Drug-related problems in hospitalised patients : A prospective bedside study of an issue needing particular attention
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AbstractIn the case of most diseases drug therapy will enhance health-related quality of life. However, inappropriate use of drugs may be harmful and could evoke new adverse symptoms. This has been known for centuries but, it was first when the reports of aplastic anaemia following treatment with chloramphenicol (9) and of birth defects after use of thalidomide (10) that the interest in drug-related problems (DRPs) increased dramatically. Since then, research in this field has been intensified, as has the development of more effective and targeted drugs, and the pharmaceutical industry has grown into one of the most important industries in the world. A paradoxical consequence is that drug therapy has gradually become more complex, thus making it increasingly challenging to prescribe drugs appropriately.
List of papers
Paper I Blix HS, Viktil KK, Reikvam Å, Moger TA, Hjemaas BJ, Pretsch P, Vraalsen TF, Walseth EK. The majority of hospitalised patients have drug-related problems: results from a prospective study in general hospitals. Eur J Clin Pharmacol 2004;60(9):651-8 Abstract
Paper II Blix HS, Viktil KK, Moger TA, Reikvam Å. Characteristics of drug-related problems discussed by hospital pharmacists in multidisciplinary teams. Pharm World Sci 2006;28(3):152-8. Abstract
Paper III Blix HS, Viktil KK, Moger TA, Reikvam A. Use of renal risk drugs in hospitalized patients with impaired renal function – an underestimated problem? Nephrol Dial Transplant 2006;21(11):3164-71. Abstract
Paper IV Blix HS, Viktil KK, Moger TA, Reikvam A. Comparison of two methods for identification of drug interactions: computerised screening versus bedside recording. Submitted.