulstad, Helge; Edvardsen, Thor; Fosse, Erik; Mollnes, Tom Eirik; Halvorsen, Per Steinar; Nielsen, Erik Waage (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Introduction Right ventricular (RV) myocardial dysfunction is a common feature in septic shock. It can worsen outcome, but the etiology is poorly understood. Pulmonary artery hypertension (PAH) plays a part in the ...
Cyclopropanation–ring expansion of 3-chloroindoles with α-halodiazoacetates: novel synthesis of 4-quinolone-3-carboxylic acid and norfloxacin 
Peeters, Sara; Berntsen, Linn Neerbye; Rongved, Pål; Bonge-Hansen, Tore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
We present a short and efficient way of synthesizing two synthetically versatile 4-quinolone-3-carboxylate building blocks by cyclopropanation-ring expansion of 3-chloroindoles with α-halodiazoacetates as the key step. ...
A twin study of cigarette and snus initiation and quantity of use in Norwegian Adult Twins 
Kendler, Kenneth S.; Aggen, Steven H.; Gillespie, Nathan; Czajkowski, Nikolai Olavi; Ystrøm, Eivind; Reichborn-Kjennerud, Ted (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
While snus has been the focus of increasing public health interest, twin studies have examined neither sources of individual variation for its use nor the sources of resemblance between snus and cigarette use. Twins from ...
Paternal antidepressant use as a negative control for maternal use: assessing familial confounding on gestational length and anxiety traits in offspring 
Cohen, Jacqueline Mallory; Wood, Mollie; Hernandez-Diaz, Sonia; Ystrøm, Eivind; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background Maternal antidepressant use in pregnancy has been associated with both shorter gestational length and child anxiety. We employed paternal antidepressant use as a negative-control exposure to indirectly assess ...
Bacillus cereus biofilm formation on central venous catheters of hospitalised cardiac patients 
Ikram, Samman; Heikal, Adam; Finke, Sarah; Hofgaard, Antje; Rehman, Yasir; Sabri, Anjum Nasim; Økstad, Ole Andreas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Formation of bacterial biofilms is a risk with many in situ medical devices. Biofilm-forming Bacillus species are associated with potentially life-threatening catheter-related blood stream infections in immunocompromised ...
Undiagnosed cardiovascular disease prior to cardiovascular death in individuals with severe mental illness 
Heiberg, Ina Heidi; Jacobsen, Bjarne K.; Balteskard, Lise; Bramness, Jørgen Gustav; Næss, Øyvind; Ystrøm, Eivind; Reichborn-Kjennerud, Ted; Hultman, Christina M.; Nesvåg, Ragnar; Høye, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Objective To examine whether individuals with schizophrenia (SCZ) or bipolar disorder (BD) had equal likelihood of not being diagnosed with cardiovascular disease (CVD) prior to cardiovascular death, compared to individuals ...
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation 
Pettersen, Ina Katrine Nitschke; Tusubira, Deusdedit; Ashrafi, Hanan; Dyrstad, Sissel Elisabeth; Hansen, Lena; Liu, Xiao-Zheng; Hodneland, Linn I.; Løvsletten, Nils Gunnar; Berge, Kjetil; Wergedahl, Hege; Bjørndal, Bodil; Fluge, Øystein; Bruland, Ove; Rustan, Arild; Halberg, Nils; Røsland, Gro Vatne; Berge, Rolf Kristian; Tronstad, Karl Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Fatty acid oxidation is a central fueling pathway for mitochondrial ATP production. Regulation occurs through multiple nutrient- and energy-sensitive molecular mechanisms. We explored if upregulated mRNA expression of the ...
Emulsion Stability of Different Intravenous Propofol Formulations in Simulated Co-Administration with Remifentanil Hydrochloride 
Niklas, Nilsson; Katerina, Nezvalova-Henriksen; Tho, Ingunn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background Propofol and remifentanil often need to be co-administered via the same intravenous catheter line, which predisposes to potential compatibility issues. Our aim was to determine and compare the emulsion stability ...
Synthesis of both enantiomers of the docosahexaenoic acid ester of 13-hydroxyoctadecadienoic acid (13-DHAHLA) 
Vik, Anders; Hansen, Trond Vidar; Kuda, Ondrej (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Recently, several different classes of endogenous lipids have been reported that display antidiabetic and anti-inflammatory effects. Due to their minute presence in human samples, access to synthetic material of each ...
Associations between maternal depressive symptoms and risk for offspring early-life psychopathology: the role of genetic and non-genetic mechanisms 
Gjerde, Line C.; Eilertsen, Espen Moen; Hannigan, Laurie; Eley, Thalia C.; Røysamb, Espen; Reichborn-Kjennerud, Ted; Rijsdijk, Frühling V.; McAdams, Tom A.; Ystrøm, Eivind (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background Although maternal depressive symptoms are robustly associated with offspring early-life psychopathology symptoms, it is not clear which potential mechanisms are at play. We aimed to estimate the relative ...
High intensity interval training ameliorates mitochondrial dysfunction in the left ventricle of mice with type 2 diabetes 
Bækkerud, Fredrik Hjulstad; Salerno, Simona; Ceriotti, Paola; Morland, Cecilie; Storm-Mathisen, Jon; Bergersen, Linda Hildegard; Høydal, Morten; Catalucci, Daniele; Stølen, Tomas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Both human and animal studies have shown mitochondrial and contractile dysfunction in hearts of type 2 diabetes mellitus (T2DM). Exercise training has shown positive effects on cardiac function, but its effect on the ...
