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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The B cell receptors (BCRs) for antigen express variable (V) regions that are enormously diverse, thus serving as markers on individual B cells. V region-derived idiotypic (Id) peptides can be displayed as pId:MHCII complexes ...
How do CD4+ T cells detect and eliminate tumor cells that either lack or express MHC class II molecules?
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
CD4+ T cells contribute to tumor eradication, even in the absence of CD8+ T cells. Cytotoxic CD4+ T cells can directly kill MHC class II positive tumor cells. More surprisingly, CD4+ T cells can indirectly eliminate tumor ...