Browsing Øvrige samlinger by Author "Zabirnyk, Arsenii"

Now showing items 1-5 of 5

  • A Novel Ex Vivo Model of Aortic Valve Calcification. A Preliminary Report 
    Zabirnyk, Arsenii; Perez, Maria del Mar; Blasco, Marc; Stensløkken, Kåre-Olav; Ferrer, Miguel D.; Salcedo, Carolina; Vaage, Ingvar Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background: No pharmacological treatment exists to prevent or stop the calcification process of aortic valves causing aortic stenosis. The aim of this study was to develop a robust model of induced calcification in whole ...
  • Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties. 
    Bogdanova, Mariia; Kostina, Aleksandra; Zabirnyk, Arsenii; Malashicheva, Anna; Enayati, a; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Dissen, Erik; Sullivan, Gareth; Kostareva, Anna; Stensløkken, Kåre-Olav; Rutkovskiy, Arkady; Vaage, Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Valve interstitial cells (VICs) are crucial in the development of calcific aortic valve disease. The purpose of the present investigation was to compare the phenotype, differentiation potential and stem cell-like properties ...
  • Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview 
    Bogdanova, Mariia; Zabirnyk, Arsenii; Malashicheva, Anna; Semenova, Daria; Kvitting, John-Peder; Kaljusto, Mari-Liis; Perez, Maria del Mar; Kostareva, Anna; Stensløkken, Kåre-Olav; Sullivan, Gareth John; Rutkovskiy, Arkady; Vaage, Ingvar Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve ...
  • Multi-omics of in vitro aortic valve calcification 
    Semenova, Daria; Zabirnyk, Arsenii; Lobov, Arseniy; Boyarskaya, Nadezda; Kachanova, Olga; Uspensky, Vladimir; Zainullina, Bozhana; Denisov, Evgeny; Gerashchenko, Tatiana; Kvitting, John-Peder; Kaljusto, Mari-Liis; Thiede, Bernd; Kostareva, Anna; Stensløkken, Kåre-Olav; Vaage, Ingvar Jarle; Malashicheva, Anna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Heart valve calcification is an active cellular and molecular process that partly remains unknown. Osteogenic differentiation of valve interstitial cells (VIC) is a central mechanism in calcific aortic valve disease (CAVD). ...
  • SNF472, a novel anti-crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification 
    Zabirnyk, Arsenii; Ferrer, Miguel David; Bogdanova, Maria A; Perez, MM; Salcedo, C; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Stensløkken, Kåre-Olav; Perello, Joan; Vaage, Ingvar Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The purpose of the present study was to investigate whether SNF472, the hexasodium salt of myo-inositol hexaphosphate (IP6 or phytate): 1. Inhibits induced calcification in cultured aortic valve interstitial cells (VIC) ...