Background: In a study from Norway from 2003, the survival rate after admission to ICU following successful resuscitation after out-of-hospital cardiac arrest (OHCA) was 56% in Stavanger and only 34% in Oslo. Therefore, a new treatment protocol was introduced at Ullevaal Universitetssykehus (UUS) including therapeutic hypothermia and a more aggressive treatment of the underlying cause. The aim of this study was to assess the results and evaluate the treatment after the introduction of this new protocol.Material and methods: The journals of all patients admitted to the emergency department at UUS after OHCA in the period of 01.09.03 – 01.12.04 were examined retrospectively. The main focus was overall results, but the general implementation and especially performance of the therapeutic hypothermia including side effects were of great interest. Results: A total of 92 patients were brought to the emergency room at UUS, and 25 of these were declared dead in the emergency room and one patient died during the PCI-procedure. A total of 66 patients were admitted to different ICUs, and 34 of these (52%) were discharged alive. Of those admitted to ICU, 51 patients (77%) had a cardiac cause and 32 (63%) were discharged alive. Altogether 41 (61%) patients were treated with therapeutic hypothermia, and 29 (%) patients received PCI-treatment. Of all discharged patients 97 % had a CPC-score of one or two. Conclusion: Survival and cerebral performance after successful resuscitation after OHCA is considerably improved after the establishment of a standardised treatment protocol focusing on vital organ perfusion.