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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The idea of a bioactive surface coating that enhances bone healing and bone growth is a strong focus of on-going research for bone implant materials. Enamel matrix derivate (EMD) is well documented to support bone regeneration ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
The aim of this study was to develop a three-dimensional porous bone graft material as vehicle for simvastatin delivery and to investigate its effect on primary human osteoblasts from three donors. Highly porous titanium ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The purpose of bone tissue engineering is to employ scaffolds, cells, and growth factors to facilitate healing of bone defects. The aim of this study was to assess the viability and osteogenic differentiation of primary ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
We have studied the effect of chitosan sponges, produced from chitosan batches with distinct degree of deacetylation (DDA) and molecular weight (Mw), on the adhesion, growth and differentiation of primary human osteoblasts ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Bone defects resulting from trauma, surgery, congenital malformations, and other factors are among the most common health problems nowadays. Although current strategies such as autografts and allografts are recognized as ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2023)
Biphasic monolithic materials for the treatment of osteochondral defects were produced from polysaccharide hydrogel, gellan gum (GG). GG was enzymatically mineralized by alkaline phosphatase (ALP) in the presence of calcium ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
ABSTRACT In vitro models of primary human osteocytes embedded in natural mineralized matrix without artificial scaffolds are lacking. We have established cell culture conditions that favored the natural 3D orientation of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The attachment of implants rely on bone and soft tissue biocompatibility. The aim was to investigate the effect of fluoride modified metallic titanium (Ti) surfaces (Ti-F) on proliferation and differentiation of human ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Regardless of the substantial progress in designing titanium-based dental implants and aseptic techniques, infection remains as the most common complication after implantation surgeries. Although, having a weakened immune ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Immediately after dental implant insertion, blood will be in direct contact and interact with the implant surface and activates inflammatory responses and complement cascades within seconds. The aim of the present study ...