Browsing Øvrige samlinger by Author "Fuchs, Claudia Daniela"

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  • Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis 
    Reich, Maria; Spomer, Lina; Klindt, Caroline; Fuchs, Katharina; Stindt, Jan; Deutschmann, Kathleen; Höhne, Johanna; Liaskou, Evaggelia; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Beuers, Ulrich; Verheij, Joanne; Ferreira-Gonzalez, Sofia; Hirschfield, Gideon; Forbes, Stuart J.; Schramm, Christoph; Esposito, Irene; Nierhoff, Dirk; Fickert, Peter; Fuchs, Claudia Daniela; Trauner, Michael; Garcia-Beccaria, Maria; Gabernet, Gisela; Nahnsen, Sven; Mallm, Jan-Philipp; Vogel, Marina; Schoonjans, Kristina; Lautwein, Tobias; Köhrer, Karl; Häussinger, Dieter; Luedde, Tom; Heikenwalder, Mathias; Keitel, Verena (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background & Aims Primary sclerosing cholangitis (PSC) is characterized by chronic inflammation and progressive fibrosis of the biliary tree. The bile acid receptor TGR5 (GPBAR1) is found on biliary epithelial cells ...
  • FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2 
    Brevini, Teresa; Maes, Mailis; Webb, Gwilym J; John, Binu V; Fuchs, Claudia Daniela; Buescher, Gustav; Wang, Lu; Griffiths, Chelsea; Brown, Marnie L; Scott 3rd, William E; Pereyra-Gerber, Pehuen; Gelson, William T H; Brown, Stephanie; Dillon, Scott; Muraro, Danielle; Sharp, Jo; Neary, Megan; Box, Helen; Tatham, Lee; Stewart, James; Hagstrøm, Hannes; Melum, Espen; Barritt 4th, Alfred S; Gupta, Ravindra K.; Baker, Stephen; Davenport, Antony P; Corbett, Gareth; Gorgoulis, Vassilis G; Bauzacki, Simon J A; Lee, Joo-Hyeon; Matheson, Nicholas J; Trauner, Michael; Fisher, Andrew J; Gibbs, Paul; Butler, Andrew J.; Watson, Christopher J E; Mells, Georg F; Dougan, Gordon; Owen, Andrew; Lohse, Ansgar W.; Vallier, Ludovic; Sampaziotis, Fotios (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Preventing SARS-CoV-2 infection by modulating viral host receptors, such as angiotensin-converting enzyme 2 (ACE2) 1 , could represent a new chemoprophylactic approach for COVID-19 that complements vaccination 2,3 ...