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dc.date.accessioned2013-03-12T12:40:29Z
dc.date.available2013-03-12T12:40:29Z
dc.date.issued2010en_US
dc.date.submitted2010-11-05en_US
dc.identifier.citationKaldestad, Sarah Kristine. Prion Diseases: Fatal and greatly feared. . Prosjektoppgave, University of Oslo, 2010en_US
dc.identifier.urihttp://hdl.handle.net/10852/29549
dc.description.abstractPrion diseases (or transmissible spongiform encephalopathies) are rare, infectious neurodegenerative disorders caused by the accumulation of aberrant prion proteins in the brain. TSEs can affect both animals and humans and can be transmitted with varying degrees of efficiency between species. Prion disease can be sporadic, genetic, or acquired. Testing in humans is not feasible, yet, alarmingly, vCJD has been shown to transmit through blood transfusions. Other patients have been iatrogenically infected from surgical instruments that were contaminated with prions. Prions are extremely difficult to inactivate and standard disinfection methods for surgical equipment are inadequate. There are at present time no effective treatments for TSEs in humans or in animals. The incubation time is generally long, but death usually occurs within months after the onset of clinical disease. The aim of this paper is to present an overview of the prion diseases, including medical, historical, legal, and economical perspectives.eng
dc.language.isoengen_US
dc.titlePrion Diseases: Fatal and greatly feared. : A review of current knowledge, two and a half centuries after the 1st description of scrapie.en_US
dc.typeMaster thesisen_US
dc.date.updated2011-05-10en_US
dc.creator.authorKaldestad, Sarah Kristineen_US
dc.subject.nsiVDP::752en_US
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft.au=Kaldestad, Sarah Kristine&rft.title=Prion Diseases: Fatal and greatly feared. &rft.inst=University of Oslo&rft.date=2010&rft.degree=Prosjektoppgaveen_US
dc.identifier.urnURN:NBN:no-26400en_US
dc.type.documentProsjektoppgaveen_US
dc.identifier.duo107255en_US
dc.contributor.supervisorProfessor Jan Mæhlenen_US
dc.identifier.bibsys112601197en_US
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/29549/1/Prosjekt-kaldestad.pdf


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