Characterization of Inulin-Type Fructan from Platycodon grandiflorus and Study on Its Prebiotic and Immunomodulating Activity 
Pang, Di-Jiang; Huang, Chao; Chen, Mei-Ling; Chen, Yu-Long; Fu, Yu-Ping; Paulsen, Berit Smestad; Rise, Frode; Zhang, Bing-Zhao; Chen, Zheng-Li; Jia, Ren-Yong; Li, Li-Xia; Song, Xu; Feng, Bin; Ni, Xue-Qin; Yin, Zhong-Qiong; Zou, Yuan-Feng (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Platycodon grandiflorus is a plant widely used in traditional Chinese medicine, of which polysaccharides are reported to be the main components responsible for its bio-functions. In this work, the inulin-type fructan (PGF) ...
Women’s Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists 
Ceulemans, Michael; Lupattelli, Angela; Nordeng, Hedvig Marie Egeland; Odalovic, Marina; Twigg, Michael J.; Foulon, Veerle (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background: During pregnancy, women might weigh the benefits of treatment against potential risks to the unborn child. However, non-adherence to necessary treatment can adversely affect both mother and child. To optimize ...
Vitamin D as a risk factor for patient survival after kidney transplantation: A prospective observational cohort study 
Thorsen, Inga Strand; Bleskestad, Inger Hjørdis; Åsberg, Anders; Hartmann, Anders; Skadberg, Øyvind; Brede, Cato; Ueland, Thor; Pasch, Andreas; Reisæter, Anna Varberg; Gøransson, Lasse (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background Short‐term survival after kidney transplantation is excellent, but long‐term survival remains low and is equivalent to non‐end‐stage renal disease patients with many invasive malignancies. The aim of the study ...
A Method for Direct Monitoring of Atorvastatin Adherence in Cardiovascular Disease Prevention: Quantification of the Total Exposure to Parent Drug and Major Metabolites Using 2-Channel Chromatography and Tandem Mass Spectrometry 
Vethe, Nils Tore; Munkhaugen, John; Andersen, Anders Mikal; Husebye, Einar; Bergan, Stein (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background: Low adherence to statin therapy remains a public health concern associated with poor prognosis in cardiovascular disease patients. A feasible method for statin adherence monitoring in clinical practice has ...
A novel direct method to determine adherence to atorvastatin therapy in patients with coronary heart disease 
Kristiansen, Oscar; Vethe, Nils Tore; Fagerland, Morten; Bergan, Stein; Munkhaugen, John; Husebye, Einar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Aims Objective methods to monitor statin adherence are needed. We have established a liquid chromatography–tandem mass spectrometry assay for quantification of atorvastatin and its metabolites in blood. This study aimed ...
Identification and Assessment of Drug-User Groups Among Nightlife Attendees: Self-Reports, Breathalyzer-Tests and Oral Fluid Drug Tests 
Bretteville-Jensen, Anne Line; Burdzovic, Jasmina; Gjersing, Linn; Øiestad, Elisabeth Leere; Gjerde, Halvard (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Background and Objectives: Even though nightlife studies with potentially intoxicated participants provide the much needed information on drug use, they face additional methodological challenges. This study aimed to explore ...
Vesicles From Vibrio cholerae Contain AT-Rich DNA and Shorter mRNAs That Do Not Correlate With Their Protein Products 
Langlete, Petter; Krabberød, Anders Kristian; Winther-Larsen, Hanne Cecilie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Extracellular vesicles secreted by Gram-negative bacteria have proven to be important in bacterial defense, communication and host-pathogen relationships. They resemble smaller versions of the bacterial mother cell, with ...
Increased glycolysis and higher lactate production in hyperglycemic myotubes 
Lund, Jenny; Ouwens, DM; Wettergreen, Marianne; Bakke, Siril Skaret; Thoresen, G. Hege; Aas, Vigdis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial ...
Design, synthesis and biological evaluation of 6‐substituted quinolines derived from cabozantinib as c‐Met inhibitors 
Lien, Vegard Torp; Pettersen, Solveig; Haugen, Mads Haugland; Olberg, Dag Erlend; Mælandsmo, Gunhild Mari; Klaveness, Jo (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Based on the cabozantinib scaffold, novel c‐Met inhibitors were rationalized from the limited knowledge of structure‐activity relationships for the quinoline 6‐position. Emphasis was given to modifications capable of ...
A mitochondria-targeted fatty acid analogue influences hepatic glucose metabolism and reduces the plasma insulin/glucose ratio in male Wistar rats 
Lindquist, Carine; Bjørndal, Bodil; Bakke, Hege Gilbø; Slettom, Grete; Karoliussen, Marie; Rustan, Arild; Thoresen, G. Hege; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
A fatty acid analogue, 2-(tridec-12-yn-1-ylthio)acetic acid (1-triple TTA), was previously shown to have hypolipidemic effects in rats by targeting mitochondrial activity predominantly in liver. This study aimed to determine ...
Matrix assisted ionization mass spectrometry in targeted protein analysis – an initial evaluation 
Skjærvø, Øystein; Trimpin, Sarah; Halvorsen, Trine Grønhaug (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Rationale Matrix‐assisted ionization (MAI) is a relatively new ionization technique for analysis by mass spectrometry (MS). The technique is simple and has been shown to be less influenced by matrix effects than e.g. ...
