Obesity and type 2 diabetes (T2D) are associated with reduced metabolic flexibility and the development of these conditions are positively associated with dietary saturated fatty acids (e.g. palmitic acid) and negatively ...

Use of medications, including psychotropics, is common during pregnancy. Indeed, many women might be in need of pharmacotherapy during pregnancy in order to ensure maternalfetal health. However, discordant findings or lack ...

Sambucus nigra L. or black elder has a long history of use in traditional European medicine for treatment of inflammations, infections, diabetes and for boosting the immune system. The aim of this thesis was to investigate ...

Glutamate is the major excitatory neurotransmitter in the mammalian CNS. Excitotoxicity refers to the ability of glutamate to destroy neurons, and this pathological condition may occur e.g. during stroke. In this thesis, ...

The prevalence of type 2 diabetes (T2D) has increased worldwide during the last decades. Obesity and accumulation of lipids in skeletal muscles are strongly associated with T2D. Much focus has been on the possibility of ...

Mobile genetic elements have had, and still have an impact on the evolution of the genomes providing means for adaptation and structural organization. These elements are one of the major driving forces for the general ...

Non-living antigens are often poorly immunogenic and require addition of adjuvants to elicit protective immunity. Due to the immunostimulatory potential of Toll-like receptor (TLR) ligands, they are explored as vaccine ...

The work presented in this thesis employed knowledge in medicinal chemistry to discover new compounds aiming to reduce resistance in infections caused by virulent Gram-negative bacteria, resistant to antibiotics. The general ...

The main purpose of this thesis was to evaluate the potential of pectins from the Malian medicinal tree Cola cordifolia used in the treatment of gastric ulcer and wounds. This thesis is a small contribution to the ultimate ...