Self-poisonings in Oslo: Epidemiology, substance use, psychosocial factors and prognosis
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AbstractSelf-poisonings are mainly due to suicidal behaviour or accidental poisonings as a result of substance use disorders, and both groups exhibit aspects of self-destructive behaviour. Most studies focus on subgroups, mainly based on evaluated intention. Knowledge is therefore fragmented with respect to toxic agents, extent, common features and prognosis. The aim of this thesis was to study patients with self-poisonings who have been treated at the Emergency Department as a single risk group.
In a one-year cross-sectional multi-center study of self-poisonings treated at Emergency Departments in Oslo in 2003-04, epidemiology, short-term prognosis and psychosocial characteristics of self-poisonings were explored. A single-center study from 2001 compared the clinical and the laboratory identification of drugs of abuse in self-poisonings. In order to study long-term prognosis, a cohort of all self-poisonings treated at Medical Departments in Oslo in 1980 was followed prospectively during 20 years, and overall mortality rate as well as cause-specific mortality rates were compared with rates for the general population. Suicide risk was emphazised. Opioid addicts were studied as a high risk group.
LIST OF PAPERS
I. Hovda KE, Bjornaas MA, Skog K, Opdahl A, Drottning P, Ekeberg O, and Jacobsen D. Acute poisonings treated in an Oslo hospital: A one-year prospective study (I): Pattern of poisoning. Clin Toxicol 2008; 46:35-41
II. Bjornaas MA, Hovda KE, Mikalsen H, Andrew E, Rudberg, N, Ekeberg O, Jacobsen D. Clinical versus laboratory identification of drugs of abuse in patients admitted for acute poisoning. Clin Toxicol 2006; 44: 127-134
III. Heyerdahl F, Bjornas MA, Hovda KE, Skog K, Opdahl A, Wium C, Ekeberg O, and Jacobsen D. Acute poisonings treated in an Oslo hospital: A one-year prospective study (II). Clinical outcome. Clin Toxicol 2008; 46:42-49. Clin Toxicol 2008; 46:42-49.
IV. Bjornaas MA, Jacobsen D, Haldorsen T, Ekeberg O. Mortality and causes of death after hospital-treated self-poisoning in Oslo: A 20-year follow-up study. Clin Toxicol 2009; 47:116-23
V. Bjornaas MA, Bekken AS, Ojlert A, Haldorsen T, Jacobsen D, Rostrup M, Ekeberg O. A 20-year prospective study on mortality and causes of death among opioid addicts in Oslo. BMC Psychiatry 2008, 8:8 (13 February 2008). Article in full text to be found in the pdf-file
VI. Bjornaas MA, Hovda KE, Heyerdahl F, Skog K, Drottning P, Opdahl A, Jacobsen D, Ekeberg O. Suicidal intention, psychosocial factors and referral to further treatment – a one year cross-sectional study of self-poisonings. Submitted.