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules 
Grevys, Algirdas; Nilsen, Jeannette; Sand, Kine Marita Knudsen; Daba, Muluneh Bekele; Øynebråten, Inger; Bern, Malin C.; McAdam, Martin Berner; Foss, Stian; Schlothauer, Tilman; Michaelsen, Terje Einar; Christianson, Gregory J.; Roopenian, Derry C.; Blumberg, Richard S.; Sandlie, Inger; Andersen, Jan Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Albumin and IgG have remarkably long serum half-lives due to pH-dependent FcRn-mediated cellular recycling that rescues both ligands from intracellular degradation. Furthermore, increase in half-lives of IgG and albumin-based ...
Affordability of commonly prescribed antibiotics in a large tertiary teaching hospital in Ethiopia: a challenge for the national drug policy objective 
Gutema, Girma; Engidawork, Ephrem (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Objective In national drug policies of many countries, ensuring availability and affordability of essential medicines is indicated among the major policy objectives. To achieve the objectives, countries ...
Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL) 
Hjelmesæth, Jøran; Åsberg, Anders; Andersson, Shalini; Sandbu, Rune; Robertsen, Ida; Johnson, Line Kristin; Angeles, Philip Carlo Soriano; Hertel, Jens Kristoffer; Skovlund, Eva; Heijer, Maria; Ek, Anna-Lena; Krogstad, Veronica; Karlsen, Tor-Ivar; Christensen, Hege Staaland; Andersson, Tommy B; Karlsson, Cecilia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Introduction Roux-en-Y gastric bypass (GBP) is associated with changes in cardiometabolic risk factors and bioavailability of drugs, but whether these changes are induced by calorie restriction, the weight loss or surgery ...
Ethnobotany of dioecious species: Traditional knowledge on dioecious plants in India 
Gopalakrishnan Saroja, Seethapathy; Kaliamoorthy, Ravikumar; Paulsen, Berit Smestad; de Boer, Hugo; Wangensteen, Helle (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Ethnopharmacological relevance: More than 15,000 angiosperm species are dioecious, i.e., having distinct male and female individual plants. The allocation of resources between male and female plants is different, and also ...
Multiple challenges of antibiotic use in a large hospital in Ethiopia – a ward-specific study showing high rates of hospital-acquired infections and ineffective prophylaxis 
Gutema, Girma; Håkonsen, Helle; Engidawork, Ephrem; Toverud, Else-Lydia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background This project aims to study the use of antibiotics in three clinical wards in the largest tertiary teaching hospital in Ethiopia for a period of 1 year. The specific aims were to assess the ...
Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles 
Prandina, Anthony; Herfindal, Lars; Radix, S; Rongved, Pål; Doskeland, Stein Ove; Le Borgne, Marc; Perret, F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Phenazine is known to regroup planar nitrogen-containing heterocyclic compounds. It was used here to enhance the bioavailability of the biologically important compound iodinin, which is near insoluble in aqueous solutions. ...
Characterization and prebiotic activity in vitro of inulin-type fructan from Codonopsis pilosula roots 
Fu, Yu-Ping; Li, Li-Xia; Zhang, Bing-Zhao; Paulsen, Berit Smestad; Yin, Zhong-Qiong; Huang, Chao; Feng, Bin; Chen, Xing-Fu; Jia, Ren-Rong; Song, Xu; Ni, Xue-Qin; Jing, Bo; Wu, Fa-ming; Zou, Yuan-Feng (Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)
The inulin-type fructan was obtained by DEAE anion exchange chromatography from C. pilosula Nannf. var. modesta (Nannf.) L. T. Shen, after optimized extract condition, which was established by response surface methodology, ...
Determination of the Low-Abundant Protein Biomarker hCG from Dried Matrix Spots using Immunocapture and Nano Liquid Chromatography Mass Spectrometry 
Rosting, Cecilie; Tran, Elin Vyvy; Gjelstad, Astrid; Halvorsen, Trine Grønhaug (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Using LC-MS/MS for determination of low-abundance protein biomarkers from dried blood spots is challenging due to the combination of low biomarker levels (low pM-level) and small sample volumes (typically <50 μL). In the ...
Volumetric absorptive MicroSampling vs. other blood sampling materials in LC-MS-based protein analysis - preliminary investigations 
Andersen, Ida Kristine Lysgaard; Rosting, Cecilie; Gjelstad, Astrid; Halvorsen, Trine Grønhaug (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
The aim was to evaluate the performance of different microsampling materials in LC–MS-based protein analysis. The evaluated materials were the Volumetric Absorptive MicroSampling (VAMS) device, the pure cellulose sampling ...
The novel adipokine WISP1 associates with insulin resistance and impairs insulin action in human myotubes and mouse hepatocytes 
Hörbelt, Tina; Tacke, Christopher; Markova, Mariya; Herzfeld de Wiza, Daniella; Van de Velde, Frederique; Bekaert, Marlies; Van Nieuwenhove, Yves; Hornemann, Silke; Rödiger, Maria; Seebeck, Nicole; Friedl, Elisabeth; Jonas, Wenke; Thoresen, G. Hege; Kuss, Oliver; Rosenthal, Anke; Lange, Volker; Pfeiffer, Andreas F.H.; Schürmann, Annette; Lapauw, Bruno; Rudovich, Natalia; Pivovarova, Olga; Ouwens, D. Margriet (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Aims/hypothesis: Wingless-type (Wnt) inducible signalling pathway protein-1 (WISP1) has been recently identified as a proinflammatory adipokine. We examined whether WISP1 expression and circulating levels are altered in ...
