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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
The increasing need for personalized drug delivery requires developing systems with tailorable properties. The copolymer poly(vinyl alcohol-co-vinyl acetate) (PVA/PVAc) allows for adjusting the monomer ratio. This study ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background.
Trabecular bone score (TBS) is a new tool to assess trabecular bone microarchitecture based on standard dual-energy x-ray absorptiometry (DXA) of lumbar spine images. TBS may be important to assess bone ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Data on drug transfer into human breast milk are sparse. This study aimed to quantify concentrations of cetirizine and levocetirizine in breast milk and to estimate drug exposure to infants. Breastfeeding women ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objectives This study aims to assess risk factors for SARS-CoV-2 infection by combined design; first comparing positive cases to negative controls as determined by PCR testing and then comparing these two groups to an ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background and aims Statin-associated muscle symptoms (SAMS) is a prevalent cause of statin discontinuation. It is challenging and time-consuming for clinicians to assess whether symptoms are caused by the statin or not, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Adverse pregnancy outcomes (APO) may unmask or exacerbate a woman’s underlying risk for coronary heart disease (CHD). We estimated associations of maternal and paternal genetically predicted ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Daphne mezereum L., an important medicinal plant in Scandinavian folk medicine, was used to treat ailments such as diarrhea, swelling and stomach pain. A range of natural compounds have been isolated, but little attention ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
The secretion of extracellular vesicles (EVs) is a common process in Gram-negative bacteria and can be exploited for biotechnological applications. EVs pose a self-adjuvanting, non-replicative vaccine platform, where ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
This study investigates the influence of drug load and polymer molecular weight on the structure of tablets three-dimensionally (3D) printed from the binary mixture of prednisolone and hydroxypropyl methylcellulose (HPMC). ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Traditional Chinese Medicine (TCM) herbal products are increasingly used in Europe, but prevalent authentication methods have significant gaps in detection. In this study, three authentication methods were tested in a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Natural products obtained from marine organisms continue to be a rich source of novel structural architecture and of importance in drug discovery, medicine, and health. However, the success of such endeavors depends on the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Roots of Gentiana purpurea are known to have an intense bitter taste due to its high content of secoiridoids. In folk medicine roots have commonly been prepared as water decoctions, soaked in ethanol, or boiled with milk, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
This study explores the traditional knowledge of plants used by traditional health practitioners (THPs) in the treatment of symptoms or syndromes related to mental illnesses in the district of Bamako in Mali, along with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Introduction
The COVID-19 pandemic resulted in changes in prescription patterns and fillings for certain medications, but little is known about its impact on the dispensing of cardiovascular drugs.
Methods
Trends ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Shotgun metagenome sequencing data obtained from a host environment will usually be contaminated with sequences from the host organism. Host sequences should be removed before further analysis ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Imaging of in vitro neuronal differentiation and measurements of cell morphologies have led to novel insights into neuronal development. Live-cell imaging techniques and large datasets of images ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The objective of this study was to describe pregnancy- and birth-related experiences of postpartum women during the third wave of the COVID-19 pandemic and their association with mental health outcomes. An online questionnaire ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Ethnopharmacological relevance
Gentiana purpurea was one of the most important medicinal plants in Norway during the 18th and 19th centuries, and the roots were used against different types of gastrointestinal and airway ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Aim Children have largely been unaffected by severe COVID‐19 compared to adults, but data suggest that they may have experienced new conditions after developing the disease. We compared outcomes in children who ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Treatment-resistant schizophrenia affects approximately 30% of individuals with the disorder. Clozapine is the medication of choice in treatment-resistant schizophrenia, but optimizing administration and dose ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Child temperament traits and mothers' emotional symptoms relating to anxiety and depression may drive changes in one another, leading to their ‘co-development’ across time. Alternatively, links between mother ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Human liver tissue is composed of heterogeneous mixtures of different cell types and their cellular stoichiometry can provide information on hepatic physiology and disease progression. Deconvolution algorithms for the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Prenatal exposure to antiseizure medication (ASM) may lead to low plasma folate concentrations and is associated with impaired neurodevelopment.
Objectives
To examine whether maternal genetic liability ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective
To investigate the effect of an academic detailing intervention on the utilisation of type 2 diabetes medication among general practitioners.
