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Methacrylation increase growth and differentiation of primary human osteoblasts for gelatin hydrogels 
Sukul, Mousumi; Cama, Giuseppe; Dubruel, Peter; Reseland, Janne Elin; Haugen, Håvard Jostein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The role of gelatin methacrylate hydrogels with varying degree of methacrylation (69% and 84%) was accessed with FTIR, NMR, microCT and subsequently exposure to human osteoblasts. The cells responded positively to the ...
Melatonin expression in periodontitis and obesity: An experimental in-vivo investigation 
Leire, Virto; Haugen, Håvard Jostein; Fernández-mateos, Pilar; Cano, Pilar; González, Jerián; Jiménez-ortega, Vanesa; Esquifino, Ana isabel; Sanz Alonso, Mariano (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Background and Objective: Melatonin deficiency has been associated with obesity and systemic inflammation. This study aims to evaluate whether melatonin could interfere with the mechanisms of co‐morbidity linking obesity ...
Comparison of titanium dioxide scaffold with commercial bone graft materials through micro-finite element modelling in flow perfusion 
Zhang, Xianbin; Tiainen, Hanna; Haugen, Håvard Jostein (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
TiO2 scaffolds have previously shown to have promising osteoconductive properties in previous in vivo experiments. Appropriate mechanical stimuli can further promote this osteoconductive behaviour. However, the complex ...
Peri-Implant Soft Tissue Integration in Humans – Influence of Materials: A study protocol for a randomised controlled trial and a pilot study results 
Borie, Manon; Lecloux, Geoffrey; Bosshardt, Dieter D.; Haugen, Håvard Jostein; Lambert, France; Bacevic, Miljana (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background : Recently, there has been a growing interest in mucointegration as the formation of an early and long-standing soft tissue barrier seems essential for both the initial healing and long-term implant survival. ...
Validation of contralateral premolars as the substrate for endodontic comparison studies 
Johnsen, Gaute Floer; Sunde, Pia Titterud; Haugen, Håvard Jostein (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
AIM: To use micro-CT technology and metrology software to validate the use of contralateral premolars as samples in endodontic comparison studies by comparing them before and after canal instrumentation with one instrumentation ...
Grain boundary corrosion in TiO2 bone scaffolds doped with group II cations 
Klemm, Anne; Gomez-Florit, Manuel; Carvalho, Patricia A.; Wachendörfer, Mattis; Gomes, Manuela E.; Haugen, Håvard Jostein; Tiainen, Hanna (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
A pH drop during the inflammatory phase during bone regeneration can cause corrosion in TiO2 bone scaffolds and the loss of compressive strength. Corrosion as ion leaching and dissolution is confined to grain boundaries. ...
Bone grafts: which is the ideal biomaterial? 
Haugen, Håvard Jostein; Lyngstadaas, Ståle Petter; Rossi, Filippo; Perale, Giuseppe (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
Abstract Bovine xenograft materials, followed by synthetic biomaterials, which unfortunately still lack documented predictability and clinical performance, dominate the market for the cranio‐maxillofacial area. In Europe, ...
Structural and Chemical Hierarchy in Hydroxyapatite Coatings 
Gross, Karlis Agris; Petzold, Christiane; Pluduma, Liene; Kumermanis, Maris; Haugen, Håvard Jostein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Hydroxyapatite coatings need similarly shaped splats as building blocks and then a homogeneous microstructure to unravel the structural and chemical hierarchy for more refined improvements to implant surfaces. Coatings ...
Poly-L-lysine/heparin multilayer coatings prevent blood protein adsorption 
Barrantes Bautista, Alejandro; Wengenroth, Jonas; Arnebrant, Thomas; Haugen, Håvard Jostein (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The adsorption of blood proteins, serum albumin (BSA), immunoglobulin G (IgG) and fibrinogen (FGN), onto model SiO2 planar surfaces coated with poly-l-lysine/heparin multilayers (PLL/HEP) has been investigated by means of ...
Alginate hydrogel enriched with enamel matrix derivative to target osteogenic cell differentiation in TiO2 scaffolds 
Pullisaar, Helen; Verket, Anders; Szoke, Krisztina; Tiainen, Hanna; Haugen, Håvard Jostein; Brinchmann, Jan E.; Reseland, Janne Elin; Østrup, Esben (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The purpose of bone tissue engineering is to employ scaffolds, cells, and growth factors to facilitate healing of bone defects. The aim of this study was to assess the viability and osteogenic differentiation of primary ...
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