Potential for More Rational Use of Antibiotics in Hospitalized Children in a Country with Low Resistance-Data from Eight Point Prevalence Surveys 
Thaulow, Chistian Magnus; Berild, Dag; Eriksen, Beate Horsberg; Myklebust, TÅ; Blix, Hege Salvesen (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Abstract BACKGROUND: Antimicrobial resistance (AMR) is low in Norway, but to prevent an increase the Norwegian Government has launched a National Strategy including a 30% reduction of broad-spectrum antibiotics (BSA) in ...
Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate Pseudomonas aeruginosa PASS1 With Zebrafish 
Kumar, Sheemal S.; Tandberg, Julia Isabel; Penesyan, Anahit; Elbourne, Liam D. H.; Suarez-Bosche, Nadia; Don, Emily; Skadberg, Eline Supannee Setu; Fenaroli, Federico; Cole, Nicholas; Winther-Larsen, Hanne Cecilie; Paulsen, Ian T. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Pseudomonas aeruginosa is a significant cause of mortality in patients with cystic fibrosis (CF). To explore the interaction of the CF isolate P. aeruginosa PASS1 with the innate immune response, we have used Danio rerio ...
Interpreting oral fluid drug results in prisoners: monitoring current drug intake and detection times for drugs self-administered prior to detention 
Øiestad, Elisabeth Leere; Krabseth, Hege-Merete; Huestis, Marilyn A.; Skulberg, Andreas; Vindenes, Vigdis (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Purpose: Although urine is the most common matrix for prisoner drug testing, oral fluid offers a possible alternative. Identifying new drug intake by a prisoner results in negative sanctions. Detection times in oral fluid ...
Synthesis and biological evaluations of marine oxohexadecenoic acids: PPARα/γ dual agonism and anti-diabetic target gene effects 
Sæther, Thomas; Paulsen, Steinar M; Tungen, Jørn Eivind; Vik, Anders; Aursnes, Marius; Holen, Torgeir; Hansen, Trond Vidar; Nebb, Hilde Irene (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Obesity and associated disorders such as metabolic syndrome and type 2 diabetes (T2D) have reached epidemic proportions. Several natural products have been reported as Peroxisome Proliferator-Activated Receptor (PPAR) ...
p38 differentially regulates ERK, p21, and mitogenic signalling in two pancreatic carcinoma cell lines 
Aasrum, Monica; Thoresen, G. Hege; Christoffersen, Thoralf; Brusevold, Ingvild Johnsen (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Whereas the p38 MAP kinase has largely been associated with anti-proliferative functions, several observations have indicated that it may also have positive effects on proliferation. In hepatocytes, we have found that p38 ...
Paricalcitol supplementation during the first year after kidney transplantation does not affect calcification propensity score 
Ussif, Amin; Pihlstrøm, Hege; Pasch, Andreas; Holdaas, Hallvard; Hartmann, Anders; Smerud, Knut; Åsberg, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background Cardiovascular complications are common in kidney transplant patients and calcification propensity of blood, measured as T50, is associated with cardiovascular outcomes. Paricalcitol supplementation ...
Rheological and thermal properties of suspensions of microcapsules containing phase change materials 
Cao, Vinh Duy; Salas Bringas, Carlos; Schüller, Reidar Barfod; Szczotok-Piechaczek, Anna Maria; Hiorth, Marianne; Carmona, Manuel; Rodriguez, Juan F.; Kjøniksen, Anna-Lena (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
The thermal and rheological properties of suspensions of microencapsulated phase change materials (MPCM) in glycerol were investigated. When the microcapsule concentration is raised, the heat storage capacity of the ...
Smoking and Obesity as Risk Factors in Frontotemporal Dementia and Alzheimer's Disease: The HUNT Study 
Eid, Hege Rasmussen; Rosness, Tor Atle; Bosnes, Ole; Salvesen, Øyvind; Knutli, Marlen; Stordal, Eystein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background: Few studies have assessed smoking and obesity together as risk factors for frontotemporal dementia (FTD) and Alzheimer’s disease (AD). Objective: To study smoking and obesity as risk factors for FTD and AD. ...
Authentication of Garcinia fruits and food supplements using DNA barcoding and NMR spectroscopy 
Gopalakrishnan Saroja, Seethapathy; Tadesse, Margey; Santhosh Kumar, JU; Gunaga, Srikanth V.; Vasudeva, Ramesh; Malterud, Karl Egil; Ramanan, Uma Shaanker; de Boer, Hugo; Gudasalamani, Ravikanth; Wangensteen, Helle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Garcinia L. (Clusiaceae) fruits are a rich source of (−)-hydroxycitric acid, and this has gained considerable attention as an anti-obesity agent and a popular weight loss food supplement. In this study, we assessed ...
Agreement between paternal self-reported medication use and records from a national prescription database 
Cohen, Jacqueline M.; Wood, Mollie; Hernandez-Diaz, Sonia; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
PurposeFather's medication use is of interest in fertility studies and as negative control exposures in pregnancy medication safety studies. We sought to compare self-report to prescription records to understand how reliably ...