Design
We developed an academic detailing campaign based on the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Lytic polysaccharide monooxygenases (LPMOs) catalyze oxidative cleavage of crystalline polysaccharides such as cellulose and are crucial for the conversion of plant biomass in Nature and in industrial applications. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: Exposure in utero to certain medications can disrupt processes of fetal development, including brain development, leading to a continuum of neurodevelopmental difficulties. Recognizing the deficiency of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: While adherence to cancer prevention recommendations is linked to lower risk of colorectal cancer (CRC), few have studied associations across the entire spectrum of colorectal carcinogenesis. Here, we studied ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Treatment resistant schizophrenia (TRS) is characterized by repeated treatment failure with antipsychotics. A recent genome-wide association study (GWAS) of TRS showed a polygenic architecture, but no significant loci were ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
In order to solubilize poorly soluble active pharmaceutical ingredients, various strategies have been implemented over the years, including the use of nanocarriers, such as cyclodextrins and liposomes. However, improving ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aims Atomoxetine is mainly metabolized by CYP2D6 while CYP2C19 plays a secondary role. It is known that patients carrying genotypes encoding decreased/absent CYP2D6 metabolism obtain higher atomoxetine concentrations and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Accumulating evidence has related the gut microbiota to colorectal cancer (CRC). Fusobacterium nucleatum has repeatedly been linked to colorectal tumorigenesis. The aim of this study was to investigate microbial ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
A scoping review from 2021 identified a lack of studies on the incidence, prevention and management of hypoglycaemia in home-dwelling older people with diabetes. The aim of this study was to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Although isotretinoin has anti-inflammatory and immunomodulatory properties, it can exacerbate atopic dermatitis. National estimates of the extent to which patients with atopic dermatitis are affected by severe acne and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Aim To investigate whether it is feasible to perform pharmacogenetic testing and implement the test results as part of medication reviews during hospitalization of multimorbid patients. Methods Patients with ≥2 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Several longitudinal studies have cast doubt on the aetiological overlap between child and adult attention-deficit hyperactivity disorder (ADHD). However, a lack of genetically sensitive data following children ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective
Based on the principle of the autonomy of the patient, shared decision-making (SDM) is the ideal approach in clinical encounters. In SDM, patients and healthcare professionals (HCPs) share knowledge and power ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Studies assessing associations between prenatal exposure to antidepressants, maternal depression, and offspring DNA methylation (DNAm) have been inconsistent. Here, we investigated whether prenatal exposure to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Pharmacoepigenetic studies are important to understand the mechanisms through which medications influence the developing fetus. For instance, we and others have reported associations between prenatal paracetamol exposure ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective: To describe the mental health of perinatal women in five European countries during the third pandemic wave and identify risk factors related to depressive and anxiety symptoms. Design: A cross-sectional, online ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Core genome multilocus sequence typing (cgMLST) employs a strategy where the set of orthologous genes common to all members of a group of organisms are used for phylogenetic analysis of the group members. The Bacillus ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Intravenous drugs are often co-administrated in the same intravenous catheter line due to which compatibility issues, such as complex precipitation processes in the catheter line, may occur. A well-known example that led ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
P-glycoprotein (P-gp) inhibitors, like zosuquidar, partly increase oral bioavailability of P-gp substrates, such as etoposide. Here, it was hypothesised that co-release of etoposide and zosuquidar from amorphous solid ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The methyl ester of resolvin D5n-3 DPA, a lipid mediator biosynthesized from the omega-3 fatty acid n-3 docosapentaenoic acid, was stereoselectively prepared in 8% yield over 12 steps (longest linear sequence). The key ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
In response to the growing ethical and environmental concerns associated with animal testing, numerous in vitro tools of varying complexity and biorelevance have been developed and adopted in pharmaceutical research and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background and Objective
Midazolam is the preferred clinical probe drug for assessing CYP3A activity. We have previously shown substantial intraindividual variability in midazolam absolute bioavailability and clearance ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Kidney transplant recipients (KTR) are at high risk for severe COVID-19 and have demonstrated poor response to vaccination, making it unclear whether successive vaccinations offer immunity and protection.
...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Aim To investigate whether mesna—sodium‐2‐mercaptoethane sulfonate) can reduce diet‐induced fat gain in mice, and to assess the safety of single ascending mesna doses in humans to find the dose associated with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aims Finger‐prick sampling has emerged as an attractive tool for therapeutic drug monitoring and associated diagnostics. We aimed to validate the clinical performance of using two volumetric devices (Capitainer® qDBS and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Clearance of neurotoxic brain proteins via cerebrospinal fluid (CSF) to blood has recently emerged to be crucial, and plasma biomarkers of neurodegeneration were newly introduced to predict neurological disease. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Oromucosal films and wafers are user-friendly solid dosage forms offering easy and convenient administration, as well as rapid or controlled drug delivery. The aim of this study was to develop prednisolone containing ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Kidney transplant recipients (KTRs) experienced reduced SARS-CoV-2 vaccine response and were at increased risk of severe COVID-19. It is unknown if level of vaccine induced anti-receptor binding domain IgG ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Background Reliable methods to detect and reduce medication nonadherence in solid organ‐transplanted (SOT) adolescents are warranted. We aimed to evaluate the feasibility of combining a medication‐manager application ...
