This project is designed to provide mental health professionals, educators and others, with current information on how horses can be used in therapy for rare congenital disorders. This information is used to define the theoretical basis of my thesis and to justify the hypothesis. Purpose: Compile a literature review to further knowledge on the main characteristics of the syndromes of the two children in this study, diagnosed by rare genetic disorders, such as Robertsonian translocation 45, XY, t(13q, 14q) and unbalanced translocation (partial trisomy 11 and monosomy 4). Describe and explore holistic hippotherapy in children with these particular characteristics. Method: The study focused on several exploratory case studies describing results of individual intervention with hippotherapy. Using a non random proposal sample of 2 children diagnosed with rare congenital disorders (atypical syndromes), aged 2-5 years. As a holistic study, the information was completed with the experiences of parents and psychologists (8 informants). Data were collected in face-to-face interviews with the mothers and psychologists, observation of the children using observation development scales (Battelle and Portage Guide to Early Intervention and Observation Assessment Scale) and text analysis (child’s medical history and literature review). This will be accomplished with pre-test measurements, implementing the program and replicating the same tests several times.Results: Both children have a positive development in a holistic way related with the therapeutic programme.Conclusion: This study confirms the findings of other similar studies on the advantages of the use of hippotherapy in children with similar characteristics. The extensive information collected in this study offers the possibility of future replication with specific cases in controlled studies.