Background Pathogenesis of inflammatory diseases can be tracked by studying the causality relationships among the factors contributing to its development. We could, for instance, hypothesize on the connections ...

Background Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) ...

Background The consequences of lifestyle-related disease represent a major burden for the individual as well as for society at large. Individual preventive health checks to the general population have been ...

Background Mammography screening is used to detect breast cancer at an early treatable stage, reducing breast cancer mortality. Traditionally, breast cancer has been seen as a disease with only progressive ...

Background The ballan wrasse (Labrus bergylta) belongs to a large teleost family containing more than 600 species showing several unique evolutionary traits such as lack of stomach and hermaphroditism. ...

The rapidly increasing pervasiveness and integration of computers in human society calls for a broad discipline under which this development can be studied. We argue that to design and use technology one needs to develop ...

Background The genetic mechanisms for families who meet the clinical criteria for Lynch syndrome (LS) but do not carry pathogenic variants in the mismatch repair (MMR) genes are still undetermined. We aimed ...

Background Although chemo-immunotherapy has led to an improved overall survival for most B-cell lymphoma types, relapsed and refractory disease remains a challenge. The malaria drug artesunate has previously ...

Background The current versions of reference genome assemblies still contain gaps represented by stretches of Ns. Since high throughput sequencing reads cannot be mapped to those gap regions, the regions ...

Background In laparoscopic surgery, image quality can be severely degraded by surgical smoke, which not only introduces errors for the image processing algorithms (used in image guided surgery), but also ...

Background Increased availability of genome assemblies for non-model organisms has resulted in invaluable biological and genomic insight into numerous vertebrates, including teleosts. Sequencing of the ...

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The challenge addressed in this paper consists in offloading packet-based pacing to a hardware Network Interface Card, while retaining the flexibility of software timers. In this direction, we propose, design, implement, ...

RoboJam is a machine-learning system for generating music that assists users of a touchscreen music app by performing responses to their short improvisations. This system uses a recurrent artificial neural network to ...

Identity today has become a complex issue. An average user of the Internet has accounts on several services, and several traces of use are gathered by large companies. However, the same companies are using Artificial ...

Background In kindreds carrying path_BRCA1/2 variants, some women in these families will develop cancer despite testing negative for the family’s pathogenic variant. These families may have additional ...

Amidst the rapid development of the fifth generation (5G) networks, Internet of Things (IoT) is considered as one of the most important part of 5G next generation networks as it can support massive object communications. ...

We use dependency triples automatically extracted from a Web-scale corpus to perform unsupervised semantic frame induction. We cast the frame induction problem as a triclustering problem that is a generalization of clustering ...

Recent years have witnessed a surge of publications aimed at tracing temporal changes in lexical semantics using distributional methods, particularly prediction-based word embedding models. However, this vein of research ...

This paper explores the role of design and use of digital feedback mechanisms in domestic autonomous devices. We explore this in relation to elderly’s trust towards robots. Specifically, the paper reflects on a case study ...

Obstructive Sleep Apnea (OSA) is a common, but severely under- diagnosed sleep disorder characterized by recurring periods of shallow or paused breathing during sleep. It is our long-term goal to allow people to perform ...

Nested virtualization enables a virtual machine, which is a software layer representing an execution environment, to be placed inside another virtual machine. Nested virtual machines form a location hierarchy where virtual ...

Evaluation of Distributed Complex Event Processing (CEP) systems is a rather challenging task. To simplify this task, we developed the open simulation framework for Distributed CEP, called DCEP-Sim. The goal of this tutorial ...

Concerns have been raised regarding the economical viability for each operator to have a full regional 5G coverage. A possible solution is to have traffic offloaded to competitors. In this work we present a new scheme for ...

This paper gives an example-driven introduction to modelling and analyzing virtualized systems in, e.g., cloud computing, using virtually timed ambients, a process algebra developed to study timing aspects of resource ...

This paper presents a novel CMOS-based system-onchip with a 78 × 56 ion-sensitive field-effect transistor array using in-pixel quantization and compensation of sensor nonidealities. The pixel integrates sensing circuitry ...