The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho-physiological background
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract The roles of DGAT1 and DGAT2 in lipid metabolism and insulin responsiveness of human skeletal muscle were studied using cryosections and myotubes prepared from muscle biopsies from control, athlete, and impaired ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
ABSTRACT
Background
The aim of this study was to identify trends in total, deceased donor (DD) and living donor (LD) kidney transplantation (KT) rates in European countries.
...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background.
Mycophenolate mofetil (MMF) is an immunosuppressive prodrug often used to prevent allograft rejection following solid organ transplantation. After oral administration, MMF is rapidly hydrolyzed to the active ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
In combination with Bayesian estimates based on a population pharmacokinetic model, limited sampling strategies (LSS) may reduce the number of samples required for individual pharmacokinetic parameter estimations. Such ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Acute sleep deprivation has been shown to affect cerebrospinal fluid and plasma concentrations of biomarkers associated with neurodegeneration, though the mechanistic underpinnings remain unknown. This ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objectives Treatment of respiratory infections with non-typeable Haemophilus influenzae (NTHi) in COPD patients is complicated by biofilm formation, protecting the bacteria against the hosts’ immune response and antibiotics. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Few antibiotics have entered the market in recent years despite the need for new treatment options. Some of the challenges of bringing new antibiotics to market are linked to the marketing ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Baricitinib has shown efficacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifically on severe/critical COVID, including vaccinated participants.
Methods
Bari-SolidAct ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Knowledge about the effectiveness of antidepressants in pregnancy is limited. We aimed to evaluate the association of antidepressant continuation in pregnancy and adherence with the risk of antenatal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Maternal personality is a possible confounder on the association between prenatal medication exposure and long-term developmental outcomes in offspring, but it is often unmeasured. This study aimed to (i) estimate the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Purpose
To examine the association between endometriosis and adverse pregnancy and perinatal outcomes (preeclampsia, placenta previa, and preterm birth).
Methods
A ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
BACKGROUND: Persons with severe intellectual disability (ID) may be non-verbal and unable to communicate pain or distress. Consequently, painful conditions may go undetected, and non-verbal persons with ID may not receive ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
The roots of Salvia miltiorrhiza have been used in Traditional Chinese Medicine for thousands of years. However, tons of aerial parts of this plant are usually discarded in the production of roots preparation. To make ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Introduction Fluvoxamine is widely used to treat depression during pregnancy and lactation. However, limited data are available on its transfer to the fetus or in human milk. This case series provides additional information ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The interplay between skeletal muscle and bone is primarily mechanical; however, biochemical crosstalk by secreted mediators has recently gained increased attention. The aim of this study was to investigate metabolic effects ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Importance Although selective serotonin reuptake inhibitors (SSRIs) are recommended for postnatal depression treatment, there is a lack of evidence regarding long-term maternal and child outcomes following postnatal SSRI ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Introduction: Skeletal muscle is a major contributor to whole-body energy homeostasis and the utilization of fatty acids and glucose. At present, 2D cell models have been the most used cellular models to study skeletal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Prenatal paracetamol exposure has been associated with neurodevelopmental outcomes in childhood. Pharmacoepigenetic studies show differences in cord blood DNA methylation between unexposed and paracetamol-exposed neonates, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aims To develop a disease risk score for COVID-19-related hospitalization and mortality in Sweden and externally validate it in Norway. Method We employed linked data from the national health registries of Sweden and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Perinatal depression is the most undertreated clinical condition during the perinatal period. Knowledge about women's decision-making in seeking and receiving treatment is scarce.
