Browsing Øvrige samlinger by Title

Now showing items 29374-29393 of 34503

  • T cell and monocyte/macrophage activation markers associate with adverse outcome, but give limited prognostic value in anemic patients with heart failure: results from RED-HF 
    Abraityte, Judita Aurelija; Aukrust, Pål; Kou, Lei; Anand, Inder S.; Young, James; McMurray, John J.V.; van Veldhuisen, Dirk J.; Gullestad, Lars; Ueland, Thor (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
    Background Activated leukocytes may contribute to the development and progression of heart failure (HF). We investigated the predictive value of circulating levels of stable and readily detectable markers reflecting ...
  • T cell deletional tolerance restricts AQP4 but not MOG CNS autoimmunity 
    Sagan, Sharon A.; Moinfar, Zahra; Moseley, Carson E.; Dandekar, Ravi; Spencer, Collin M.; Verkman, Alan S.; Ottersen, Ole Petter; Sobel, Raymond A.; Sidney, John; Sette, Alessandro; Anderson, Mark S.; Steinman, Lawrence; Wilson, Michael R.; Sabatino, Joseph J.; Zamvil, Scott S. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Aquaporin-4 (AQP4)-specific Th17 cells are thought to have a central role in neuromyelitis optica (NMO) pathogenesis. When modeling NMO, only AQP4-reactive Th17 cells from AQP4-deficient (AQP4−/−), but not wild-type (WT) ...
  • T Cell Metabolism in Infection 
    Wik, Jonas Aakre; Skålhegg, Bjørn Steen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    T lymphocytes (T cells) are divided into two functionally different subgroups the CD4+ T helper cells (Th) and the CD8+ cytotoxic T lymphocytes (CTL). Adequate CD4 and CD8 T cell activation to proliferation, clonal expansion ...
  • T cell receptor repertoire as a potential diagnostic marker for celiac disease 
    Yao, Ying; Zia, Asima; Neumann, Ralf Stefan; Pavlović, Milena; Balaban, Gabriel; Lundin, Knut Erik Aslaksen; Sandve, Geir Kjetil; Qiao, Shuo Wang (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    An individual's T cell repertoire is skewed towards some specificities as a result of past antigen exposure and subsequent clonal expansion. Identifying T cell receptor signatures associated with a disease is challenging ...
  • T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases 
    Høye, Eirik; Dagenborg, Vegar Johansen; Kristensen, Annette Torgunrud; Lund-Andersen, Christin; Fretland, Åsmund Avdem; Lorenz, Susanne; Edwin, Bjørn von Gohren; Hovig, Eivind; Fromm, Bastian; Inderberg, Else Marit; Greiff, Victor; Ree, Anne Hansen; Flatmark, Kjersti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Background Colorectal liver metastasis (CLM) is a leading cause of colorectal cancer mortality, and the response to immune checkpoint inhibition (ICI) in microsatellite-stable CRC ...
  • T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation 
    McAdam, Stephen N.; Fleckenstein, Burkhard; Rasmussen, Ingunn B; Sandlie, Inger; Bogen, Bjarne; Vinter, N.J.; Sollid, Ludvig Magne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)
    Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to I-A(k) in different conformations. ...
  • T Cell Responses and Regulation and the Impact of In Vitro IL-10 and TGF-beta Modulation During Treatment of Active Tuberculosis 
    Feruglio, Siri; Kvale, Dag; Dyrhol-Riise, Anne Ma (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ...
  • T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis 
    Wolf, Asia-Sophia Fumika Michaela; Ravussin, Anthony; König, Marton; Øverås, Mathias Herstad; Solum, Guri; Kjønstad, Ingrid Fadum; Chopra, Adity; Holmøy, Trygve; Harbo, Hanne-Cathrin Flinstad; Syversen, Silje Watterdal; Jørgensen, Kristin Kaasen; Høgestøl, Einar August; Vaage, John T.; Celius, Elisabeth Gulowsen; Lund-Johansen, Fridtjof; Munthe, Ludvig Andre; Nygaard, Gro Owren; Mjaaland, Siri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Immune responses in people with multiple sclerosis (pwMS) receiving disease-modifying therapies (DMTs) have been of significant interest throughout the COVID-19 pandemic. Lymphocyte-targeting immunotherapies, including ...
  • T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells 
    Hem, Cecilie D; Sundvold-Gjerstad, Vibeke; Granum, Stine; Koll, Lise; Abrahamsen, Greger; Buday, Laszlo; Spurkland, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background The Lck and Src binding adaptor protein TSAd (T cell specific adaptor) regulates actin polymerization in T cells and endothelial cells. The molecular details as to how TSAd regulates this process ...
  • T cells expressing checkpoint receptor TIGIT are enriched in follicular lymphoma tumors and characterized by reversible suppression of T-cell receptor signaling 
    Josefsson, Sarah Elisabet Göthberg; Huse, Kanutte; Kolstad, Arne; Beiske, Klaus; Pende, Daniela; Steen, Chloe Beate; Inderberg, Else Marit; Lingjærde, Ole Christian; Østenstad, Bjørn; Smeland, Erlend B; Levy, Ronald; Irish, Jonathan M.; Myklebust, June (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Purpose: T cells infiltrating follicular lymphoma (FL) tumors are considered dysfunctional, yet the optimal target for immune checkpoint blockade is unknown. Characterizing coinhibitory receptor expression patterns and ...
