Now showing items 1-4 of 4

  • Lund, Jenny; Ouwens, DM; Wettergreen, Marianne; Bakke, Siril Skaret; Thoresen, G. Hege; Aas, Vigdis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Previous studies have shown that chronic hyperglycemia impairs glucose and fatty acid oxidation in cultured human myotubes. To further study the hyperglycemia-induced suppression of oxidation, lactate oxidation, mitochondrial ...
  • Bakke, Siril Skaret; Feng, Yuan Zeng; Nikolic, Natasa; Kase, Eili Tranheim; Moro, Cedric; Stensrud, Camilla; Damlien, Lisbeth; Ludahl, Marianne Odnakk; Sandbu, Rune; Solheim, Brita Marie; Rustan, Arild; Hjelmesæth, Jøran; Thoresen, G. Hege; Aas, Vigdis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    About 80% of patients with type 2 diabetes are classified as overweight. However, only about 1/3 of severely obese subjects have type 2 diabetes. This indicates that several severely obese individuals may possess certain ...
  • Aas, Vigdis; Thoresen, G. Hege; Rustan, Arild; Lund, Jenny (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Primary human myotubes represent an alternative system to intact skeletal muscle for the study of human diseases related to changes in muscle energy metabolism. This work aimed to study if fatty acid and glucose ...
  • Lund, Jenny; Aas, Vigdis; Tingstad, Ragna Husby; Van Hees, Alfons; Nikolic, Natasa (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular ...