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dc.date.accessioned2013-03-12T12:49:05Z
dc.date.available2013-03-12T12:49:05Z
dc.date.issued2001en_US
dc.date.submitted2004-08-20en_US
dc.identifier.citationToungoussova, Olga. Determination of risk factors for the development of tuberculosis with drug-resistant strains of Mycobacterium tuberculosis in the Arkhangelsk oblast, Russia. Masteroppgave, University of Oslo, 2001en_US
dc.identifier.urihttp://hdl.handle.net/10852/30090
dc.description.abstractDESIGN: Strains isolated from 119 patients with pulmonary tuberculosis were studied by the BACTEC method. Medical records of the patients were reviewed, retrospectively, to identify factors associated with drug resistance. RESULTS: Sixty-seven strains (56.3%) were resistant to at least one antituberculosis drug. Thirty of the 119 strains (25.2%) were multi-drug resistant. All strains resistant to rifampicin were multi-drug resistant. Multidrug resistance was four times more common among previously treated patients than among new patients. The highest rates of drug resistance were observed for streptomycin and isoniazid. 40.4% and 66.7% of strains collected from new and previously treated patients were resistant to streptomycin, respectively. 37.1% and 73.3% of strains collected from new and previously treated patients were resistant to isoniazid, respectively. A history of previous or interrupted treatment for tuberculosis and being female were significantly associated with resistance to at least one anti-tuberculosis drug and multidrug resistance. CONCLUSION: Drug-resistant tuberculosis is an important problem in the Arkhangelsk oblast, Russia. The spread of drug-resistant strains of M. tuberculosis is attributed to several risk factors. A history of previous or interrupted treatment for tuberculosis and being female are significantly associated with resistance to at least one anti-tuberculosis drug and multidrug resistance. Employment in the health sector of Arkhangelsk was significantly associated with the development of drug resistance.nor
dc.language.isoengen_US
dc.titleDetermination of risk factors for the development of tuberculosis with drug-resistant strains of Mycobacterium tuberculosis in the Arkhangelsk oblast, Russiaen_US
dc.typeMaster thesisen_US
dc.date.updated2006-12-15en_US
dc.creator.authorToungoussova, Olgaen_US
dc.subject.nsiVDP::751en_US
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft.au=Toungoussova, Olga&rft.title=Determination of risk factors for the development of tuberculosis with drug-resistant strains of Mycobacterium tuberculosis in the Arkhangelsk oblast, Russia&rft.inst=University of Oslo&rft.date=2001&rft.degree=Masteroppgaveen_US
dc.identifier.urnURN:NBN:no-9599en_US
dc.type.documentMasteroppgaveen_US
dc.identifier.duo20659en_US
dc.contributor.supervisorGunnar Bjune, Dominique A. Caugant, Per Sandven, Andrey Mariandysheven_US
dc.identifier.bibsys041699831en_US
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/30090/1/toungoussova.pdf


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