Aims
To investigate and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
With COVID-19 vaccination hesitancy at around 50% in the obstetric population, it is critical to identify which women should be addressed and how. Our study aimed to assess COVID-19 vaccination willingness among pregnant ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Introduction
Individual case reports are the main asset in pharmacovigilance signal management. Signal validation is the first stage after signal detection and aims to determine if there is sufficient evidence to justify ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Persistent symptoms following the acute phase of COVID-19 present a major burden to both the affected and the wider community. We conducted a cohort study including over 856,840 first COVID-19 cases, 72,422 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
This study aims to investigate decisional conflict and elucidate challenges in decision-making among perinatal women using or considering using antidepressant (AD) during pregnancy. A sequential, mixed-methods study was ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Immunotherapeutic interventions that block drug effects by binding drug molecules to specific antibodies in the bloodstream have shown promising effects in animal studies. For heroin, which effects are mainly ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Adipose tissue is one of the main regulative sites for energy metabolism. Excess lipid storage and expansion of white adipose tissue (WAT) is the primary contributor to obesity, a strong predisposing factor for development ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: Studies on disease-related obstructions experienced in everyday life of younger people with dementia (YOD ≤ 65 years) and their families are encouraged.
Aim: To explore how the family carers experience six ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Transient potential (TRP) ion channels expressed in primary sensory neurons act as the initial detectors of environmental cold and heat, information which controls muscle energy expenditure. We hypothesize that non-neuronal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aims To investigate the effect of aging, sex and cytochrome P450 (CYP) genotypes on the exposure of quetiapine (QUE) and the pharmacologically active metabolite N ‐desalkylquetiapine (NDQ). Methods Patients with serum ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Resolvin E4 (RvE4) belongs to the resolvin family of specialized pro-resolving mediators (SPMs). The resolvins are endogenously formed mediators with both potent pro-resolving and anti-inflammatory biological activities ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
In response to the World Health Organization's (WHO) call to develop alternative antibacterial methods, we investigate endogenous compounds and biopolymers. Lumichrome (LC) is an endogenous, lipophilic degradation product ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Introduction Psychotic‐like experiences (PLE) have been associated with the subsequent emergence of psychotic disorders as well as several other domains of psychopathology. In this twin study, we estimated the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Parenteral (intravenous) nutrition is lifesaving for patients with intestinal failure, but long-term use of parenteral nutrition often leads to liver disease. SEFA-6179 is a synthetic medium-chain fatty acid ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective
Non-shivering thermogenesis (NST) mediated by uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) can be activated via the adrenergic system in response to cold or diet, contributing to both thermal and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Antidepressants are used to treat depression and some anxiety disorders, including use in pregnant patients. The pharmacological actions of these drugs generally determine the uptake and metabolism of a series of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Development of the dorsal aorta is a key step in the establishment of the adult blood-forming system, since hematopoietic stem and progenitor cells (HSPCs) arise from ventral aortic endothelium in all vertebrate animals ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
Human milk is the most appropriate form of nutrition for infants while taking medication during the postpartum period is common. Discontinuation of breastfeeding is sometimes wrongly recommended for fear of adverse effects ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Background
Periconceptional use of oral contraceptives (OCs) has been reported to increase risks of pregnancy complications and adverse birth outcomes, but risks are suggested to ...
Generic Liquid Membranes for Electromembrane Extraction of Bases with Low or Moderate Hydrophilicity
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
For the first time, this paper introduces the idea of generic extraction conditions in electromembrane extraction (EME), where the selection of the liquid membrane is based on the charge (z) and hydrophobicity (log P) of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Stroke is the main cause of acquired disability in adults. Exercise reduces the risk for stroke and protects against functional loss after stroke. An exercise-induced reduction in key risk factors probably contributes to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aim To perform a systematic review on the use of Artificial Intelligence (AI) techniques for predicting COVID-19 hospitalization and mortality using primary and secondary data sources. Study eligibility criteria Cohort, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Natural deep eutectic solvents (NADES) are a class of liquids with promising properties as components in pharmaceutical formulations, such as a low toxicity profile, biodegradability and versatility. Recently, their potential ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Separation and quantification of amphetamine enantiomers are commonly used to distinguish between consumption of prescription amphetamine (mostly S ‐amphetamine) and illicit forms of the drug (racemate). In this ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The use and/or misuse of opioids by pregnant women would expose the fetuses to these drugs during critical stages of development with serious effects for the newborn, like the neonatal abstinence syndrome (NAS). We have ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract The use of oral fluid as sample matrix has gained significance in the analysis of drugs of abuse due to its non-invasive nature. In this study, the 13 opioids morphine, oxycodone, codeine, O-desmethyl tramadol, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract In 2017 integrated sampling and sample preparation for simplified liquid chromatography‐mass spectrometry analysis of proteins from dried blood spots were introduced. The concept, called smart samplers or smart ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
This perspective explores the feasibility of smart sampling with dried blood spots for the determination of proteins and peptides from human biomatrices using liquid chromatography coupled to mass spectrometry for clinical ...