Image guided surgery systems aim to support surgeons by providing reliable pre-operative and intra-operative imaging of the patient combined with the corresponding tracked instrument location. The image guidance is based ...

Secure software development represents a fundamental part of ‘security by design’ which in turn is a prerequisite for ‘privacy by design’ in the terminology of GDPR (General Data Protection Regulation). To follow and adhere ...

In this work, we study different types of uncertainty in subjective opinions based on the internal belief mass distribution and the base rate distribution. Subjective opinions which are used as arguments in subjective logic ...

The aryl hydrocarbon receptor (AHR) mediates the toxic effects of dioxin (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin; TCDD), which includes thymic atrophy, steatohepatitis, and a lethal wasting syndrome in laboratory rodents. ...

In ontology-based data access (OBDA), databases are connected to an ontology via mappings from queries over the database to queries over the ontology. In this paper, we define an ASP-based semantics for mappings from ...

Colorectal cancer (CRC) is one of the most common cancers in Latin America and the Caribbean, with the highest rates reported for Uruguay, Brazil and Argentina. We provide a global snapshot of the CRC patterns, how screening ...

In recent years, there has been increased attention on the possible impact of future robotics and AI systems. Prominent thinkers have publicly warned about the risk of a dystopian future when the complexity of these systems ...

Background: New data on extracranial carotid atherosclerosis are needed, as improved ultrasound techniques may detect more atherosclerosis, the definition of plaque has changed over the years, and better cardiovascular ...

The aim of this paper is to elucidate the implications of quantum computing in present cryptography and to introduce the reader to basic post-quantum algorithms. In particular the reader can delve into the following subjects: ...

Energy usage in LTE base stations are driven by spectral efficiency and traffic. To predict the energy usage these parameters must be forecasted. In this work we analyse hourly measurements collected from more than 12000 ...

Background: Molecular indicators of colorectal cancer prognosis have been assessed in several studies, but most analyses have been restricted to a handful of markers. We aimed to identify prognostic biomarkers for colorectal ...

The elderly in the future will use smart house technology, sensors, and robots to stay at home longer. Privacy at home for these elderly is important. In this exploratory paper, we examine different understandings of privacy ...

This paper presents the Norwegian Review Corpus (NoReC), created for training and evaluating models for document-level sentiment analysis. The full-text reviews have been collected from major Norwegian news sources and ...

We present ctrlTCP, a method to combine the congestion controls of multiple TCP connections. In contrast to the previous methods such as the Congestion Manager, ctrlTCP can couple all TCP flows that leave one sender, ...

Obstructive sleep apnea (OSA) is a common but severely under-diagnosed sleep disorder that affects the natural breathing cycle during sleep with the periods of reduced respiration or no airflow at all. It is our long-term ...

In this paper, we empirically evaluate the utility of transfer and multi-task learning on a challenging semantic classification task: semantic interpretation of noun--noun compounds. Through a comprehensive series of ...

Knowledge Graphs have recently gained a lot of attention and have been successfully applied in both academia and industry. Since KGs may be very large: they may contain millions of entities and triples relating them to ...

In this paper we investigate how data openness can be made possible in communal settings. We adopt a utility perspective that foregrounds the use value of data, conceptualizing them as “goods.” On the basis of this ...

With this contribution we present some recent developments made to Rucio, the data management system of the High-Energy Physics Experiment ATLAS. Already managing 300 Petabytes of both official and user data, Rucio has ...

Privacy is often applied as an abstract concept in law and regulations. In everyday life, negotiating what information to share with whom, where, and at what times, and in what situations may be a challenge at home and in ...

The elderly in the future will use smart house technology, sensors, and robots to stay at home longer. Privacy at home for these elderly is important. In this exploratory paper, we examine different understandings of privacy ...

A robot moving in the home is a new experience for most people. Classifying the different ways that humans and robots move together can help in designing interactions. In this paper, we first put robots’ movements into two ...

The paper reports our participation in the shared task on word sense induction and disambiguation for the Russian language (RUSSE’2018). Our team was ranked 2nd for the wiki-wiki dataset (containing mostly homonyms) and ...

One of the primary characteristics of robots is the ability to move autonomously in the same space as humans. In what ways does movement influence the interaction between humans and robot? In this paper, we examine how ...