Development of ADHD symptoms in preschool children: Genetic and environmental contributions 
Eilertsen, Espen Moen; Gjerde, Line C.; Kendler, Kenneth S.; Røysamb, Espen; Aggen, Steven H.; Gustavson, Kristin; Reichborn-Kjennerud, Ted; Ystrøm, Eivind (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
We examined genetic and environmental contributions to the development of symptoms of attention-deficit/hyperactivity disorder (ADHD) in preschool children. ADHD symptoms in siblings at 1.5, 3, and 5 years of age were ...
The European Renal Association - European Dialysis and Transplantation Association (ERA-EDTA) registry Annual Report 2015: a summary 
Kramer, Anneke; Pippias, Maria; Noordzij, Marlies; Stel, VS; Afentakis, Nikolaos; Ambühl, Patrice M; Andrusev, AM; Fuster, EA; Monzon, Federico E; Åsberg, Anders; Barbullushi, M; Bonthius, Marjolein; Caskey, Fergus J; De La Nuez, Pablo Castro; Cernevskis, Harijs; des Grottes, Jean-Marin; Garneata, Liliana; Golan, Eliezer; Hemmelder, Marc H.; Ioannou, Kyriakos; Jarraya, Facial; Kolesnyk, Mykola; Komissarov, Kirill; Lassalle, Mathilde; Macário, Fernando; Mahillo-Duran, Beatriz; de Francisco, A; Pálsson, Runólfur; Pechter, Ülle; Resic, Halima; Rutkowski, Boleslaw; De Pablos, Carmen Santiuste; Seyahi, Nurhan; Ogrizovic, Sanja Simic; Roblero, María Fernanda Slon; Spustová, Viera; Stojceva-Taneva, Olivera; Traynor, Jamie P.; Massy, Ziad A.; Jager, Kitty J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background: This article summarizes the European Renal Association – European Dialysis and Transplant Association (ERA-EDTA) Registry’s 2015 Annual Report. It describes the epidemiology of renal replacement therapy (RRT) ...
Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial 
Johansen, Jeanette Schultz; Havnes, Kjerstin; Halvorsen, Kjell H.; Haustreis, Stine-Mari; Skaue, Lillann Wilsgård; Kamycheva, Elena; Mathiesen, Liv; Viktil, Kirsten Kilvik; Granås, Anne Gerd; Garcia, Beate Hennie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Introduction: Drug-related problems (DRPs) are common in the elderly, leading to suboptimal therapy, hospitalisations and increased mortality. The integrated medicines management (IMM) model is a multifactorial interdisciplinary ...
Outcomes in pancreas transplantation with exocrine drainage through a duodenoduodenostomy versus duodenojejunostomy 
Lindahl, Jørn Petter Hanto; Horneland, Rune; Nordheim, Espen; Hartmann, Anders; Aandahl, Einar Martin; Grzyb, Krzysztof; Haugaa, Håkon; Kjøsen, Gisle; Åsberg, Anders; Jenssen, Trond Geir (Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)
Until recently, pancreas transplantation has mostly been performed with exocrine drainage via duodenojejunostomy (DJ). Since 2012, DJ was substituted with duodenoduodenostomy (DD) in our hospital, allowing endoscopic access ...
Revisiting the Children-of-Twins Design: Improving Existing Models for the Exploration of Intergenerational Associations 
McAdams, Tom A; Hannigan, Laurie J; Eilertsen, Espen Moen; Gjerde, Line C.; Ystrøm, Eivind; Rijsdijk, Frühling V (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Datasets comprising twins and their children can be a useful tool for understanding the nature of intergenerational associations between parent and offspring phenotypes. In the present article we explore structural equation ...
Requests for new oral antibiotic prescriptions in children within 2 days: a Norwegian population-based study 
Bergene, Elin Høien; Nordeng, Hedvig Marie Egeland; Rø, Torstein Baade; Steinsbekk, Aslak (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background: Children commonly refuse to take antibiotics, which may induce parents to request new antibiotic prescriptions with different pharmaceutical characteristics. Objectives: To investigate prescription changes ...
The janus face of VEGF in stroke 
Geiseler, Samuel; Morland, Cecilie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
The family of vascular endothelial growth factors (VEGFs) are known for their regulation of vascularization. In the brain, VEGFs are important regulators of angiogenesis, neuroprotection and neurogenesis. Dysregulation of ...
Self-reported perinatal depressive symptoms and postnatal symptom severity after treatment with antidepressants in pregnancy: a cross-sectional study across 12 European countries using the Edinburgh Postnatal Depression Scale 
Lupattelli, Angela; Twigg, Michael J; Zagorodnikova, Ksenia; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Purpose: This study aimed at exploring the prevalence of self-reported antenatal and postnatal depressive symptoms by severity across multiple countries and the association between antidepressant treatment in pregnancy and ...
Prenatal triptan exposure and neurodevelopmental outcomes in 5-year-old children: Follow-up from the Norwegian Mother and Child Cohort Study 
Harris, Gerd Marie Eskerud; Wood, Mollie; Ystrøm, Eivind; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Background Triptans are commonly used to treat migraine headaches, but data on the long‐term safety of these medications during pregnancy are sparse. Triptans have a biologically plausible mechanism for effects on the ...
