Now showing items 1-4 of 4

  • Holm, Laurits J.; Krogvold, Lars; Hasselby, Jane P.; Kaur, Simranjeet; Claessens, Laura A.; Russell, Mark A.; Mathews, Clayton E.; Hanssen, Kristian Folkvord; Morgan, Noel G.; Koeleman, Bobby P.C.; Roep, Bart O.; Gerling, Ivan C.; Pociot, Flemming; Dahl-Jørgensen, Knut; Buschard, Karsten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Aims/hypothesis Sphingolipids play important roles in beta cell physiology, by regulating proinsulin folding and insulin secretion and in controlling apoptosis, as studied in animal models and cell cultures. Here we ...
  • Reddy, Shiva; Krogvold, Lars; Martin, Charlton; Holland, Rebecca; Choi, Jaimin; Woo, Hannah; Wu, Fiona; Dahl-Jørgensen, Knut (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Aims/hypothesis Although IL-1β is considered a key mediator of beta cell destruction, its cellular expression in islets during early type 1 diabetes remains unclear. We compared its expression in rare pancreatic biopsies ...
  • Rodriguez-Calvo, Teresa; Zapardiel-Gonzalo, Jose; Amirian, Natalie; Castillo, Ericka; Lajevardi, Yasaman; Krogvold, Lars; Dahl-Jørgensen, Knut; Von Herrath, Matthias G. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Type 1 diabetes is characterized by the loss of insulin production caused by β-cell dysfunction and/or destruction. The hypothesis that β-cell loss occurs early during the prediabetic phase has recently been challenged. ...
  • Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E.; Licata, Giada; Krogvold, Lars; Marselli, Lorella; Gysemans, Conny; Overbergh, Lut; Marchetti, Piero; Mathieu, Chantal; Dahl-Jørgensen, Knut; Sebastiani, Guido; Dotta, Francesco (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    C-X-C Motif Chemokine Ligand 10 (CXCL10) is a pro-inflammatory chemokine specifically recognized by the ligand receptor CXCR3 which is mostly expressed in T-lymphocytes. Although CXCL10 expression and secretion have been ...