Ontologies are a powerful mechanism to structure domains of interest. They have successfully been applied in medical domain, industry and other important areas. Despite the simplicity of ontological vocabularies that consist ...

KRAS mutation is a well‐known marker for poor response to targeted treatment and patient prognosis in microsatellite stable (MSS) colorectal cancer (CRC). However, variation in clinical outcomes among patients wild‐type ...

Individually personalized computational models of heart mechanics can be used to estimate important physiological and clinically‐relevant quantities that are difficult, if not impossible, to directly measure in the beating ...

By offering high sequencing speed and ultra-high-throughput at a low price, Illumina next-generation sequencing platforms have been widely adopted in recent years. However, an experiment with multiplexed library could be ...

We examine how robot movement can help human-robot interaction in the context of a robot helping people over 60-years old at home. Many people are not familiar with a robot moving in their home. We present four movement ...

Today, many users of multimedia applications are surrounded by a changing set of multimedia-capable devices. However, users can move their running multimedia applications only to a pre-defined set of devices. Application ...

As the application domains of sampling-based motion planning grow, more complicated planning problems arise that challenge the functionality of these planners. One of the main challenges in the implementation of a ...

Background: Digital innovations have evolved over the last 15 years to support health activities, and their introduction in low- and middle-income countries has shown the potential to catalyze gains in health systems and ...

Motivation: Many high-throughput methods produce sets of genomic regions as one of their main outputs. Scientists often use genomic colocalization analysis to interpret such region sets, for example to identify interesting ...

In this work we present the Talk of Norway (ToN) data set, a collection of Norwegian Parliament speeches from 1998 to 2016. Every speech is richly annotated with metadata harvested from different sources, and augmented ...

Computer networks research has been notoriously bad at reproducibility – a key aspect of making research results credible and convincing. This has been attributed to a lack of incentive for researchers to share the data ...

Objective: A major goal in systems neuroscience is to determine the causal relationship between neural activity and behavior. To this end, methods that combine monitoring neural activity, behavioral tracking, and targeted ...

Targeted therapy for patients with HER2‐positive (HER2+) breast cancer has improved overall survival, but many patients still suffer relapse and death from the disease. Intratumor heterogeneity of both estrogen receptor ...

Driven by the evolutionary development of automobile industry and cellular technologies, dependable vehicular connectivity has become essential to realize future intelligent transportation systems (ITS). In this paper, we ...

It is essential to focus on universal design in agile software development to ensure that the software developed is usable by as many people as possible. This work studies how members of agile teams regard universal design, ...

This paper studies the secure transmission rate issue between sensors and the remote controller to defend the jamming and eavesdropping attacks in green cyber-physical transportation systems. In this system, the traffic ...

The pathophysiology of atrial fibrillation (AF) is broad, with components related to the unique and diverse cellular electrophysiology of atrial myocytes, structural complexity, and heterogeneity of atrial tissue, and ...

For robots to handle the numerous factors that can afect them in the real world, they must adapt to changes and unexpected events. Evolutionary robotics tries to solve some of these issues by automatically optimizing a ...

Recent strategic design and management discourse has identified gaps in the current framing of design for organisations, specifically highlighting a lack of discussions related to emergent design cultures and calling for ...

One of the major obstacles in automatic polyp detection during colonoscopy is the lack of labeled polyp training images. In this paper, we propose a framework of conditional adversarial networks to increase the number of ...

Malicious attacks in the power system can eventually result in a large-scale cascade failure if not rectified in a timely manner. These attacks, which are traditionally classified into physical and cyber attacks, can be ...

—Communication technology improvements have inspired the idea of connecting almost every things to the Internet: from home appliances, medical devices, and cars, to large infrastructures. A unified and secure network of ...

Communication between two Internet hosts using parallel connections may result in unwanted interference between the connections. In this dissertation, we propose a sender-side solution to address this problem by letting ...

A significant problem of using deep learning techniques is the limited amount of data available for training. There are some datasets available for the popular problems like item recognition and classification or self-driving ...

