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Attenuation of Candida albicans virulence with focus on disruption of its vacuole functions 
Olsen, Ingar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The objective of the present review is to discuss if the yeast vacuole can be used as a target for attenuation of Candida albicans virulence. Literature searches were made electronically using predetermined inclusion ...
In silico Comparison of 19 Porphyromonas gingivalis Strains in Genomics, Phylogenetics, Phylogenomics and Functional Genomics 
Chen, Tsute; Siddiqui, Huma; Olsen, Ingar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Currently, genome sequences of a total of 19 Porphyromonas gingivalis strains are available, including eight completed genomes (strains W83, ATCC 33277, TDC60, HG66, A7436, AJW4, 381, and A7A1-28) and 11 high-coverage draft ...
Extended-spectrum beta-lactamase-producing bacteria are not detected in supragingival plaque samples from human fecal carriers of ESBL-producing Enterobacteriaceae 
Søraas, Arne Vasli Lund; Olsen, Ingar; Sundsfjord, Arnfinn; Handal, Trude; Bjørang, Ola; Jenum, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: The prevalence of infections caused by Cefotaximase-Munich (CTX-M)-type extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has rapidly increased during the past 15 years. Enterobacteriaceae ...
Outer membrane vesicles - offensive weapons or good Samaritans? 
Olsen, Ingar; Amano, Atsuo (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Outer membrane vesicles (OMVs) from Gram-negative bacteria were first considered as artifacts and were followed with disbelief and bad reputation. Later, their existence was accepted and they became characterized as bacterial ...
Genome sequence of Porphyromonas gingivalis strain HG66 (DSM28984) 
Siddiqui, Huma; Yoder-Himes, Deborah Ruth; Mizgalska, Danuta; Nguyen, Ky-Anh; Potempa, Jan; Olsen, Ingar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Porphyromonas gingivalis is considered a major etiologic agent in adult periodontitis. Gingipains are among its most important virulence factors, but their release is unique in strain HG66. We present the genome sequence ...
Bacteria and bacterial DNA in atherosclerotic plaque and aneurysmal wall biopsies from patients with and without periodontitis 
Armingohar, Zahra; Jørgensen, Jørgen J.; Kristoffersen, Anne Karin; Abesha-Belay, Emnet; Olsen, Ingar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Several studies have reported an association between chronic periodontitis (CP) and cardiovascular diseases. Detection of periodontopathogens, including red complex bacteria (RCB), in vascular lesions has ...
Microbiological and bioinformatics analysis of primary Sjogren's syndrome patients with normal salivation 
Siddiqui, Huma; Chen, Tsute; Aliko, Ardita; Mydel, Piotr Mateusz; Jonsson, Roland; Olsen, Ingar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background: Reduced salivation is considered a major clinical feature of most but not all cases of primary Sjögren’s syndrome (pSS). Reduced saliva flow may lead to changes in the salivary microbiota. These changes have ...
Strategies for the inhibition of gingipains for the potential treatment of periodontitis and systemic diseases 
Olsen, Ingar; Potempa, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Gingipains are the major virulence factors of Porphyromonas gingivalis, the main periodontopathogen. It is expected that inhibition of gingipain activity in vivo could prevent or slow down the progression of adult ...
Comparative genomics and proteomics of 13 Porphyromonas gingivalis strains 
Chen, Tsute; Siddiqui, Huma; Olsen, Ingar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
At the current time, genome sequences of a total of 13 Porphyromonas gingivalis strains are available, including five completed genomes (strains ATCC 33277, HG66, TDC60, JCVISC001, and W83) and eight high-coverage draft ...
Can oral infection be a risk factor for Alzheimer’s disease? 
Olsen, Ingar; Singhrao, Sim K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Alzheimer’s disease (AD) is a scourge of longevity that will drain enormous resources from public health budgets in the future. Currently, there is no diagnostic biomarker and/or treatment for this most common form of ...
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