We studied the genetic epidemiology of primary large‐joint (hip and knee) osteoarthritis (OA), in order to find disease risk factors by a candidate‐gene approach. We used case–control study in the Croatian Caucasian ...

There is little evidence for the involvement of microRNAs (miRNAs) in the regulation of circadian rhythms during enamel development. Few studies have used ameloblast-like cell line LS8 to study the circadian rhythm of gene ...

Vancomycin resistant enterococci (VRE) belong to the most common causes of nosocomial infections worldwide. It has been reported that use of the glycopeptide growth promoter avoparcin selected for a significant livestock-reservoir ...

There is increasing evidence for an association between periodontitis/tooth loss and oral, gastrointestinal, and pancreatic cancers. Periodontal disease, which is characterized by chronic inflammation and microbial dysbiosis, ...

Chronic periodontitis of 10 years’ duration is reported to become a twofold risk factor for the development of Alzheimer’s disease (AD). Periodontitis is modifiable, and this fits with the current action plan for preventing ...

To date there is no cure available for dementia, and the field calls for novel therapeutic targets. A rapidly growing body of literature suggests that regular endurance training and high cardiorespiratory fitness attenuate ...

Acellular polymer-calcium phosphate composites are promising bone graft materials. Hydrogels are suitable for providing a temporary matrix, while calcium phosphate minerals serve as ion depots for calcium and phosphate ...

Purpose: Besides being actively metabolized, lactate may also function as a signaling molecule by activation of the G-protein–coupled receptor 81 (GPR81). Thus, we aimed to characterize the metabolic effects of GPR81 ...

Tannic acid (TA) adheres to a broad variety of different materials and forms versatile surface coatings for technical and biological applications. In mild alkaline conditions, autoxidation processes occur and a firm monolayer ...

MRONJ is a potentially serious complication of anti‐resorptive (AR) treatment in patients with skeletal metastases due to various cancers as well as osteoporosis (Campisi et al., 2014). MRONJ may also develop in ...

Both human and animal studies have shown mitochondrial and contractile dysfunction in hearts of type 2 diabetes mellitus (T2DM). Exercise training has shown positive effects on cardiac function, but its effect on the ...

The lack of knowledge regarding the long-term effect of retention on anterior tooth alignment provided much of the motivation for this research project. Further, the work would give information about long-term outcome of ...

Background In streptococci of the mitis group, competence for natural transformation is a transient physiological state triggered by competence stimulating peptides (CSPs). Although low transformation yields ...

Sammendrag Mens resistensutvikling etter bruk av antibiotika er velkjent, i rask utvikling og beskrevet som et stort miljø- og medisinsk problem, er resistens mot andre antimikrobielle midler, Metronidazol, antiseptika og ...

Introduction: Bacterial contamination of the temporomandibular joint (TMJ) by needle penetration of the skin has previously been discussed as a contributing factor in joint arthritis. The purpose of this study was to ...

For å bedre den orale helsen hos utsatte individer, samt tilby et bredere utvalg av forebyggende behandlingsmetoder, kan nanoteknologi muligens være med på å forme en fremtidig forebyggende behandling innenfor odontologien ...

Porphyromonas gingivalis is an anaerobic bacterium heavily associated with periodontitis, a chronic inflammatory disease resulting in the irreversible destruction of the periodontium. With a vast array of virulence factors ...

Masteroppgaven består i hovedsak av to deler – et litteratursøk og et klinisk forsøk. Den første delen med litteratursøk handler om bittskinner generelt for behandling av temporomandibulære plager, og den andre delen handler ...

Porphyromonas gingivalis is an anaerobic bacterium heavily associated with periodontitis, a chronic inflammatory disease resulting in the irreversible destruction of the periodontium. With a vast array of virulence factors ...

Background: Autoimmune polyendocrine syndrome type-1 (APS-1) is a rare, childhood onset disease caused by mutations in the Autoimmune Regulator gene. The phenotypic expression is highly variable and includes disease ...

