The aim of this literature review was to study the genetic predisposition to common obesity. Obesity is a major global health concern and is reaching epidemic proportions in both developed and developing countries significantly ...

Summary: Schizophrenia is a mental disorder which affects about 24 million people worldwide. It is caused by a complex interplay of genetic and environmental factors. It would be of value to find out which genes predispose ...

Cardiovascular diseases are a heterogeneous group of diseases whish still remains a major health problem in the healthcare system. This review merely focuses on the issue of ischemic heart disease and it’s complications, ...

We present the results of a global study of dysregulated miRNAs in paired samples of normal mucosa and tumor from eight patients with colorectal cancer. Although there is existing data of miRNAs contributing to colorectal ...

Mental retardasjon har en prevalens på 1-3 % i industrialiserte land iflg. WHO. Årsakene til mental retardasjon er mange og kan variere fra prematuritet, asfyksi, miljø/teratogene faktorer til genetiske avvik. Til tross ...

Multifactorial obesity and disposing genes. Abstract. Since the 1950’s obesity has become more and more common in the western world. The highest incidence is in the United States where 64 % of the population suffers from ...

1.Abstract: Fragile sites show susceptibility to DNA damage, leading to alterations that contribute to cancer development. They are associated with accumulation of unstable AT- and CCG-repeats which lead to ...

Despite substantial efforts for the better half of a century, the detailed etiology of non-syndromic orofacial clefts remains largely unknown. The objective of this paper is to present an updated overview of the subject ...

Introduction: There has in the recent years been an increase in biotechnological patents. Using Myriad Genetics’ patents on the genes BRCA 1 and -2 as an example I will attempt to illuminate the effect of gene patents on ...

Background: The prevalence of type 2 diabetes mellitus has increased dramatically in the western societies over the last few decades. This is probably a result of increasing prevalence of obesity. Nevertheless, the ilness ...

To determine the genetic causes of phenotypes, it is necessary to characterize the actual genotypic variation within linkage distance of the causative genetic code. There is however little knowledge about the DNA-variation ...

Chemotherapeutics are commonly used in the treatment of breast cancer, adjuvant to surgery and in the treatment of metastatic disease. However the ability of cancer cells to become resistant to different drugs remains a ...

Williams syndrome (WS) is characterized by cardiac and vessel malformations as well as cognitive abnormalities. The syndrome is caused by a 1.5-1.6 Mb deletion in the long arm of chromosome 7. The genes in this region are ...

In this experiment, mutant genes of a given unknown mutant strain of Drosophila melanogaster were mapped to specific chromosomes. Drosophila melanogaster, commonly known as the fruit fly, was the appropriate choice for ...