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Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify ...
The longitudinal transcriptional response to neoadjuvant chemotherapy with and without bevacizumab in breast cancer
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Purpose: Chemotherapy-induced alterations to gene expression are due to transcriptional reprogramming of tumor cells or subclonal adaptations to treatment. The effect on whole-transcriptome mRNA expression was investigated ...