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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Alzheimer’s disease (AD) has been associated with periodontitis, which starts as gingivitis. Similar to periodontitis, gingivitis bacteria, bacterial products, and inflammatory mediators can travel to the brain via the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Iron accumulates in the brain of subjects with Alzheimer’s disease (AD). Here it promotes the aggregation of amyloid-β plaques in which it is abundant. Iron induces amyloid-β neurotoxicity by damaging free radicals and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
“Chronic” periodontitis and its keystone pathogen Porphyromonas gingivalis have repeatedly been associated with Alzheimer’s disease (AD). Pathological hallmarks in AD are brain accumulations of amyloid-beta and neurofibrillary ...