Periodontitis, rheumatoid arthritis (RA), atherosclerosis (AS), and Alzheimer’s disease (AD) are examples of complex human diseases with chronic inflammatory components in their etiologies. The initial trigger of inflammation ...

The keystone periodontal pathogen Porphyromonas gingivalis produces phosphorylated dihydroceramide lipids (sphingolipids) such as phosphoethanolamine dihydroceramide (PE DHC) and phosphoglycerol dihydroceramide (PG DHC) ...

Porphyromonas gingivalis is considered a keystone pathogen in adult periodontitis but has also been associated with systemic diseases. It has a myriad of virulence factors that differ between strains. Genetic exchange and ...

Background In bone tissue engineering (BTE), extensive research into vascular endothelial growth factor A (VEGFA)-mediated angiogenesis has yielded inconsistent results. The aim of this study was to ...

A dense nerve plexus in the clear outer window of the eye, the cornea, can be imaged in vivo to enable non-invasive monitoring of peripheral nerve degeneration in diabetes. However, a limited field of view of corneal nerves, ...

Odontologisk aldersvurdering utføres for å finne en odontologisk alder som sammenfaller med et individs kronologiske alder. Visdomstennene er ofte brukt ved aldersbestemmelse hos ungdommer og unge voksne da de kan gi ...

Odontologisk aldersvurdering utføres for å finne en odontologisk alder som sammenfaller med et individs kronologiske alder. Visdomstennene er ofte brukt ved aldersbestemmelse hos ungdommer og unge voksne da de kan gi ...

Lipopolysaccharide (LPS) of Porphyromonas gingivalis exists in at least two known forms, O-LPS and A-LPS. A-LPS shows heterogeneity in which two isoforms designated LPS1,435/1,449 and LPS1,690 appear responsible for ...

Background and Objective Strontium (Sr) enhances osteogenic differentiation of certain multipotent cells. Periodontal ligament cells (PDLCs) are known to be multipotent, and Sr might be useful in periodontal bone tissue ...

Objectives Medication-related osteonecrosis of the jaw (MRONJ) has a wide range of prevalence, and a standard therapy has not yet been established. The aim of this study was to analyze the prevalence and initiating ...

Background Little is known about the financial costs that smoking adds to the lifetime treatment of periodontal disease. Methods The total lifetime cost of periodontal treatment was modeled using data from private ...

Whereas the p38 MAP kinase has largely been associated with anti-proliferative functions, several observations have indicated that it may also have positive effects on proliferation. In hepatocytes, we have found that p38 ...

Objective To examine the effect that the introduction of new diagnostic technology in obstetric care has had on fetal death. Data Source The Medical Birth Registry of Norway provided detailed medical information for ...

Objective: Consumption of acidic food and drinks is considered as important risk factor for development of dental erosion. There are several in vitro and in situ studies focusing on the risk indicators and preventive ...

Background: In Norway, for several dental conditions, a substantial part of treatment costs are reimbursed by the National Insurance Scheme. Ideally, the probability of receiving subsidized dental care (SDC) should be ...

Storage of human retinal pigment epithelium (hRPE) can contribute to the advancement of cell-based RPE replacement therapies. The present study aimed to improve the quality of stored hRPE cultures by identifying storage ...

Slurry behaviour has an important influence on the properties of ceramic scaffolds produced by the polymer sponge method. By adding chloride salts to the TiO2 slurry, the viscosity was increased depending on the chloride ...

Periodontitt og metabolsk syndrom er begge vanlig forekommende lidelser i befolkningen. Man har lenge visst at forekomsten av metabolsk syndrom har en genetisk predisposisjon. Alvorligheten av tilstanden kan øke på grunn ...

Sammendrag: Periodontitt og metabolsk syndrom er begge vanlig forekommende lidelser i befolkningen. Man har lenge visst at forekomsten av metabolsk syndrom har en genetisk predisposisjon. Alvorligheten av tilstanden kan ...

Introduksjon: Vitamin K-antagonisten warfarin har lenge vært standard antikoagulasjonspreparat, men grunnet medikamentets ulemper som behov for nøye monitorering, interaksjoner og alvorlige bivirkninger, har det vært ...