  • T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes 
    Ali, Muhammad; Giannakopoulou, Eirini Chrysovalantou; Li, Yingqian; Lehander, Madeleine; Virding Culleton, Stina; Yang, Weiwen; Knetter, Cathrine; Odabasi, Mete Can; Bollineni, Ravi Chand; Yang, Xinbo; Foldvari, Zsofia; Böschen, Maxi-Lu; Taraldsrud, Eli; Strønen, Erlend; Toebes, Mireille; Hillen, Amy; Mazzi, Stefania; de Ru, Arnoud H.; Janssen, George M. C.; Kolstad, Arne; Tjønnfjord, Geir Erland; Lie, Benedicte Alexandra; Griffioen, Marieke; Lehmann, Sören; Osnes, Liv Toril; Buechner, Jochen; Garcia, K. Christopher; Schumacher, Ton N.; van Veelen, Peter A.; Leisegang, Matthias; Jacobsen, Sten Eirik W.; Woll, Petter; Olweus, Johanna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we demonstrate that T cells expressing TCRs specific for ...
  • T-cell Receptor Excision Circles in Newborns with Heart Defects 
    Gul, Kiran Aftab; Strand, Janne Maren; Pettersen, Rolf Dagfinn; Brun, Henrik; Abrahamsen, Tore G (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract In the fetus, the cardiac neural crest gives rise to both the thymus and the conotruncus of the heart. In newborn screening for severe T-cell lymphopenia neonates with congenital heart defects may be detected. In ...
  • T-helper cell regulation of CD45 phosphatase activity by galectin-1 and CD43 governs chronic lymphocytic leukaemia proliferation 
    Imbery, John Franklin; Heinzelbecker, Julia; Jebsen, Jenny K.; McGowan, Marc Kevin; Myklebust, Camilla Victoria; Bottini, Nunzio; Stanford, Stephanie M.; Skånland, Sigrid S; Tveita, Anders Aune; Tjønnfjord, Geir Erland; Munthe, Ludvig Andre; Szodoray, Peter; Nakken, Britt (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Chronic lymphocytic leukaemia (CLL) is characterised by malignant mature-like B cells. Supportive to CLL cell survival is chronic B-cell receptor (BCR) signalling; however, emerging evidence demonstrates CLL cells proliferate ...
  • The T-Reflection and the Deep Crustal Structure of the Vøring Margin, Offshore mid-Norway 
    Abdelmalak, Mohamed Mansour; Faleide, Jan Inge; Planke, Sverre; Gernigon, Laurent; Zastrozhnov, Dmitry; Shephard, Grace; Myklebust, Reidun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Seismic reflection data along volcanic passive margins frequently provide imaging of strong and laterally continuous reflections in the middle and lower crust. We have completed a detailed 2‐D seismic interpretation of the ...
  • t-tests, non-parametric tests, and large studies—a paradox of statistical practice? 
    Fagerland, Morten W (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background During the last 30 years, the median sample size of research studies published in high-impact medical journals has increased manyfold, while the use of non-parametric tests has increased at the ...
  • T. Douglas Price: Ancient Scandinavia. An Archaeological History from the First Humans to the Vikings. Oxford University Press, Oxford, 2015. 
    Prescott, Christopher (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    Review of "T. Douglas Price: Ancient Scandinavia. An Archaeological History from the First Humans to the Vikings" and more general discussion of curriculum in archaeological training
  • T1 bladder cancer in Norway: treatment and survival 
    Blindheim, Augun Jodis; Fosså, Sophie Dorothea; Babigumira, Ronnie; Myklebust, Tor Åge; Haug, Erik Skaaheim; Arum, Carl-Jørgen; Kulle, Bettina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Aim: Evaluation of treatment and survival of pT1 stage (T1) bladder cancer (BC) patients diagnosed with transitional cell carcinoma of the urinary bladder in Norway. Material and methods: According to the Cancer Registry ...
  • Ta3N5/Co(OH)x composites as photocatalysts for photoelectrochemical water splitting 
    Xu, Kaiqi; Chatzitakis, Athanasios Eleftherios; Jensen, Ingvild Julie Thue; Grandcolas, Mathieu; Norby, Truls Eivind (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
    Ta3N5 nanotubes (NTs) were obtained from nitridation of Ta2O5 NTs, which were grown directly on Ta foil through a 2-step anodization procedure. With Co(OH)x decoration, a photocurrent density as high as 2.3 mA cm−2 (1.23 ...
  • Taalvariatie op de Vlaamse openbare omroep: Substandaardisering in fictieprogramma’s vroeger en nu 
    Van Hoof, Sarah (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2010)
  • Tablet assessment of word comprehension reveals coarse word representations in 18–⁠20‐month‐old toddlers 
    Lo, Chang Huan; Rosslund, Audun; Chai, Jun Ho; Mayor, Julien; Kartushina, Natalia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The present study explores the viability of using tablets in assessing early word comprehension by means of a two‐alternative forced‐choice task. Forty‐nine 18–20‐month‐old Norwegian toddlers performed a touch‐based word ...