Incidence Trends of Atopic Dermatitis in Infancy and Early Childhood in a Nationwide Prescription Registry Study in Norway 
Mohn, Cathrine Helene; Blix, Hege Salvesen; Halvorsen, Jon Anders; Nafstad, Per; Valberg, Morten; Lagerløv, Per (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Importance With increasing prevalence of atopic dermatitis (AD) and its manifestation in most countries, together with the supporting evidence of the progression to other atopic phenotypes, AD has developed into a worldwide ...
Maternal Perinatal and Concurrent Anxiety and Mental Health Problems in Early Childhood: A Sibling‐Comparison Study 
Gjerde, Line C.; Eilertsen, Espen Moen; Eley, Thalia C.; McAdams, Tom A.; Reichborn-Kjennerud, Ted; Røysamb, Espen; Ystrøm, Eivind (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Do associations between maternal anxiety symptoms and offspring mental health remain after comparing differentially exposed siblings? Participants were 17,724 offspring siblings and 11,553 mothers from the Norwegian Mother ...
Maternal use of thyroid hormone replacement therapy before, during, and after pregnancy: agreement between self-report and prescription records and group-based trajectory modeling of prescription patterns 
Frank, Anna-Simone Josefine; Lupattelli, Angela; Matteson, David S.; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Purpose: A reliable definition of exposure and knowledge about long-term medication patterns is important for drug safety studies during pregnancy. Few studies have investigated these measures for thyroid hormone replacement ...
Small effort, high impact: Focus on physical activity improves oxygen uptake (VO2peak), quality of life, and mental health after pediatric renal transplantation 
Thorsteinsdottir, Hjørdis; Diseth, Trond H; Lie, Anine; Tangeraas, Trine; Matthews, Iren; Åsberg, Anders; Bjerre, Anna Kristina (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
This study estimates the effects on peak oxygen uptake (VO2 peak), QoL, and mental health after the introduction of an adjusted post‐transplant follow‐up program, that is, early physiotherapy and focus on the importance ...
Elevated 4β‐hydroxycholesterol/cholesterol ratio in anorexianervosa patients 
Hole, Kristine; Heiberg, Petra Lybæk; Gjestad, Caroline; Mehus, Lise Larsen; Rø, Øyvind; Molden, Espen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Recent studies have shown that the cytochrome P450 (CYP) 3A phenotype marker 4β‐hydroxycholesterol/cholesterol (4βOHC/C) ratio is negatively correlated with body weight in healthy volunteers, and that obese patients have ...
Learning the effects of psychotropic drugs during pregnancy using real-world safety data: a paradigm shift toward modern pharmacovigilance 
Lupattelli, Angela; Spigset, Olav; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
The growing evidence on psychotropic drug safety in pregnancy has been possible thanks to the increasing availability of real-world data, i.e. data not collected in conventional randomised controlled trials. Use of these ...
Personality and its relation to the use of alcohol and cigarettes during pregnancy: A multinational study 
Lupattelli, Angela; Rønningen, Elke; Krogsrud, Stine Kleppe; Nordeng, Hedvig Marie Egeland; Ystrøm, Eivind (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
This study explored the impact of women’s personality on drinking and smoking habits before and during pregnancy, using a multinational perspective. Data on maternal personality traits, background information, and alcohol ...
Increased triacylglycerol - Fatty acid substrate cycling in human skeletal muscle cells exposed to eicosapentaenoic acid. 
Løvsletten, Nils Gunnar; Bakke, Siril Skaret; Kase, Eili Tranheim; Ouwens, D. Margriet; Thoresen, G. Hege; Rustan, Arild (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
It has previously been shown that pretreatment of differentiated human skeletal muscle cells (myotubes) with eicosapentaenoic acid (EPA) promoted increased uptake of fatty acids and increased triacylglycerol accumulation, ...
Testing Genetic and Environmental Associations Between Personality Disorders and Cocaine Use: A Population-Based Twin Study 
Gillespie, Nathan A.; Aggen, Steven H.; Gentry, Amanda E.; Neale, Michael Churton; Knudsen, Gun Peggy S.; Krueger, Robert Frederick; South, Susan Carol; Czajkowski, Nikolai Olavi; Nesvåg, Ragnar; Ystrøm, Eivind; Rosenström, Tom Henrik; Torvik, Fartein Ask; Reichborn-Kjennerud, Ted; Kendler, Kenneth Seedman (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Until now, data have not been available to elucidate the genetic and environmental sources of comorbidity between all 10 DSM-IV personality disorders (PDs) and cocaine use. Our aim was to determine which PD traits are ...
Higher lipid turnover and oxidation in cultured human myotubes from athletic versus sedentary young male subjects 
Lund, Jenny; Helle, Siw A.; Li, Yuchuan; Løvsletten, Nils Gunnar; Stadheim, Hans Kristian; Jensen, Jørgen; Kase, Eili Tranheim; Thoresen, G. Hege; Rustan, Arild (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
In this study we compared fatty acid (FA) metabolism in myotubes established from athletic and sedentary young subjects. Six healthy sedentary (maximal oxygen uptake (VO2max)≤ 46 ml/kg/min) and six healthy athletic ...
Adverse family life events during pregnancy and ADHD symptoms in five-year-old offspring 
Rosenqvist, Mina A; Sjölander, Arvid; Ystrøm, Eivind; Larsson, Henrik; Reichborn-Kjennerud, Ted (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background Prenatal exposure to maternal adverse life events has been associated with offspring ADHD, but the role of familial confounding is unclear. We aimed to clarify if adverse life events during pregnancy are ...
