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Now showing items 31-40 of 46
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Chronic periodontitis of 10 years’ duration is reported to become a twofold risk factor for the development of Alzheimer’s disease (AD). Periodontitis is modifiable, and this fits with the current action plan for preventing ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
There is increasing evidence for an association between periodontitis/tooth loss and oral, gastrointestinal, and pancreatic cancers. Periodontal disease, which is characterized by chronic inflammation and microbial dysbiosis, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The clustered regularly interspaced short palindromic repeats (CRISPRs) and their associated proteins (Cas) are immune systems in prokaryotes present in most Bacteria and Archaea. They provide adaptive immunity against ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Inflammasomes are responsible for the maturation of pro-inflammatory cytokines such as interleukin (IL)-1β, IL-18, and IL-33 and activation of inflammatory cell death, pyroptosis. They assemble in response to cellular ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Porphyromonas gingivalis is a Gram-negative anaerobic rod that has been proposed as an orchestrator of complement-dependent dysbiotic inflammation. This notion was suggested from its capacities to manipulate the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
As far back as the eighteenth and early nineteenth centuries, microbial infections were responsible for vast numbers of deaths. The trend reversed with the introduction of antibiotics coinciding with longer life. Increased ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The sporadic form of Alzheimer’s disease (AD) is the most common form of dementia characterized microscopically by the presence of amyloid-beta (Aβ) plaques and tau neurofibrillary tangles with the clinical presentation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Oral bacteria spreading through the body have been associated with a number of systemic diseases. The gut is no exception. Studies in animals and man have indicated that oral bacteria can translocate to the gut and change ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Our research into Alzheimer’s disease (AD) focuses on the oral cavity and the brain, from which key evaluations of prospective and retrospective population-based data have shown that chronic periodontal disease existing ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Alzheimer’s disease (AD) has been associated with periodontitis, which starts as gingivitis. Similar to periodontitis, gingivitis bacteria, bacterial products, and inflammatory mediators can travel to the brain via the ...