Objective: The first aim was to describe presence of plaque, caries and oral health behaviours in 2‐year‐old children. The second aim was to measure increments in caries experience from 2 to 5 years of age and to study ...

Quality assurance or quality control is a term and concept coming from the industry. Here it is most important. All products must have a minimum quality and variation in size, for example, must be kept within certain strict ...

Peroxisome proliferator-activated receptor-gamma coactivator (PGC1α) is a transcription coactivator that interacts with a broad range of transcription factors involved in several biological responses. Here, we show that ...

In this study, the effect on osteoclast activity in vitro and in vivo of titanium implants that were coated with quercitrin was evaluated. Titanium surfaces were covalently coated with the flavonoid quercitrin. The effect ...

Optic atrophy 1 (OPA1) is the A-kinase anchoring protein targeting the pool of protein kinase A (PKA) responsible for perilipin 1 phosphorylation, a gatekeeper for lipolysis. However, the involvement of OPA1-bound PKA in ...

Ocular dryness is a characteristic feature of primary Sjögren’s syndrome (pSS). This may result in dry eye disease (DED), leading to damage of the ocular surface. Additional, non-invasive diagnostic techniques are needed ...

Strategies that enable hydrogel substrates to support cell attachment typically incorporate either entire extracellular matrix proteins or synthetic peptide fragments such as the RGD (arginine–glycine–aspartic acid) motif. ...

Our research into Alzheimer’s disease (AD) focuses on the oral cavity and the brain, from which key evaluations of prospective and retrospective population-based data have shown that chronic periodontal disease existing ...

Hybrid poly(ethylene glycol)-co-peptide hydrogels are a versatile platform for bone regeneration. For the use as injectable scaffolds, a good understanding of reaction kinetics and physical properties is vital. However, ...

There is limited knowledge about dietary intake and body composition among patients with primary Sjögren’s syndrome. We assessed dietary intakes with 24-h recalls and body composition with anthropometry and bioelectrical ...

Background and Objective: Melatonin deficiency has been associated with obesity and systemic inflammation. This study aims to evaluate whether melatonin could interfere with the mechanisms of co‐morbidity linking obesity ...

Background Migraine is a common headache disorder that affects mostly women. In half of these, migraine is menstrually associated, and ranges from completely asymptomatic to frequent pain throughout ...

Outsourcing of scientific publishing to scientific journals is problematic, both economically and academically. It is expensive, slow, non-transparent, unbalanced and excluding. Academic library subscriptions contribute ...

Torture victims often show symptoms of dental anxiety when receiving dental care, but little systematic research is available. The purpose of this study was to explore torture experiences, symptoms of post‐traumatic stress ...

Aim: To assess the prevalence of proximal enamel lesions, the need for non-operative caries treatment and the quality of dental restorations in 869 students aged 16 years from Northern Norway. Methods: All first year ...

Objectives: The tasks of this working group were to evaluate the existing evidence on the efficiency and efficacy of the digital and conventional workflows for the fabrication of fixed implant reconstructions, to assess ...

TiO2 scaffolds have previously shown to have promising osteoconductive properties in previous in vivo experiments. Appropriate mechanical stimuli can further promote this osteoconductive behaviour. However, the complex ...

AIM: To use micro-CT technology and metrology software to validate the use of contralateral premolars as samples in endodontic comparison studies by comparing them before and after canal instrumentation with one instrumentation ...

Aims/hypothesis Although IL-1β is considered a key mediator of beta cell destruction, its cellular expression in islets during early type 1 diabetes remains unclear. We compared its expression in rare pancreatic biopsies ...

Purpose: To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear ...

Commensal microbes are currently in the limelight in biomedical research because they play an important role in health and disease. Humans harbor an enormous diversity of commensals in various parts of the body, including ...

Aims/hypothesis Sphingolipids play important roles in beta cell physiology, by regulating proinsulin folding and insulin secretion and in controlling apoptosis, as studied in animal models and cell cultures. Here we ...