Experimental and Modeling Study of Drug Release from HPMC-Based Erodible Oral Thin Films 
Adrover, Alessandra; Varani, Gabriele; Paolicelli, Patrizia; Petralito, Stefania; Di Muzio, Laura; Casadei, Maria Antonietta; Tho, Ingunn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
In this work hydroxypropyl methylcellulose (HPMC) fast-dissolving thin films for oral administration are investigated. Furosemide (Class IV of the Biopharmaceutical Classification System) has been used as a model drug for ...
Utilization of lactic acid in human myotubes and interplay with glucose and fatty acid metabolism 
Lund, Jenny; Aas, Vigdis; Tingstad, Ragna Husby; Van Hees, Alfons; Nikolic, Natasa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular ...
Targeted deletion of the aquaglyceroporin AQP9 is protective in a mouse model of Parkinson's disease 
Stahl, Katja; Rahmani, Soulmaz; Prydz, Agnete; Skauli, Nadia; MacAulay, Nanna; Mylonakou, Maria-Niki; Torp, Reidun; Skare, Øivind; Berg, Torill; Leergaard, Trygve Brauns; Paulsen, Ragnhild Elisabeth; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
More than 90% of the cases of Parkinson's disease have unknown etiology. Gradual loss of dopaminergic neurons of substantia nigra is the main cause of morbidity in this disease. External factors such as environmental toxins ...
Child temperament predicts the adiposity rebound. A 9-year prospective sibling control study 
Vollrath, Margarete E.; Hampson, Sarah E; Peneau, Sandrine; Rolland-Cachera, Marie Francoise; Ystrøm, Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
The goal of this study is to examine the extent to which child temperament predicts the adiposity rebound, a steep increase in the body mass index (BMI) between ages 5 and 7 years. If this increase occurs at an earlier ...
Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity 
Rounge, Trine Ballestad; Umu, Sinan Uğur; Keller, Andreas; Meese, Eckart; Ursin, Giske; Tretli, Steinar; Lyle, Robert; Langseth, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Small non-coding RNAs (sncRNA) are regulators of cell functions and circulating sncRNAs from the majority of RNA classes are potential non-invasive biomarkers. Understanding how common traits influence ncRNA expression is ...
Antibody based affinity capture LC-MS/MS in quantitative determination of proteins in biological matrices 
Halvorsen, Trine Grønhaug; Reubsaet, Leon (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Determination of proteins in complex biological matrices has massive attention and is exploited in many different scientific disciplines. Routinely, proteins are determined using antibody based immuno-metric assays. Although ...
Membrane vesicles from Piscirickettsia salmonis induce protective immunity and reduce development of salmonid rickettsial septicemia in an adult zebrafish model 
Tandberg, Julia Isabel; Oliver, Cristian; Lagos, Leidy; Gaarder, Mona; Yáñez, Alejandro J.; Ropstad, Erik; Winther-Larsen, Hanne Cecilie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Infections caused by the facultative intracellular bacterial pathogen Piscirickettsia salmonis remains an unsolved problem for the aquaculture as no efficient treatments have been developed. As a result, substantial amounts ...
Nordic Pharmacy Schools’ Experience in Communication Skills Training 
Svensberg, Karin Anna Evelina; Björnsdottir, Ingunn; Wallman, Andy; Sporrong, Sofia K (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Objective: To assess communication skills training at Nordic pharmacy schools and explore ways for improvement. Methods: E-mail questionnaires were developed and distributed with the aim to explore current practice and ...
Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD 
Gervin, Kristina; Nordeng, Hedvig; Ystrom, Eivind; Reichborn-Kjennerud, Ted; Lyle, Robert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder (ADHD). The mechanism by which paracetamol ...
Nurses’ and pharmacists’ learning experiences from participating in interprofessional medication reviews for elderly in primary health care - a qualitative study 
Bell, H. T; Granas, A. G; Enmarker, I.; Omli, R.; Steinsbekk, A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background Traditionally, drug prescription and follow up have been the sole responsibility of physicians. However, interprofessional medication reviews (IMRs) have been developed to prevent drug discrepancies ...
Antidepressants have anti-inflammatory effects that may be relevant to dermatology: A systematic review 
Eskeland, Shirin; Halvorsen, Jon Anders; Tanum, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
There is increasing evidence of clinically relevant antiinflammatory effects of monoaminergic antidepressants. PubMed and Ovid databases were searched systematically for the use and efficacy of antidepressants in association ...
Determinants of psychosocial health in psoriatic patients: A multinational study 
Lesner, Karolina; Reich, Adam; Szepietowski, Jacek C.; Dalgard, Florence; Gieler, Uwe; Tomasaragones, Lucia; Lien, Lars; Poot, Francoise; Jemec, Gregor B.; Misery, Laurent; Szabó, Csanád; Linder, Dennis; Sampogna, Francesca; Evers, Andrea W.M.; Halvorsen, Jon Anders; Balieva, Flora Nicol; Lvov, Andrey; Marrón, Servando E.; Altunay, Ilknur K.; Finlay, Andrew Y.; Salek, Sam S.; Kupfer, Jörg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
There are limited data on the differences in the impact of psoriasis between various countries with respect to quality of life (QoL). The aim of this study was to explore the psychosocial health of patients with psoriasis ...
