Now showing items 1-5 of 5

  • Bogdanova, Mariia; Kostina, Aleksandra; Zihlavnikova, Katarina; Malashicheva, Anna; Stensløkken, Kåre-Olav; Sullivan, Gareth; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Kostareva, Anna; Vaage, Ingvar Jarle; Rutkovskiy, Arkady (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: Aortic valve calcification is an active proliferative process, where interstitial cells of the valve transform into either myofibroblasts or osteoblast-like cells causing valve deformation, thickening of cusps ...
  • Mariero, Lars Henrik; Torp, May-Kristin; Heiestad, Christina Mathisen; Baysa, Anton; Li, Yuchuan; Valen, Guro; Vaage, Ingvar Jarle; Stensløkken, Kåre-Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background and purpose Cellular debris causes sterile inflammation after myocardial infarction. Mitochondria constitute about 30 percent of the human heart. Mitochondrial DNA (mtDNA) is a damage‐associated‐molecular‐pattern ...
  • Stensløkken, Kåre-Olav; Ellefsen, Stian; Vasieva, Olga; Fang, Youhan; Farrell, Anthony P.; Olohan, Lisa; Vaage, Ingvar Jarle; Nilsson, Göran Erik; Cossins, Andrew R. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a ...
  • Reine, Trine M.; Vuong, Tram Thu; Rutkovskiy, Arkady; Meen, Astri Jeanette; Vaage, Ingvar Jarle; Jenssen, Trond Geir; Kolset, Svein Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Proteoglycans are fundamental components of the endothelial barrier, but the functions of the proteoglycan serglycin in endothelium are less described. Our aim was to describe the roles of serglycin in processes relevant ...
  • Zabirnyk, Arsenii; Ferrer, Miguel David; Bogdanova, Maria A; Perez, MM; Salcedo, C; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Stensløkken, Kåre-Olav; Perello, Joan; Vaage, Ingvar Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The purpose of the present study was to investigate whether SNF472, the hexasodium salt of myo-inositol hexaphosphate (IP6 or phytate): 1. Inhibits induced calcification in cultured aortic valve interstitial cells (VIC) ...