Background The underlying nature of negative symptoms in psychosis is poorly understood. Investigation of the relationship between the different negative subsymptoms and neurocognition is one approach to ...

Schizophrenia is a severe multifactorial mental disorder with an important and complex genetic component, and the understanding of the underlying biological mechanisms is limited. Several lines of evidence support that ...

Background There are conflicting results on whether immigrant children are at a heightened risk of mental health problems compared with native youth in the resettlement country. ...

Background Addressing substance use disorders effectively requires a long-term approach. Substance abuse treatment is typically of short duration; referring patients to Twelve Step based self-help groups ...

Background Several studies with conflicting findings have investigated the association between acne and mental health problems. Acne usually starts in adolescents, as does an increase in the prevalence of ...

Oesophageal atresia is a common congenital anomaly, embracing a clinically heterogeneous group of patients concerning seriousness of the medical condition, additional malformations and complications. Increased risk for ...

Lege og forsker Petter Andreas Ringen har undersøkt bruken av rusmidler i de to store psykiatriske diagnosegruppene schizofreni og bipolar lidelse. I sin avhandling Substance use in psychotic disorder; use patterns and ...

Schizophrenia is one of the most severe and disabling mental illnesses. In spite of continuous development of treatment modalities, most patients still suffer from chronic symptoms and functional decline. The precise ...

Background The long-term impact of opioid maintenance treatment (OMT) on morbidity and health care utilization among heroin addicts has been insufficiently studied. The objective of this study was to ...

Background Schizophrenia is a highly heritable complex psychiatric disorder with an underlying pathophysiology that is still not well understood. Metaanalyses of schizophrenia linkage studies indicate ...

Schizophrenia is a heterogeneous and multi-factored disease. Investigation of the disorder could profit from statistical methods which can address multiple putative factors and large, complex datasets. Machine learning is ...

Individuals with severe mental illness have much higher mortality rates from somatic diseases than the general population. Cardiovascular disease is the leading cause of death, and, contrary to the general population, ...

Background Beck Cognitive Insight Scale (BCIS) has been designed for assessment of self-reflection on patients' anomalous experiences and interpretations of own beliefs. The scale has been developed and ...

Background Consistent with global trends, the prevalence of obesity is increasing among Norwegian adults. This study aimed to investigate individual trends in BMI (kg/m2) by age, gender, and socio-economic ...

Background Mortality rates for older persons in Botswana have been unavailable and little is known of predictors of mortality in old age. This study may serve as a precursor for more detailed assessments. ...

BACKGROUND Opioid dependence is associated with substantial medical, psychological and social problems. Long-term opioid replacement therapy is the most common treatment option internationally. Ac-cording to Norwegian ...

Background The growing tendency among opioid addicts to misuse multiple other drugs should lead clinicians and researchers to search for new pharmacological strategies in order to prevent life-threatening ...

Background Relationships between cognitive deficits and brain morphological changes observed in schizophrenia are alternately explained by less gray matter in the brain cerebral cortex, by alterations in neural circuitry ...

Background The International Personality Disorders Examination (IPDE) constitutes the proposal of the WHO for the reliable diagnosis of personality disorders (PD). The IPDE assesses pathological personality ...