Factors associated with pharmacy students' attitudes towards learning communication skills – A study among Nordic pharmacy students 
Svensberg, Karin Anna Evelina; Brandlistuen, Ragnhild Eek; Björnsdottir, Ingunn; Sporrong, Sofia K (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Introduction: Good communication skills are essential for pharmacy students to help patients with their medicines. Students' attitudes towards communication skills learning will influence their willingness to engage in ...
Structural review of PPARγ in complex with ligands: Cartesian- and dihedral angle principal component analyses of X-ray crystallographic data 
Kaupang, Åsmund; Laitinen, Tuomo; Poso, Antti; Hansen, Trond Vidar (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Two decades of research into the ligand‐dependent modulation of the activity of the peroxisome proliferator‐activated receptor γ (PPARγ) have demonstrated the heterogeneous modes of action of PPARγ ligands, in terms of ...
Instant on-paper protein digestion during blood spot sampling 
Skjærvø, Øystein; Rosting, Cecilie; Halvorsen, Trine Grønhaug; Reubsaet, Leon (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
A concept integrating sampling and protein digestion is introduced here combining fast and simple fabrication by wax printing on filter paper with trypsin immobilized polymer beads. The paper reactors showed promising ...
Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection 
Gobbetti, Thomas; Dalli, Jesmond; Colas, Romain A.; Canova, Donata Federici; Aursnes, Marius; Bonnet, Delphine; Alric, Laurent; Vergnolle, Nathalie; Deraison, Celine; Hansen, Trond Vidar; Serhan, Charles N.; Perretti, Mauro (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The resolution of inflammation is an active process orchestrated by specialized proresolving lipid mediators (SPM) that limit the host response within the affected tissue; failure of effective resolution may lead to tissue ...
Stereopermutation on the Putative Structure of the Marine Natural Product Mucosin 
Antonsen, Simen Gjelseth; Gallantree-Smith, Harrison Christopher; Görbitz, Carl Henrik; Hansen, Trond Vidar; Stenstrøm, Yngve H.; Nolsøe, Jens Mortansson Jelstrup (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
A stereodivergent total synthesis has been executed based on the plausibly misassigned structure of the unusual marine hydrindane mucosin (1). The topological connectivity of the four contiguous all-carbon stereocenters ...
Exploring the peptide retention mechanism in molecularly imprinted polymers 
Rossetti, Cecilia; Ore, Odd Gøran; Sellergren, Börje; Halvorsen, Trine Grønhaug; Reubsaet, Leon (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Molecularly imprinted polymers (MIPs) have been used as useful sorbents in solid-phase extraction for a wide range of molecules and sample matrices. Their unique selectivity can be fine-tuned in the imprinting process and ...
Causal Drivers of Barents Sea Capelin(Mallotus villosus) Population Dynamics on Different Time Scales 
Subbey, Sam; Solvang, Hiroko Kato; Frank, Anna-Simone Josefine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The dynamics of marine populations are usually forced by biotic and abiotic factors occurring at different intensity levels and time scales. Deriving the time frame within which each factor has a causal influence is important ...
To elute or not to elute in immunocapture bottom-up LC–MS 
Levernæs, Maren Christin Stillesby; Nordlund, Marianne Sparby; Reubsaet, Leon; Halvorsen, Trine Grønhaug (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Immunocapture-based bottom-up LC–MS is a promising technique for the quantification of low abundant proteins. Magnetic immunocapture beads provide efficient enrichment from complex samples through the highly specific ...
Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation 
Feng, Yuan Zeng; Lund, Jenny; Li, Yuchuan; Knabenes, Irlin K; Bakke, Siril Skaret; Kase, Eili Tranheim; Lee, Yun K; Kimmel, Alan R; Thoresen, G. Hege; Rustan, Arild; Dalen, Knut Tomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Lipid droplet (LD) coating proteins are essential for the formation and stability of intracellular LDs. Plin2 is an abundant LD coating protein in skeletal muscle, but its importance for muscle function is unclear. We show ...
High and low concentration of 17?-estradiol protect cerebellar granule neurons in different time windows 
Sørvik, Irene Beate; Paulsen, Ragnhild Elisabeth (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
17α-estradiol is a hormonally inactive isomer of 17β-estradiol, but with similar potency as neuroprotector. However, we have previously reported that pretreatment with high concentration (10 μM) of both estrogens abolishes ...
  • «
  • 1
  • 2
  • 3
  • 4
  • »
 
Responsible for this website 
University of Oslo Library


Contact Us 
duo-hjelp@ub.uio.no


Privacy policy
 

 

For students / employeesSubmit master thesisAccess to restricted material

Browse

All of DUOCommunities & CollectionsBy Issue DateAuthorsTitlesThis CollectionBy Issue DateAuthorsTitles

For library staff

Login

Discover

Date Issued2020 - 2021 (65)2010 - 2019 (272)2002 - 2009 (11)Document Type
Tidsskriftartikkel (348)
AuthorNordeng, Hedvig Marie Egeland (37)Åsberg, Anders (30)Ystrøm, Eivind (28)Lupattelli, Angela (23)Hansen, Trond Vidar (18)... View MorePeer ReviewedPeer reviewed (332)
RSS Feeds
feedRSS 2.0
 
Responsible for this website 
University of Oslo Library


Contact Us 
duo-hjelp@ub.uio.no


Privacy policy