Functional genomics assays produce sets of genomic regions as one of their main outputs. To biologically interpret such region-sets, researchers often use colocalization analysis, where the statistical significance of ...

With the advent of Internet of things (IoT) and cloud computing technologies, we are in the era of automation, device-to-device (D2D) and machine-to-machine (M2M) communications. Automated vehicles have recently gained a ...

Task admission is critical to delay-sensitive applications in mobile edge computing, but is technically challenging due to its combinatorial mixed nature and consequently limited scalability. We propose an asymptotically ...

Background Chromatin organisation affects gene expression and regional mutation frequencies and contributes to carcinogenesis. Aberrant organisation of DNA has been correlated with cancer prognosis in analyses of the ...

In a recent study we have encountered an unexpected result regarding the evolutionary exploration of robot morphology spaces. Specifically, we found that an algorithm driven by selection based on morphological novelty ...

While it is generally accepted that patient centred care should be the guiding principle for the delivery of health services, it is not yet clear how this should be digitalised. What is clear, however, is that the current ...

As a promising branch of Internet of Things, Internet of Vehicles (IoV) is envisioned to serve as an essential data sensing and processing platform for intelligent transportation systems. In this paper, we aim to address ...

Genomic alterations occurring during melanoma progression and the resulting genomic heterogeneity between metastatic deposits remain incompletely understood. Analyzing 86 metastatic melanoma deposits from 53 patients with ...

To enable elderly people to live independently in their homes, the government aims to de-institutionalize elderly care services by upscaling home care services and care housing and downscaling long-term stays at nursing ...

Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is the most popular assay to identify genomic regions, called ChIP-seq peaks, that are bound in vivo by transcription factors (TFs). These regions are derived ...

This paper focuses on the process of translating insights from a Computer Supported Cooperative Work (CSCW)-based study, conducted on a vessel at sea, into a model that can assist systems developers working with simulators, ...

Background: Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) and inhibits its ...

The HyVar project (www.hyvar-project.eu/) proposes a development framework for continuous and individualized evolution of distributed software applications running on remote devices in heterogeneous environments, focusing ...

In this paper, we study how to efficiently integrate multiple relational databases using an ontology-based approach. In ontology-based data integration (OBDI) an ontology provides a coherent view of multiple databases, and ...

Background Most patients with path_MMR gene variants (Lynch syndrome (LS)) now survive both their first and subsequent cancers, resulting in a growing number of older patients with LS for whom limited information exists ...

Summary Individual tumor genomes pose a major challenge for clinical interpretation due to their unique sets of acquired mutations. There is a general scarcity of tools that can (i) systematically interrogate cancer ...

Energy hub integrates various energy conversion and storage technologies, which can yield complementarity among multiple energy and provide consumers with stable energy services, such as electricity, heating, and cooling. ...

By analogy with Internet of things, Internet of vehicles (IoV) that enables ubiquitous information exchange and content sharing among vehicles with little or no human intervention is a key enabler for the intelligent ...

This paper presents a case of co-design for people with rheumatic disorder to support the argument of opening up the design space to include interaction opportunities found in the physical world. The position argued for ...

Sample pooling enabled by dedicated indexes is a common strategy for cost-effective and robust high-throughput sequencing. Index misassignment leading to mutual contamination between pooled samples has however been described ...

Internet of Things (IoT) provides ubiquitous intelligence and pervasive interconnections to diverse physical objects. The overall network performance of existing IoT is restricted by limited network lifetime. Hence, energy ...

Industrial Internet of unmanned aerial vehicles (IIoUAVs) that enable autonomous inspection and measurement of anything anytime anywhere have become an essential component of the future industrial Internet of things (IIoT) ...

In industrial Internet of things (IIoT), peer-to-peer (P2P) energy trading ubiquitously takes place in various scenarios, e.g., microgrids, energy harvesting networks, and vehicle-to-grid networks. However, there are common ...

Walter is a distributed partially replicated data store providing Parallel Snapshot Isolation (PSI), an important consistency property that offers attractive performance while ensuring adequate guarantees for certain kinds ...

When a person is concurrently interacting with different systems, the amount of cognitive resources required (cognitive load) could be too high and might prevent some tasks from being completed. When such human multitasking ...