Browsing Øvrige samlinger by Author "Fauskanger, Marte"

Now showing items 1-5 of 5

  • CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models 
    Bogen, Bjarne; Fauskanger, Marte; Haabeth, Ole Audun; Tveita, Anders Aune (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    It is well recognized that CD4+ T cells may play an important role in immunosurveillance and immunotherapy against cancer. However, the details of how these cells recognize and eliminate the tumor cells remain incompletely ...
  • CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages 
    Haabeth, Ole Audun; Hennig, Kjartan; Fauskanger, Marte; Løset, Geir Åge; Bogen, Bjarne; Tveita, Anders Aune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract CD4+ T cells may induce potent antitumor immune responses through interaction with antigen-presenting cells within the tumor microenvironment. Using a murine model of multiple myeloma, we demonstrated ...
  • Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules 
    Andersen, Tor Kristian; Huszthy, Peter Csaba; Gopalakrishnan, Ramakrishna Prabhu; Jacobsen, Johanne Tracey; Fauskanger, Marte; Tveita, Anders Aune; Grødeland, Gunnveig; Bogen, Bjarne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Enhancing the germinal center (GC) reaction is a prime objective in vaccine development. Targeting of antigen to MHCII on APCs has previously been shown to increase antibody responses, but the underlying mechanism has been ...
  • Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models 
    Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Mahmuda, Shoshy (Brinch, Shoshy Alam); Lycke, Eric Maximilian; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre; Krauss, Stefan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    The development of immune checkpoint inhibitors represents a major breakthrough in cancer therapy. Nevertheless, a substantial number of patients fail to respond to checkpoint pathway blockade. Evidence for WNT/β-catenin ...
  • Tumor killing by CD4+ T cells is mediated via induction of inducible nitric oxide synthase-dependent macrophage cytotoxicity 
    Fauskanger, Marte; Haabeth, Ole Audun; Skjeldal, Frode Miltzow; Bogen, Bjarne; Tveita, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    CD4+ T cells can induce potent anti-tumor immune responses. Due to the lack of MHC class II expression in most cancer cells, antigen recognition occurs indirectly via uptake and presentation on tumor-infiltrating ...