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Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Objectives: To develop and validate a genetic tool to predict age of onset of aggressive prostate cancer (PCa) and to guide decisions of who to screen and at what age. Design: Analysis of genotype, PCa status, and age ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
Several oncogenic factors have been involved in prostate cancer progression. However, therapeutic approaches still focus on suppression of androgen receptor (AR) signaling. In fact, whereas the full-length AR incorporates ...