Browsing Øvrige samlinger by Author "Winiarska, Magdalena"

Now showing items 1-3 of 3

  • Efficient chimeric antigen receptor targeting of a central epitope of CD22 
    Casey, Nicholas Paul; Klee, Clara Helena; Bøthun, Anne Fåne; Caulier, Benjamin William; Graczyk-Jarzynka, Agnieszka; Krawczyk, Marta; Fidyt, Klaudyna; Josefsson, Sarah Elisabet; Köksal, Hakan; Dillard, Pierre; Patkowska, Elzbieta; Firczuk, Malgorzata; Smeland, Erlend Bremertun; Winiarska, Magdalena; Myklebust, June Helen; Inderberg, Else Marit; Wälchli, Sébastien (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Chimeric antigen receptor (CAR) T-cell therapy has had considerable success in the treatment of B-cell malignancies. Targeting the B-lineage marker CD19 has brought great advances to the treatment of acute lymphoblastic ...
  • Intrinsic functional potential of NK-Cell subsets constrains retargeting driven by chimeric antigen receptors 
    Oei, Vincent Yi Sheng; Siernicka, Marta; Graczyk-Jarzynka, Agnieszka; Hoel, Hanna Julie; Yang, Weiwen; Palacios Orellana, Daniel Alfredo; Almåsbak, Hilde Kjersti; Bajor, Malgorzata; Clement, Dennis; Brandt, Ludwig; Önfelt, Björn; Goodridge, Jodie; Winiarska, Magdalena; Zagozdzon, Radoslaw; Olweus, Johanna; Kyte, Jon A; Malmberg, Karl-Johan (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Natural killer (NK) cells hold potential as a source of allogeneic cytotoxic effector cells for chimeric antigen receptor (CAR)-mediated therapies. Here, we explored the feasibility of transfecting CAR-encoding mRNA into ...
  • PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells 
    Bajor, Malgorzata; Graczyk-Jarzynka, Agnieszka; Marhelava, Katsiaryna; Burdzinska, Anna; Muchowicz, Angelika; Goral, Agnieszka; Zhylko, Andriy; Soroczynska, Karolina; Retecki, Kuba; Krawczyk, Marta; Klopotowska, Marta; Pilch, Zofia; Paczek, Leszek; Malmberg, Karl-Johan; Wälchli, Sébastien; Winiarska, Magdalena; Zagozdzon, Radoslaw (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Immune checkpoint inhibitors and chimeric antigen receptor (CAR)-based therapies have transformed cancer treatment. Recently, combining these approaches into a strategy of PD-L1-targeted CAR has been proposed ...