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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
Background
Efficient expression systems exist for antibody (Ab) molecules, which allow for characterization of large numbers of individual Ab variants. In contrast, such expression systems have been lacking ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
The neonatal Fc receptor (FcRn) regulates the serum half-life of both IgG and albumin through a pH-dependent mechanism that involves salvage from intracellular degradation. Therapeutics and diagnostics built on IgG, Fc, ...